Wellbutrin can help with anxiety in some people, but it is not FDA-approved for anxiety. It may be used off-label, especially in people who have both depression and anxiety, since studies show it can be similarly effective to SSRIs, though some individuals may experience anxiety as a side effect.
Wellbutrin is FDA-approved for depression, not anxiety, but it may be prescribed off-label for people who have both depression and anxiety when a healthcare provider determines it’s appropriate.
Research suggests Wellbutrin may reduce anxiety symptoms similarly to SSRIs in people with depression and anxiety, despite earlier concerns that it could worsen anxiety in some patients.
Wellbutrin is not safe for everyone, especially people with seizure disorders, eating disorders, or those stopping alcohol or certain medications abruptly.
Wellbutrin for anxiety |
|
|---|---|
| Category | Wellbutrin (bupropion) |
| Primary classification | Antidepressant (NDRI) |
| FDA-approved for anxiety | No (anxiety use is off-label) |
| When it may be used for anxiety | Often considered when someone has both depression and anxiety |
Want to learn more? Read our full analysis: Wellbutrin for anxiety: What you should know
Prescription resources
Wellbutrin (bupropion) is a prescription antidepressant available in immediate-release, sustained-release, and extended-release forms. If you’re prescribed Wellbutrin for depression or off-label for anxiety, SingleCare can help you compare pharmacy prices and find discounts on generic bupropion.
Medical disclaimer: This content is for general informational purposes only and does not constitute medical advice. Always consult your healthcare provider before making changes to your medication regimen.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
...Health education, drug info, wellness & more
SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2026 SingleCare Administrators. All rights reserved
© 2026 SingleCare Administrators. All rights reserved