Sulfamylon Coupons & Prices

Sulfamylon is a prescription topical antibiotic that prevents infection of second- and third-degree burns as well as skin grafts. Sulfamylon is applied as a cream or solution. The active ingredient in Sulfamylon is mafenide acetate, a sulfa drug that prevents bacteria from reproducing. Sulfamylon is usually administered by a healthcare professional but may also be purchased at pharmacies. Currently, Sulfamylon costs $95.32. A SingleCare Sulfamylon coupon reduces the price of Sulfamylon to $72.84 at participating pharmacies, such as CVS, Target, and Longs Drugs, among others.

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0.125 jar453.6gm of 85mg/gmEdit

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Sulfamylon coupon at Kroger Pharmacy
$75.84
$ 72.84
$3 off with signupwith signup

Show this free card to your pharmacist.

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Sulfamylon coupon at Harris Teeter Pharmacy
$75.84
$ 72.84
$3 off with signupwith signup

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Sulfamylon coupon at Costco Pharmacy
$81.49
$ 78.49
$3 off with signupwith signup
Sulfamylon coupon at Walmart Neighborhood Market Pharmacy
$81.56
$ 78.56
$3 off with signupwith signup
Sulfamylon coupon at Walmart Pharmacy
$81.56
$ 78.56
$3 off with signupwith signup
Sulfamylon coupon at Publix Pharmacy
$83.62
$ 80.62
$3 off with signupwith signup
$ 81.88
$87.34
$ 84.34
$3 off with signupwith signup
$97.39
$ 94.39
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Sulfamylon

Sulfamylon is a prescription topical antibiotic that prevents infection of second- and third-degree burns as well as skin grafts. Sulfamylon is applied as a cream or solution. The active ingredient in Sulfamylon is mafenide acetate, a sulfa drug that prevents bacteria from reproducing. Sulfamylon is usually administered by a healthcare professional but may also be purchased at pharmacies. Currently, Sulfamylon costs $95.32. A SingleCare Sulfamylon coupon reduces the price of Sulfamylon to $72.84 at participating pharmacies, such as CVS, Target, and Longs Drugs, among others.

Sulfamylon Price History & Information

Price History for Sulfamylon

1 count, jar, 453.6gm of 85mg/gm

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Sulfamylon

1 count, jar, 453.6gm of 85mg/gm
PharmacySulfamylon Retail PriceSulfamylon SingleCare Price
Walgreens$86.75$79.38
Kroger Pharmacy$86.75$75.98

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Sulfamylon

Sulfamylon is a prescription topical antibiotic that prevents infection of second- and third-degree burns as well as skin grafts. Sulfamylon is applied as a cream or solution. The active ingredient in Sulfamylon is mafenide acetate, a sulfa drug that prevents bacteria from reproducing. Sulfamylon is usually administered by a healthcare professional but may also be purchased at pharmacies. Currently, Sulfamylon costs $95.32. A SingleCare Sulfamylon coupon reduces the price of Sulfamylon to $72.84 at participating pharmacies, such as CVS, Target, and Longs Drugs, among others.

Sulfamylon FAQs

How much does Sulfamylon cost without insurance?

The price for Sulfamylon without insurance averages around $95.32 per 1, 56.7gm of 85mg/gm tube of cream, but this price may vary. Sulfamylon is often applied by a healthcare professional and billed by the clinic or hospital where it is applied, so the price can vary dramatically from the pharmacy price. With a SingleCare Sulfamylon discount card, a prescription for 1, 56.7gm of 85mg/gm tube of cream of Sulfamylon costs $72.84.

How much does Sulfamylon cost with insurance?

The copay cost for Sulfamylon will vary. It is often applied in an emergency or clinical setting by a healthcare professional, so the cost may be covered by health insurance. Purchased at a pharmacy, the copay cost will vary depending on the insurance plan. You can ask your pharmacist to compare your copay cost to your price using a SingleCare discount card. You might save more by using SingleCare.

Does Medicare cover Sulfamylon and how much does it cost?

Medicare prescription drug plans do not cover Sulfamylon prescriptions.

For Medicare patients with a prescription for Sulfamylon, you’ll pay as little as $72.84 for 1, 56.7gm of 85mg/gm tube of cream of Sulfamylon with a SingleCare Sulfamylon at participating pharmacies.

Is there a generic of Sulfamylon?

Sulfamylon is a brand-name topical antibiotic (mafenide acetate) for serious burns and skin grafts. It is available as a powder (for reconstitution in sterile water) and a cream. Generic mafenide acetate is available as a powder for reconstitution and is covered by most Medicare prescription drug plans. There are no generic mafenide acetate creams. Search the SingleCare website to find coupons for mafenide acetate as well as more information.

What is Sulfamylon?

Sulfamylon is an over-the-counter topical antibiotic that prevents bacterial infection serious burns (second- and third-degree) and skin grafts. The active ingredient in Sulfamylon, mafenide acetate, belongs to a class of antibiotics called sulfa drugs. These drugs interfere with the bacteria's ability to use folate to make copies of its DNA and produce new bacteria cells.

Sulfamylon is available as a cream or powder for reconstitution. The cream can be found at pharmacies and is used for the home care of serious burns. The powder is more frequently used by healthcare professionals in an emergency or clinical setting. It is reconstituted in sterile water and used to keep wound dressings wet either using irrigation tubing or a syringe.

What are the side effects of Sulfamylon?

Some but not all common side effects of Sulfamylon are primarily site reactions and include skin redness, itching, rash, blistering, burning, or pain. Acidosis (too much acid in the blood) frequently results from the prolonged use of mafenide acetate on burns. Healthcare providers will discontinue the use of Sulfamylon for one or two days to help restore normal acid-base levels in the blood. Allergic reactions to sulfa drugs are common. Again, healthcare providers will discontinue Sulfamylon when they notice signs of an allergic reaction such as hives, facial swelling, or trouble breathing.

These are not all the possible side effects of Sulfamylon. Always consult with your physician or pharmacist if you have any worries or questions about possible side effects.

Where are Sulfamylon coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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