What is Trifluridine: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Trifluridine overview

BRAND NAMES:

  • Viroptic, Viroptic

Generic Names:

  • Trifluridine

Uses:

  • Treats virus infections of the eye.

Therapeutic Classes:

  • Antiviral

Forms:

  • Drop

How it’s taken:

  • Into the eye

What is Trifluridine used for?

What form(s) does Trifluridine come in

  • Drop

What are common Trifluridine doses?

  • Bottle 7.5ML of 1%

Common Trifluridine prescriptions

  • Trifluridine
    7.5ml of 1% bottle

How to take Trifluridine

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • This medicine is not for long-term use.

  • Ophthalmic routeWash your hands with soap and water before and after using this medicine.

  • Ophthalmic routeLie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • Ophthalmic routeShake the eye drops well just before each use.

  • Ophthalmic routeTo use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • This medicine is not for long-term use.

  • Ophthalmic routeLie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • Ophthalmic routeShake the eye drops well just before each use.

  • Ophthalmic routeWash your hands with soap and water before and after using this medicine.

  • Ophthalmic routeTo use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.

What to do if you miss a dose of Trifluridine

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Ophthalmic routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine container and any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Trifluridine contraindications

  • You should not use this medicine if you have had an allergic reaction to trifluridine.

Trifluridine warnings

  • If your symptoms are not any better after 1 week, tell your doctor.

  • Make sure your doctor knows if you are pregnant or breastfeeding.

  • Increased eye irritation (redness, swelling, or pain) than before you started using the drops.

Trifluridine interactions

  • If your symptoms are not any better after 1 week, tell your doctor.

  • Talk with your doctor or pharmacist before using any other products for the eye.

Trifluridine side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Increased eye irritation (redness, swelling, or pain) than before you started using the drops.

  • Blurred vision or other change in vision.

Less Serious Side Effects

  • Mild burning, dryness, or stinging of the eye.

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