Salsalate is a generic prescription drug similar to aspirin that is used to relieve pain and swelling due to osteoarthritis, rheumatoid arthritis, and other rheumatic disorders (rheumatism of the tendons, muscles, ligaments, bones, and spine). Salsalate belongs to a class of medications called non-steroidal anti-inflammatory drugs that work by blocking substances in the body that cause inflammation (swelling) and its attendant pain and stiffness. On average, Salsalate costs $111.64 but you will pay only $39.54 per 60, 500mg tablets with a free SingleCare Salsalate coupon.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/04/2026
Salsalate is a generic prescription drug similar to aspirin that is used to relieve pain and swelling due to osteoarthritis, rheumatoid arthritis, and other rheumatic disorders (rheumatism of the tendons, muscles, ligaments, bones, and spine). Salsalate belongs to a class of medications called non-steroidal anti-inflammatory drugs that work by blocking substances in the body that cause inflammation (swelling) and its attendant pain and stiffness. On average, Salsalate costs $111.64 but you will pay only $39.54 per 60, 500mg tablets with a free SingleCare Salsalate coupon.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Salsalate Retail Price | Salsalate SingleCare Price |
|---|---|---|
| CVS Pharmacy | $97.80 | $46.20 |
| Walgreens | $97.20 | $96.60 |
| Kroger Pharmacy | $102.60 | $93.60 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Salsalate is a generic prescription drug similar to aspirin that is used to relieve pain and swelling due to osteoarthritis, rheumatoid arthritis, and other rheumatic disorders (rheumatism of the tendons, muscles, ligaments, bones, and spine). Salsalate belongs to a class of medications called non-steroidal anti-inflammatory drugs that work by blocking substances in the body that cause inflammation (swelling) and its attendant pain and stiffness. On average, Salsalate costs $111.64 but you will pay only $39.54 per 60, 500mg tablets with a free SingleCare Salsalate coupon.
Patients can usually expect to pay $111.64 for 60, 500mg tablets of Salsalate. Compare this price to the cost of Salsalate with a SingleCare coupon: $39.54 for 60, 500mg tablets. For all your prescription needs, a SingleCare savings card can save you as much as 80% on your purchases.
Check with your pharmacist about your copay for a Salsalate prescription, since it can vary based on your insurance plan. Also, ask your pharmacist to compare your copay to your cost using a SingleCare Salsalate coupon. At $39.54 for your Salsalate prescription of 60, 500mg tablets, your SingleCare price may be lower.
Salsalate is usually not covered by Medicare Part D and Medicare Advantage prescription drug plans. People with Medicare can use a SingleCare Salsalate coupon instead and lower their cost to as little as $39.54 for 60, 500mg tablets.
Salsalate is a generic prescription pain relief medication. Salsalate is also the active ingredient in the brand-name prescription drug, Disalcid (tablet), from Avion. A SingleCare discount card will save you on all versions of Salsalate at local pharmacies near you, such as Target or Walgreens.
Salsalate is a generic prescription drug similar to aspirin that is used to relieve pain and swelling due to osteoarthritis, rheumatoid arthritis, and other rheumatic disorders, such as rheumatism of the tendons, muscles, ligaments, bones, and spine.
Salsalate belongs to a class of medications called non-steroidal anti-inflammatory drugs that work by blocking substances in the body that cause inflammation (swelling), pain, and fever. Salsalate is as effective as aspirin at reducing swelling, but does not thin the blood as much as aspirin does. Substituting Salsalate for aspirin means lowering the risk for bleeding, bruising, and gastrointestinal problems that are often caused by aspirin.
Salsalate is taken as a tablet two or three times a day in immediate-release format. Salsalate is not available in an extended-release format.
Side effects of Salsalate include upset stomach, heartburn, dizziness, hearing problems, ringing in the ears, fast heartbeat, and dark urine.
Allergic reactions are rare and include itching, hives, swelling, and skin rash. Salsalate should be discontinued immediately if allergic reactions are experienced.
This is not a complete list of side effects that may occur. If you have concerns or questions about side effects, consult with your prescribing physician.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved