Winlevi is a prescription topical acne treatment. Its active ingredient, clascoterone, works by blocking testosterone from increasing oil production in the skin’s oil glands. Excess skin oil production is the first step in the development of pimples. Patients apply Winlevi cream to the affected skin twice daily. The most common side effects are skin reactions like redness or irritation.
Winlevi
Clascoterone
Treats acne.
Antiacne, antiandrogen
Cream
Applied to the skin
Winlevi is an acne treatment for adults and children 12 years of age and older.
Cream
1%
For acne vulgaris in adults and children 12 years of age and older: Apply a thin layer of cream to the affected skin twice daily
Winlevi
60gm of 1% tube
Winlevi
60gm of 1% tube of cream
Your doctor will tell you how much medicine to use. Do not use more than directed.
Please read the Patient Information sheet that comes with the medicine.
Use Winlevi only on the skin.
Do not get Winlevi cream into your eyes, nose, mouth, corners of the nose, or vagina. If you do, rinse the area with water.
Do not use Winlevi on skin with cuts, scrapes, sunburn, or rash.
Use twice daily. Apply one dose in the morning and one dose in the evening.
Applying a dose:
Gently wash and dry the affected skin area.
Apply a thin, even layer of the cream to the affected skin.
Wash your hands when finished.
Store Winlevi cream at room temperature. Do not freeze.
Dispose of any remaining medicine 180 days after picking it up at the pharmacy or one month after opening it, whichever is soonest.
Ask the prescriber how to manage a missed dose.
Do not apply extra medicine to make up for a missed dose.
Winlevi does not have contraindications.
Tell other doctors and healthcare providers you are using this medication when they treat you.
Tell the prescriber if you are pregnant, breastfeeding, or have:
Eczema
Sunburn
Other skin problems
This medicine may suppress your body’s ability to produce cortisol or it may cause potassium levels to increase. In clinical trials, these problems were not advanced enough to produce symptoms. The dermatologist or other healthcare provider treating you may need regular blood tests and office visits to monitor for these problems. Keep all appointments.
Do not use any other medicines on the treated skin areas without consulting with the prescriber.
Tell other doctors who treat you about Winlevi before they prescribe new topical medications.
When taking Winlevi, avoid skincare products that irritate or dry the skin such as:
Medicated soaps or cleansers
Abrasive soaps or cleansers
Skin cleansers or other products that dry the skin
Alcohol-containing products
Astringents
Spices
Lime
Serious side effects
Winlevi can cause some serious but subclinical side effects, that is, side effects with no symptoms or other problems. These include elevated potassium and suppression of the body’s ability to produce the hormone cortisol (HPA suppression). Because these are subclinical side effects, patients using Winlevi should keep all appointments with the prescriber and take all requested blood tests.
Just in case, tell the prescriber if you notice a cluster of symptoms that could be caused by HPA suppression such as:
Tiredness or fatigue that is not relieved by sleeping
Weight gain, muscle aches, joint pain, food cravings, light sensitivity, facial swelling
Infections, inflammation, slow wound healing
Dizziness, brain fog, sleeplessness, difficulty waking up
Irritability, depression, anxiety, decreased interest in sex
There are no reports of severe allergic reactions to Winlevi.
Less serious side effects
Application site reactions such as itching, burning, redness, or peeling
Clascoterone (Winlevi) for the treatment of acne, American Family Physician
Winlevi, Sun Dermatology
Winlevi clascoterone cream prescribing information, DailyMed (NIH National Library of Medicine)
Winlevi HCP, Sun Dermatology
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© 2025 SingleCare Administrators. All rights reserved