Promethegan is a prescription antihistamine medication used to treat allergic reactions and to prevent or treat nausea and vomiting caused by illness or motion sickness. It may also be used to help you feel sleepy or relaxed before and after surgery. The generic version of this drug is promethazine. The average retail price of 1, 12 suppository box of Promethegan is about $222.95. Pay just $26.83 for this medication by using a SingleCare Promethegan coupon at participating pharmacies. SingleCare coupons are available online for most prescription drugs and can also be reused for refills.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/20/2025
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Promethegan is a prescription antihistamine medication used to treat allergic reactions and to prevent or treat nausea and vomiting caused by illness or motion sickness. It may also be used to help you feel sleepy or relaxed before and after surgery. The generic version of this drug is promethazine. The average retail price of 1, 12 suppository box of Promethegan is about $222.95. Pay just $26.83 for this medication by using a SingleCare Promethegan coupon at participating pharmacies. SingleCare coupons are available online for most prescription drugs and can also be reused for refills.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Promethegan Retail Price | Promethazine Hcl Retail Price | Promethazine Hcl SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $90.00 | $90.00 | $45.60 |
| Walmart | - | $135.48 | $60.48 |
| Walgreens | $95.04 | - | - |
| Kroger Pharmacy | $129.48 | $116.52 | $45.60 |
| Albertsons Pharmacy | - | $180.96 | $53.52 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Promethegan is a prescription antihistamine medication used to treat allergic reactions and to prevent or treat nausea and vomiting caused by illness or motion sickness. It may also be used to help you feel sleepy or relaxed before and after surgery. The generic version of this drug is promethazine. The average retail price of 1, 12 suppository box of Promethegan is about $222.95. Pay just $26.83 for this medication by using a SingleCare Promethegan coupon at participating pharmacies. SingleCare coupons are available online for most prescription drugs and can also be reused for refills.
Without the necessary insurance coverage, you may end up paying as much as $222.95 for your Promethegan prescription. To save on this cost, use a SingleCare Promethegan coupon and pay only $26.83 for your Promethegan refill. These savings are redeemable at many local pharmacies.
Commercial healthcare plans typically offer Promethegan at varying prices, based on the type of plan you have and your level of coverage. You can pinpoint your exact Promethegan cost by visiting your local pharmacist and asking for assistance. You may be able to save even more on your Promethegan purchases by using SingleCare's Promethegan discount cards. Pay just $26.83 for Promethegan when you use SingleCare.
Promethegan is not always covered by Medicare Part D and Medicare Advantage plans. If you do qualify for coverage, your Medicare copay for Promethegan will depend on your plan's formulary and the coverage stage you're in. Save money on your prescription today by using a SingleCare Promethegan savings card and paying just $26.83 for your Promethegan prescription medication refill.
Promethegan is a brand-name prescription drug manufactured by G & W Laboratories, Inc. The generic version of this drug is promethazine.
Promethegan is an FDA-approved prescription antihistamine medication used to treat allergic reactions and to prevent or treat nausea and vomiting caused by illness or motion sickness. It may also be used to help you feel sleepy or relaxed before and after surgery. Promethegan works by blocking the effects of histamine that your body produces during an allergic reaction.
Promethegan comes in the form of a rectal suppository that is usually used two to four times daily. Remain laying down for a few minutes after using this medication and avoid having a bowel movement for an hour or longer to allow for the drug to be absorbed into your body.
If you are using this medication to treat motion sickness, take your first dose roughly 30 to 60 minutes before you begin traveling. For the treatment of allergies, use this medication once daily at bedtime. Your doctor will recommend an appropriate dose for you based on an assessment of your current medical condition, other drugs you are currently taking, and your response to treatment.
Promethegan may cause unwanted side effects such as dizziness, constipation, blurred vision, dry mouth, or drowsiness. Check with your doctor or pharmacist if you experience any of these effects and they persist or worsen. Many patients using this medication do not have any serious side effects.
In rare cases, this medication can cause a serious condition called neuroleptic malignant syndrome (NMS). Seek immediate medication attention if you experience any symptoms related to this condition such as fever, muscle stiffness, severe tiredness, confusion, sweating, dark urine, or irregular heartbeat.
Talk to your doctor or healthcare provider for full medical advice on the risks and benefits involved with using Promethegan as this is not a complete list of side effects.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved