Prescription toothpastes have high levels of sodium fluoride. The highest concentration products are marketed as sodium fluoride 5000 or sodium fluoride 1.1% toothpastes or gels. That’s five times the concentration of sodium fluoride in store-bought toothpastes. The extra sodium fluoride provides much more cavity-fighting protection and can remineralize decayed teeth. However, there is a significant risk of fluoride poisoning, especially in children.
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Allday 5000, Clinpro 5000, Denta 5000 Plus, Fluoridex, PreviDent 5000, SF 1.1%, SF 5000
Sodium fluoride 5000, sodium fluoride 1.1%
Prevents cavities and tooth decay
Cariostatic, dentifrice
Cream, gel
Brushed on the teeth
Prescription sodium fluoride 5000 toothpastes and gels prevent cavities and reverse tooth decay. It is prescribed to adults and children 6 years of age and older who are significantly at risk for cavities or who have high levels of tooth decay.
Cream (toothpaste)
1.1% (5000 ppm)
Gel
1.1% (5000 ppm)
For the prevention of cavities or to treat tooth decay: Brush the teeth thoroughly with a thin strip of paste or gel for two minutes once daily, preferably at bedtime, or twice daily (sensitive formulations).
Sodium Fluroide 5000
100ml of 1.1% tube
Sodium Fluroide 5000
100ml of 1.1-5% tube
Sodium Fluroide 5000
51gm of 1.1% tube
Sodium Fluroide 5000
51gm of 1.1% tube of cream
Sodium Fluroide 5000
100ml of 1.1% tube of gel
Sodium Fluroide 5000
100ml of 1.1% tube of paste
The prescriber will tell you how much medicine to use, how often to use the product, and when to use the product. Do not use more than directed.
Do not swallow this medicine. It is for topical use on your teeth only.
Use sodium fluoride 5000 products once daily in place of regular toothpaste, preferably at bedtime.
Use sodium fluoride 5000 products with potassium nitrate (sensitive formulations) twice daily in place of regular toothpaste, once in the morning and once in the evening.
Apply a thin strip of paste or gel to a toothbrush.
Brush your teeth thoroughly for one or two minutes (instructions will vary by product).
Spit out after brushing.
Do not rinse your mouth, eat, or drink for 30 minutes.
Children should rinse their mouths immediately after use and spit out the rinse.
Store sodium fluoride 5000 paste or gel at room temperature.
Ask the prescriber what to do in case a dose is missed.
Do not take extra medicine to make up for a missed dose.
Do not use on a child younger than 6 unless the prescriber instructs you to.
If sodium fluoride 5000 is prescribed to a child younger than 6, an adult should supervise the child to prevent swallowing during brushing.
Before starting sodium fluoride 5000, tell the prescriber if you are pregnant, breastfeeding, or have allergies.
Adults should always supervise children using this product to ensure they do not swallow the medicine.
Regularly using too much sodium fluoride 5000, can cause white patches or stains on the teeth. If this happens, stop using the medicine and call the prescriber.
Do not swallow this toothpaste, or let a child swallow it or get into it accidentally.
Ingesting large amounts of this toothpaste can cause serious side effects.
If a small amount of the paste or gel is eaten, drink milk or eat another food rich in soluble calcium.
If large amounts are eaten, induce vomiting, supply soluble calcium (like milk), and get emergency medical care.
Always keep this product out of the reach of children.
Sodium fluoride 5000 products have no serious drug interactions.
Serious side effects
Contact a healthcare provider or get medical attention if you notice any signs or symptoms of a possible serious side effect:
Tooth discoloration
Overdose: Nausea, vomiting, vomiting blood, stomach cramps, stomach pain, diarrhea, excess salivation
Allergic reactions: itching, hives, skin rash, swelling of the mouth, lips, or tongue
Advice on high fluoride toothpastes, The Pharmaceutical Journal
Denta 5000 Plus sodium fluoride gel prescribing information, DailyMed (NIH National Library of Medicine)
Prevident 5000 Sensitive sodium fluoride and potassium nitrate gel prescribing information, DailyMed (NIH National Library of Medicine)
SF 1.1% sodium fluoride gel prescribing information, DailyMed (NIH National Library of Medicine)
SF 5000 Plus 1.1% sodium fluoride prescription dental cream prescribing information, DailyMed (NIH National Library of Medicine)
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved