What is Savella Titration Pack: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Savella Titration Pack overview

BRAND NAMES:

  • Savella, Savella Titration Pack

Generic Names:

  • Savella Titration Pack

Uses:

  • Treats fibromyalgia. This medicine is an SSNRI.

Therapeutic Classes:

  • Central Nervous System Agent

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Savella Titration Pack used for?

What form(s) does Savella Titration Pack come in

  • Tablet

What are common Savella Titration Pack doses?

  • Disp Pack 55 Miscellaneous

Common Savella Titration Pack prescriptions

  • Savella Titration Pack
    55 miscellaneous disp pack

How to take Savella Titration Pack

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: If you miss a dose, skip the missed dose and take your next dose at your regularly scheduled time.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: If you miss a dose, skip the missed dose and take your next dose at your regularly scheduled time.

What to do if you miss a dose of Savella Titration Pack

Savella Titration Pack contraindications

  • This medicine is generally considered safe for most people. Talk to your doctor if you have concerns.

Savella Titration Pack warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, heart rhythm problems, high blood pressure, glaucoma, an enlarged prostate, or a history of painful or difficult urination. Also tell your doctor if you have a history of seizures, or if you drink alcohol.

  • This medicine may cause the following problems:Serotonin syndrome (more likely when used with certain other medicines)High blood pressureLiver problemsHyponatremia (low sodium levels)Higher risk of bleeding problems (especially if used with a blood thinner or NSAID medicine)

  • For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.

  • This medicine may make you drowsy or less alert. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Your blood pressure and heart rate will also be monitored while you use this medicine.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Increased energy, racing thoughts, reckless behavior, talking more than usual

  • Seizures or tremors

  • Unusual behavior or thoughts about hurting yourself or others

  • Unusual bleeding or bruising

Savella Titration Pack interactions

  • Do not use this medicine if you have used an MAO inhibitor (MAOI) within the past 14 days. Do not take an MAOI for at least 5 days after stopping this medicine.

  • Some medicines can affect how milnacipran works. Tell your doctor if you are using any of the following:Buspirone, clomipramine, clonidine, digoxin, fentanyl, lithium, St John's wort, tramadol, or tryptophan supplementAmphetaminesBlood thinner (including warfarin)Diuretic (water pill)NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)Tricyclic antidepressant or other medicine to treat depressionTriptan medicine to treat migraine headaches.

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • This medicine may make you drowsy or less alert. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Your blood pressure and heart rate will also be monitored while you use this medicine.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Savella Titration Pack side effects

Serious Side Effects

  • Unusual behavior or thoughts about hurting yourself or others

  • Fast, pounding, or uneven heartbeat or pulse

  • Unusual bleeding or bruising

  • Increased energy, racing thoughts, reckless behavior, talking more than usual, trouble sleeping

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Anxiety, restlessness, fever, sweating, muscle spasms, diarrhea, seeing or hearing things that are not there

  • Blistering, peeling, red skin rash

  • Confusion, weakness, and muscle twitching

  • Seizures or tremors

  • Eye pain, vision changes, seeing halos around lights

Less Serious Side Effects

  • Constipation

  • Warmth or redness in your face, neck, arms, or upper chest

  • Mild headache or dizziness

  • Mild headache, dizziness, trouble sleeping

  • Problems with urination or sex

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