Can metformin cause diarrhea?

Written by Ashley WongPharm. D.
Licensed Pharmacist
Updated Jan 23, 2026  •  Published Oct 28, 2025
Fact Checked

Digestive side effects are common with metformin, affecting up to 75% of people who take it. Diarrhea occurs more often with immediate-release metformin than with extended-release, appearing in 53.2% of immediate-release users compared with 10% of those taking the extended-release form. Ask your doctor about switching to metformin ER to manage diarrhea.

Want more info? Get tips for preventing and managing metformin diarrhea 

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Medical disclaimer: This content is for general informational purposes only and does not constitute medical advice. Always consult your endocrinologist or healthcare provider before making changes to your medication regimen.

Written by Ashley WongPharm. D.
Licensed Pharmacist

Ashley Wong, Pharm.D., has worked for healthcare companies where she translated complex drug information into easy-to-understand language for patients. She also served as a Senior Medical Information Specialist at a medical communications company, where she delivered clinically accurate drug information to healthcare providers and patients and compiled adverse event reports in accordance with the FDA's reporting guidelines.

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