Zurzuvae Coupons & Prices

      Controlled Substance

Zurzuvae is used to treat postpartum depression in adults. It is generally prescribed to be taken once a day in the evening for 14 days and should be taken with food that contains fat. The average retail price of Zurzuvae is $19,118.75 per 28, 25mg capsules, but patients can pay just $17,125.17 for 28, 25mg capsules of Zurzuvae with a card or coupon from SingleCare’s discount program. Zurzuvae is a brand-name drug and was approved by the U.S. Food and Drug Administration (FDA) in 2023.

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Zurzuvae coupon at Walgreens Pharmacy
$17128.17
$ 17,125
$3 off with signupwith signup

Show this free card to your pharmacist.

This coupon is not insurance.
Zurzuvae coupon at Publix Pharmacy
$17437.47
$ 17,434
$3 off with signupwith signup
Zurzuvae coupon at Kroger Pharmacy
$17639.84
$ 17,637
$3 off with signupwith signup
Zurzuvae coupon at Harris Teeter Pharmacy
$17639.84
$ 17,637
$3 off with signupwith signup
Zurzuvae coupon at Costco Pharmacy
$17845.21
$ 17,842
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 03/23/2026

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About Zurzuvae

      Controlled Substance

Zurzuvae is used to treat postpartum depression in adults. It is generally prescribed to be taken once a day in the evening for 14 days and should be taken with food that contains fat. The average retail price of Zurzuvae is $19,118.75 per 28, 25mg capsules, but patients can pay just $17,125.17 for 28, 25mg capsules of Zurzuvae with a card or coupon from SingleCare’s discount program. Zurzuvae is a brand-name drug and was approved by the U.S. Food and Drug Administration (FDA) in 2023.

About Zurzuvae

Zurzuvae is used to treat postpartum depression in adults. It is generally prescribed to be taken once a day in the evening for 14 days and should be taken with food that contains fat. The average retail price of Zurzuvae is $19,118.75 per 28, 25mg capsules, but patients can pay just $17,125.17 for 28, 25mg capsules of Zurzuvae with a card or coupon from SingleCare’s discount program. Zurzuvae is a brand-name drug and was approved by the U.S. Food and Drug Administration (FDA) in 2023.

Zurzuvae FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Zurzuvae cost without insurance?

The standard out-of-pocket cost of Zurzuvae without health insurance is $19,118.75 per 28, 25mg capsules though you can save using a SingleCare Zurzuvae coupon to pay only $17,125.17 for 28, 25mg capsules of Zurzuvae. If you don’t have access to an insurance plan, you can still use SingleCare for free Zurzuvae savings.

How much does Zurzuvae cost with insurance?

Each insurance formulary is different and may or may not cover Zurzuvae. The cost of Zurzuvae with insurance coverage varies depending on your plan - check with your insurance provider for specific drug coverage and copay details. If your insurance does not cover Zurzuvae, you can use SingleCare to get discounts on Zurzuvae at a participating pharmacy in the United States. Additionally, you can also use SingleCare coupons if you have Medicare or Medicaid. If Medicare or Medicaid don’t cover your Zurzuvae prescription, you can use SingleCare instead. Go to the SingleCare website or app to compare the lowest price of Zurzuvae with SingleCare versus your copay with insurance or Medicare.

Does Medicare cover Zurzuvae, and how much does it cost?

Zurzuvae costs with Medicare will vary by plan, prescription, and coverage stage. Refer to your plan’s drug formulary to find out whether your Medicare Part D or Medicare Advantage plan covers Zurzuvae and how much the copay or coinsurance is. If Zurzuvae is not covered by Medicare or if you have not met your plan’s deductible, you may have to pay the full price of $19,118.75 for 28, 25mg capsules. In that case, using a SingleCare coupon for Zurzuvae could save you more money than Medicare. Our lowest price for Zurzuvae is currently $17,125.17 for 28, 25mg capsules.

Is there a generic of Zurzuvae?

Zurzuvae is a brand-name drug made by Biogen Idec. There is no generic version of Zurzuvae at this time. Use a SingleCare prescription drug discount card to pay $17,125.17 for 28, 25mg capsules.

What is Zurzuvae? 

Zurzuvae (zuranolone) is a prescription medicine used to treat postpartum depression (PPD) in adults. Postpartum depression is a type of depression that can happen after childbirth, causing symptoms like mood swings, extreme tiredness, and feelings of inadequacy. Zurzuvae can be used alone, or in combination with other antidepressant medication. It is generally taken once daily in the evening for up to 14 days and should be taken with food that contains fat. The exact way Zurzuvae works to treat postpartum depression (PPD) is not completely understood, but it is thought to work by enhancing the activity of GABAA receptors in the brain, which helps alleviate symptoms of PPD.

Zurzuvae is made by the pharmaceutical companies Sage Therapeutics and Biogen. It was approved by the U.S. Food and Drug Administration (FDA) in 2023.

Zurzuvae is a controlled substance, which means there is a potential for abuse and dependence. Tell your healthcare provider if you drink alcohol or have a substance use disorder.

Before taking Zurzuvae, tell your healthcare provider about all of your medical conditions, including if you have liver or kidney problems. Also, let your healthcare provider know if you are pregnant or breastfeeding. Because Zurzuvae may harm an unborn baby, women of reproductive age should use effective birth control while taking Zurzuvae and for some time (usually 7 days) after the last dose. You can talk to your healthcare provider about effective birth control that would be best for you. 

Zurzuvae can interact with certain medications, so tell your healthcare professional about all the medications you take. This includes prescription and OTC drugs, vitamins, and supplements. You should avoid alcohol while taking Zurzuvae, as well as medications that cause dizziness or drowsiness. 

What are the side effects of Zurzuvae?

Common side effects of Zurzuvae include drowsiness, dizziness, weakness, diarrhea, cold symptoms, and urinary tract infections. 

Serious side effects may occur. If you have symptoms of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, get emergency medical help right away. 

Zurzuvae can cause drowsiness and impaired coordination. You should avoid driving or performing other potentially dangerous activities for at least 12 hours after taking Zurzuvae, as you might not be able to judge your own ability to do them safely. Tell your healthcare provider if this medicine makes you feel excessively tired, like you cannot stay awake, or lightheaded.

Zurzuvae can also cause suicidal thoughts and behaviors. If you experience worsening depression, mood changes, or thoughts of suicide, contact your healthcare provider immediately or call the Suicide & Crisis Lifeline at 988.

This is not a full list of side effects, and others may occur. Consult your healthcare provider for more information and medical advice about side effects.  

How is Zurzuvae different from other antidepressants?

Zurzuvae differs from traditional antidepressants by targeting GABAA receptors in the brain, which may provide faster relief for postpartum depression (PPD) compared to standard antidepressants that affect serotonin or norepinephrine levels. Zurzuvae is specifically approved for PPD, which is especially helpful for new mothers. Consult your healthcare provider with questions and to determine if Zurzuvae is the right treatment for you.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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Where are Zurzuvae coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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