What is Remodulin? Uses, warnings & side effects

Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

You will need to continue using this medicine for a long period of time, possibly for many years. Talk with your doctor if you have any concerns about this.

Ask your doctor who to call if you have any problems with the infusion pump. You may be given a second infusion pump to have in case the first pump stops working. Make sure you have access to this pump as a backup at all times.

Injection routeUse a new needle and syringe each time you inject your medicine.

Injection routeYou will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.

Your doctor or nurse will teach you how to prepare the medicine and how to use the pump for the infusion. Treprostinil must be given continuously by a portable pump. The instructions for the pump may vary depending on the particular make and model. You will be given detailed instructions on how to use and care for your pump and accessories. Make sure you understand all of the instructions before giving yourself an infusion.

Check the liquid in the vial. If the liquid has changed color, is cloudy, or has particles in it, do not use it.

Your doctor will prescribe your exact dose and tell you how often it should be given. A nurse or other trained health professional will teach you or a caregiver how to give this medicine. The medicine is given as an infusion through a catheter that is placed directly under your skin or into a vein. Do not use more medicine than your doctor tells you to.

Missed dose: Injection routeCall your doctor or pharmacist for instructions.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. You may keep the medicine for up to 30 days at room temperature after you open the vial and use your first dose. You will use a syringe to take medicine from the vial and insert the syringe into the pump.

Injection routeYou will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.

Injection routeUse a new needle and syringe each time you inject your medicine.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. You may keep the medicine for up to 30 days at room temperature after you open the vial and use your first dose. You will use a syringe to take medicine from the vial and insert the syringe into the pump.

Ask your doctor who to call if you have any problems with the infusion pump. You may be given a second infusion pump to have in case the first pump stops working. Make sure you have access to this pump as a backup at all times.

Your doctor or nurse will teach you how to prepare the medicine and how to use the pump for the infusion. Treprostinil must be given continuously by a portable pump. The instructions for the pump may vary depending on the particular make and model. You will be given detailed instructions on how to use and care for your pump and accessories. Make sure you understand all of the instructions before giving yourself an infusion.

Your doctor will prescribe your exact dose and tell you how often it should be given. A nurse or other trained health professional will teach you or a caregiver how to give this medicine. The medicine is given as an infusion through a catheter that is placed directly under your skin or into a vein. Do not use more medicine than your doctor tells you to.

Check the liquid in the vial. If the liquid has changed color, is cloudy, or has particles in it, do not use it.

You will need to continue using this medicine for a long period of time, possibly for many years. Talk with your doctor if you have any concerns about this.

Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Missed dose: Injection routeCall your doctor or pharmacist for instructions.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Injection routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. Throw away old medicine after the expiration date has passed.

Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

If your must stop your infusion, call your doctor or pharmacist for instructions first.

Look at the liquid in the vial. If the liquid has particles or specks in it or if the liquid has changed color, do not use the vial.

After you open the vial and use your first dose, the medicine will keep for up to 30 days at room temperature. You will use a syringe to take medicine from the vial and insert the syringe into the pump. The medicine in the syringe can be used for up to 72 hours.

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to treprostinil.

Swelling in your hands, ankles, or feet.

Severe redness, pain, rash, swelling, or a hard lump where the needle is placed.

Do not suddenly stop receiving this medicine. Stopping the medicine suddenly may worsen the symptoms of your condition. Check with your doctor before stopping it completely.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

This medicine can cause the following problems:Increased risk of infection (including blood stream infection, sepsis) when given through a catheterLow blood pressureIncreased risk of bleeding

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, low blood pressure, or bleeding problems.

Make sure your doctor knows if you are also using medicine to lower blood pressure. Some blood pressure medicines are atenolol, lisinopril, metoprolol, quinapril, Accupril®, Cozaar®, Diovan®, Lotrel®, Norvasc®, Toprol®, or Zestril®.

Tell your doctor if you use a diuretic ("water pill") such as furosemide, hydrochlorothiazide (HCTZ), indapamide, metolazone, spironolactone, torsemide, triamterene, Aldactone®, Demadex®, Lasix®, Lozol®, Maxzide®, or Zaroxolyn®.

Some medicines can affect how treprostinil works. Tell your doctor if you are using any of the following:Aspirin, gemfibrozil, rifampinBlood pressure medicineBlood thinner (including warfarin)Diuretic (water pill)NSAID pain or arthritis medicine (including diclofenac, ibuprofen, naproxen)