Restasis is a prescription eye drop known by the generic name cyclosporine. It works as an immunosuppressant agent that helps reduce inflammation in the eye and increase tear production. It comes in single-use vials or multi-dose bottles and is approved for chronic dry eye symptoms in adults and children 16 and older. Although Restasis is an effective long-term medication, it may still come with side effects, and it should only be used as prescribed by a healthcare provider.
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Restasis overview
BRAND NAMES:
Restasis
Generic Names:
Cyclosporine ophthalmic emulsion
Uses:
Treats symptoms of chronic dry eye
Therapeutic Classes:
Calcineurin inhibitor, immunosuppressant, ophthalmic agent
Forms:
Eye drop, ophthalmic emulsion
How it’s taken:
Into the eye
What is Restasis used for?
Restasis is an eyedrop medication used to manage chronic dry eye, a condition caused by inflammation and insufficient tear production. Restasis is not a cure for dry eye but rather a treatment for symptoms. It is typically used for long-term relief, and patients may need to use it for up to three months before they see the full benefits. It is not approved for eye conditions that aren’t related to dry eye caused by inflammation.
Expert tips for using Restasis
Restasis, also known by its generic name cyclosporine, is an eyedrop medication used to increase tear production in those with chronic dry eye. Restasis is not an instant fix; it may take a few months for an increase in tear production and full symptom relief to be noticeable.
Patients typically administer one drop of Restasis in each eye twice per day, spaced about 12 hours apart. Use Restasis consistently, as directed by a healthcare provider. Not taking Restasis may lead to reduced effectiveness or increased side effects.
Like any medication, Restasis may lead to side effects. Some people might experience eye burning, redness, or discharge. Those who are concerned about these or other side effects should also consult their healthcare provider for medical advice.
Before starting Restasis, individuals should discuss their medical history with a healthcare provider, especially if it involves allergies to cyclosporine, eye infections, or the use of contact lenses. Restasis may not be suitable for everyone. A healthcare provider can determine whether Restasis is the most appropriate treatment option.
What form(s) does Restasis come in
Eye drop emulsion
0.05%
What are common Restasis doses?
Instill one drop into each eye twice daily, approximately 12 hours apart.
Common Restasis prescriptions
Restasis
30 of 0.05% boxRestasis
60 of 0.05% box
How to take Restasis
Your doctor will tell you how much medicine to use. Do not use more than directed.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Turn the package upside down a few times to mix the medicine before you use it. Use the medicine right away after you open the package.
Wash your hands with soap and water before and after using this medicine.
To use the eye drops:
Lie down or tilt your head back.
With your index finger, pull down the lower lid of your eye to form a pocket.
Hold the dropper close to your eye with the other hand.
Drop the correct number of drops into the pocket made between your lower lid and eyeball.
Gently close your eyes.
Place your index finger over the inner corner of your eye for one minute.
Do not rinse or wipe the dropper or allow it to touch anything, including your eye.
You might not use all of the medicine in each single-use vial. Discard each single-use vial after using it, even if there is solution remaining.
Wait at least 15 minutes before you use other lubricant eye drops (including artificial tears).
If you wear contact lenses, take them out before you use this medicine. Wait at least 15 minutes before you put your contact lenses back in.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
What to do if you miss a dose of Restasis
Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
Consult your healthcare provider if you have concerns about a missed dose or you're frequently missing doses. Your healthcare provider can provide strategies to remember your dosages or may consider an adjustment to your treatment plan if necessary.
Restasis contraindications
This medicine is not right for everyone. Do not use it if you have had an allergic reaction to cyclosporine.
Restasis warnings
If you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your healthcare provider right away. You may need to change your medicine or stop using it.
Call your healthcare provider if your symptoms do not improve or if they get worse.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Tell your healthcare provider if you are pregnant or breastfeeding. Studies are limited on the effects of Restasis on an unborn baby or breastfeeding child.
The eye drops may cause burning or stinging sensations when initially applied. If these symptoms persist or worsen, contact your healthcare provider
Do not touch the tip of the vial or dropper to any surface, including the eyes, to prevent contamination.
Restasis interactions
Restasis is not significantly absorbed into the body and is not known to interact with other medications. However, if you are using other products or medications for the eyes, wait at least 15 minutes between using the other product and Restasis.
Restasis side effects
Restasis may cause side effects that can vary among individuals. While some people do not experience any adverse effects, others may experience mild to serious reactions.
Serious Side Effects
Allergic reactions, with symptoms like severe itching or hives, severe swelling in the face or eyelids, chest tightness, or trouble breathing
Severe eye pain due to eye injury
Eye infections caused by contamination of the eyedropper
Less Serious Side Effects
Eye redness or discomfort
Feeling like something is in the eye
Mild, brief burning in the eyes
Red, watery, or itchy eyes
Temporary blurred vision
RELATED: Xiidra vs. Restasis
Sources:
Restasis highlights of prescribing information, U.S. Food and Drug Administration (2017)
Patient and physician perspectives on the use of cyclosporine ophthalmic emulsion 0.05% for the management of chronic dry eye, Clinical Ophthalmology (2018)
Restasis drug label information, DailyMed (2017)
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