Zurzuvae is used to treat postpartum depression in adults. It is generally prescribed to be taken once a day in the evening for 14 days and should be taken with food that contains fat. The average retail price of Zurzuvae is $19,118.75 per 28, 25mg capsules, but patients can pay just $17,125.17 for 28, 25mg capsules of Zurzuvae with a card or coupon from SingleCare’s discount program. Zurzuvae is a brand-name drug and was approved by the U.S. Food and Drug Administration (FDA) in 2023.
Edit your dosage
14 capsule, 20mgEdit
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 03/23/2026
Zurzuvae is used to treat postpartum depression in adults. It is generally prescribed to be taken once a day in the evening for 14 days and should be taken with food that contains fat. The average retail price of Zurzuvae is $19,118.75 per 28, 25mg capsules, but patients can pay just $17,125.17 for 28, 25mg capsules of Zurzuvae with a card or coupon from SingleCare’s discount program. Zurzuvae is a brand-name drug and was approved by the U.S. Food and Drug Administration (FDA) in 2023.
Zurzuvae is used to treat postpartum depression in adults. It is generally prescribed to be taken once a day in the evening for 14 days and should be taken with food that contains fat. The average retail price of Zurzuvae is $19,118.75 per 28, 25mg capsules, but patients can pay just $17,125.17 for 28, 25mg capsules of Zurzuvae with a card or coupon from SingleCare’s discount program. Zurzuvae is a brand-name drug and was approved by the U.S. Food and Drug Administration (FDA) in 2023.
The standard out-of-pocket cost of Zurzuvae without health insurance is $19,118.75 per 28, 25mg capsules though you can save using a SingleCare Zurzuvae coupon to pay only $17,125.17 for 28, 25mg capsules of Zurzuvae. If you don’t have access to an insurance plan, you can still use SingleCare for free Zurzuvae savings.
Each insurance formulary is different and may or may not cover Zurzuvae. The cost of Zurzuvae with insurance coverage varies depending on your plan - check with your insurance provider for specific drug coverage and copay details. If your insurance does not cover Zurzuvae, you can use SingleCare to get discounts on Zurzuvae at a participating pharmacy in the United States. Additionally, you can also use SingleCare coupons if you have Medicare or Medicaid. If Medicare or Medicaid don’t cover your Zurzuvae prescription, you can use SingleCare instead. Go to the SingleCare website or app to compare the lowest price of Zurzuvae with SingleCare versus your copay with insurance or Medicare.
Zurzuvae costs with Medicare will vary by plan, prescription, and coverage stage. Refer to your plan’s drug formulary to find out whether your Medicare Part D or Medicare Advantage plan covers Zurzuvae and how much the copay or coinsurance is. If Zurzuvae is not covered by Medicare or if you have not met your plan’s deductible, you may have to pay the full price of $19,118.75 for 28, 25mg capsules. In that case, using a SingleCare coupon for Zurzuvae could save you more money than Medicare. Our lowest price for Zurzuvae is currently $17,125.17 for 28, 25mg capsules.
Zurzuvae is a brand-name drug made by Biogen Idec. There is no generic version of Zurzuvae at this time. Use a SingleCare prescription drug discount card to pay $17,125.17 for 28, 25mg capsules.
Zurzuvae (zuranolone) is a prescription medicine used to treat postpartum depression (PPD) in adults. Postpartum depression is a type of depression that can happen after childbirth, causing symptoms like mood swings, extreme tiredness, and feelings of inadequacy. Zurzuvae can be used alone, or in combination with other antidepressant medication. It is generally taken once daily in the evening for up to 14 days and should be taken with food that contains fat. The exact way Zurzuvae works to treat postpartum depression (PPD) is not completely understood, but it is thought to work by enhancing the activity of GABAA receptors in the brain, which helps alleviate symptoms of PPD.
Zurzuvae is made by the pharmaceutical companies Sage Therapeutics and Biogen. It was approved by the U.S. Food and Drug Administration (FDA) in 2023.
Zurzuvae is a controlled substance, which means there is a potential for abuse and dependence. Tell your healthcare provider if you drink alcohol or have a substance use disorder.
Before taking Zurzuvae, tell your healthcare provider about all of your medical conditions, including if you have liver or kidney problems. Also, let your healthcare provider know if you are pregnant or breastfeeding. Because Zurzuvae may harm an unborn baby, women of reproductive age should use effective birth control while taking Zurzuvae and for some time (usually 7 days) after the last dose. You can talk to your healthcare provider about effective birth control that would be best for you.
Zurzuvae can interact with certain medications, so tell your healthcare professional about all the medications you take. This includes prescription and OTC drugs, vitamins, and supplements. You should avoid alcohol while taking Zurzuvae, as well as medications that cause dizziness or drowsiness.
Common side effects of Zurzuvae include drowsiness, dizziness, weakness, diarrhea, cold symptoms, and urinary tract infections.
Serious side effects may occur. If you have symptoms of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, get emergency medical help right away.
Zurzuvae can cause drowsiness and impaired coordination. You should avoid driving or performing other potentially dangerous activities for at least 12 hours after taking Zurzuvae, as you might not be able to judge your own ability to do them safely. Tell your healthcare provider if this medicine makes you feel excessively tired, like you cannot stay awake, or lightheaded.
Zurzuvae can also cause suicidal thoughts and behaviors. If you experience worsening depression, mood changes, or thoughts of suicide, contact your healthcare provider immediately or call the Suicide & Crisis Lifeline at 988.
This is not a full list of side effects, and others may occur. Consult your healthcare provider for more information and medical advice about side effects.
Zurzuvae differs from traditional antidepressants by targeting GABAA receptors in the brain, which may provide faster relief for postpartum depression (PPD) compared to standard antidepressants that affect serotonin or norepinephrine levels. Zurzuvae is specifically approved for PPD, which is especially helpful for new mothers. Consult your healthcare provider with questions and to determine if Zurzuvae is the right treatment for you.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
...SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2026 SingleCare Administrators. All rights reserved
© 2026 SingleCare Administrators. All rights reserved