Can Prozac cause weight loss?

Medically reviewed by Leslie Greenberg, MD

Board-Certified Family Physician

Updated Jan 12, 2026 • Published Jan 12, 2026

Fact Checked

Yes, Prozac can cause weight loss in some women. The medication may suppress appetite, leading to reduced food intake and weight loss, particularly during the first two to three months of treatment. Research cited in the article notes that appetite suppression often decreases over time, with appetite typically returning to normal within about six months.

Interested in learning more about Prozac and its side effects? Read our full analysis: What are the side effects of Prozac for women?

Medical disclaimer: This content is for general informational purposes only and does not constitute medical advice. Always consult your psychiatrist or other healthcare provider before making changes to your medication regimen.

Medically reviewed by Leslie Greenberg, MD

Board-Certified Family Physician

Leslie Greenberg, MD, is a board-certified practicing family physician with more than 25 years of doctoring experience. She was a psychology major at Northwestern University near Chicago, then graduated with an MD from the University of Nevada School of Medicine. She completed her family medicine residency at St. Joseph Hospital in Wichita, Kansas. She has trained more than 350 family medicine resident-physicians, been in private practice, and delivered babies for 22 years.

Written by Racheal Ede, Contributor

Racheal Ede is an experienced medical and health writer, with an extensive health background as a medical laboratory scientist.

Can Prozac cause weight loss?

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