Rasuvo Coupons & Prices

Rasuvo (methotrexate) is an FDA-approved prescription injectable drug prescribed to patients with rheumatoid arthritis or juvenile rheumatoid arthritis when other treatments have failed. It is also prescribed for patients with severe psoriasis, who have not responded to other treatments. Psoriasis is a disease that causes red, itchy, scaly patches on the skin. Continue to our FAQs section for more information about Rasuvo: how it works, possible side effects, how much Rasuvo costs, and how you can save on your Rasuvo prescription. Rasuvo cost is very high, normally $746.93 for 4, 0.5ml of 25mg/0.5ml pens at full retail price. A SingleCare Rasuvo coupon reduces the price to $570.22 for 4, 0.5ml of 25mg/0.5ml pens.

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Rasuvo coupon at Kroger Pharmacy
$573.22
$ 570.22
$3 off with signupwith signup

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Rasuvo coupon at Harris Teeter Pharmacy
$573.22
$ 570.22
$3 off with signupwith signup

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Rasuvo coupon at Walgreens Pharmacy
$579.97
$ 576.97
$3 off with signupwith signup
Rasuvo coupon at Publix Pharmacy
$ 614.56
Rasuvo coupon at Costco Pharmacy
$618.54
$ 615.54
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Rasuvo

Rasuvo (methotrexate) is an FDA-approved prescription injectable drug prescribed to patients with rheumatoid arthritis or juvenile rheumatoid arthritis when other treatments have failed. It is also prescribed for patients with severe psoriasis, who have not responded to other treatments. Psoriasis is a disease that causes red, itchy, scaly patches on the skin. Continue to our FAQs section for more information about Rasuvo: how it works, possible side effects, how much Rasuvo costs, and how you can save on your Rasuvo prescription. Rasuvo cost is very high, normally $746.93 for 4, 0.5ml of 25mg/0.5ml pens at full retail price. A SingleCare Rasuvo coupon reduces the price to $570.22 for 4, 0.5ml of 25mg/0.5ml pens.

About Rasuvo

Rasuvo (methotrexate) is an FDA-approved prescription injectable drug prescribed to patients with rheumatoid arthritis or juvenile rheumatoid arthritis when other treatments have failed. It is also prescribed for patients with severe psoriasis, who have not responded to other treatments. Psoriasis is a disease that causes red, itchy, scaly patches on the skin. Continue to our FAQs section for more information about Rasuvo: how it works, possible side effects, how much Rasuvo costs, and how you can save on your Rasuvo prescription. Rasuvo cost is very high, normally $746.93 for 4, 0.5ml of 25mg/0.5ml pens at full retail price. A SingleCare Rasuvo coupon reduces the price to $570.22 for 4, 0.5ml of 25mg/0.5ml pens.

Rasuvo FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Rasuvo cost without insurance?

At most pharmacies, the full cash price of Rasuvo will be $746.93 for 4, 0.5ml of 25mg/0.5ml pens. That same prescription will cost $570.22 for 4, 0.5ml of 25mg/0.5ml pens using a SingleCare prescription savings card, which you can use at participating pharmacies throughout the country. Some insurances may require Rasuvo to be filled at a specialty pharmacy. You can contact your specialty pharmacy to see if they accept SingleCare discount coupons. 

How much does Rasuvo cost with insurance?

Rasuvo costs differ depending on your insurance plan and could be very high. With SingleCare, Rasuvo costs only $570.22 for 4, 0.5ml of 25mg/0.5ml pens. Ask your pharmacist to compare your Rasuvo insurance copay to your SingleCare Rasuvo discount card to ensure you pay the lowest price

Does Medicare cover Rasuvo and how much does it cost?

Medicare Advantage and Medicare Part D prescription drug insurance plans do not provide coverage for Rasuvo. Medicare B sometimes covers Rasuvo. If you are on Medicare, look into using a SingleCare Rasuvo coupon for your prescription. With SingleCare, the price of Rasuvo is $570.22 for 4, 0.5ml of 25mg/0.5ml pens.

Is there a generic of Rasuvo?

The ingredient in the Rasuvo injection is called methotrexate. There is not currently a generic for Rasuvo, but methotrexate is available in tablet form. Oral methotrexate is primarily prescribed as chemotherapy for patients with certain types of cancer: leukemia and lymphoma. In this capacity, methotrexate works by killing cancer cells. Oral methotrexate is also sometimes prescribed for rheumatoid arthritis or severe psoriasis.

The good news is that generic methotrexate is covered by all Medicare prescription drug insurance programs and generally has a low copay when used with other health insurance plans. Consult with your physician about the pros and cons of using oral generic methotrexate in place of injectable Rasuvo.

What is Rasuvo?

Rasuvo (methotrexate) is a prescription drug prescribed to patients with rheumatoid arthritis or juvenile rheumatoid arthritis when other treatments have failed. It is also prescribed for patients with severe psoriasis, a disease that causes the skin to develop dry, hard, itchy patches in some places. 

Rasuvo comes in the form of an auto-injector, which the patient uses to inject Rasuvo into the abdomen or thigh once per week. Patients generally report symptom relief in three to twelve weeks.

Rasuvo should not be taken as a cancer treatment. Rasuvo should not be used in women who are pregnant or breastfeeding.

Rasuvo is not right for everyone. Before taking Rasuvo, tell your doctor about all of your medical conditions and all of the medicines you take. This will help your doctor decide if Rasuvo is safe for you. 

What are the side effects of Rasuvo?

Common side effects of Rasuvo include, but are not limited to, nausea, stomach pain, indigestion, mouth sores, and rash.

Methotrexate, the active ingredient in Rasuvo, kills cells in the body. In larger doses than Rasuvo, it can damage organs and reduce blood cell counts. Your blood should be tested regularly when you are taking Rasuvo. Patients using Rasuvo are also at a higher risk of certain cancers, such as non-Hodgkin's lymphoma.

Severe side effects of Rasuvo depend on the dosage, but you should consult your doctor if you have diarrhea, black and tarry stools, or bloody vomiting. Tell your doctor if you have cough, shortness of breath, stomach pain, dark urine, numbness, tingling, muscle weakness, confusion, seizures, or a skin rash with blistering and peeling. Allergic reactions are rare, but if you have symptoms of hives, difficulty breathing, or swelling around the face, lips, tongue, or throat, get emergency medical help right away. 

Rasuvo may also reduce fertility, and can cause lower sperm counts in men and disruption of the menstrual cycle in women.

Rasuvo also suppresses the body's immune system, so patients are more susceptible to infections and certain cancers. 

Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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Where are Rasuvo coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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