Key takeaways
Proctofoam HC is a prescription rectal foam that costs about $274 without insurance for one 10-gram container.
Proctofoam HC does not have a generic equivalent, but prescription hydrocortisone-pramoxine creams may be lower-cost alternatives to Proctofoam.
Comparing pharmacy prices, using a prescription discount card, or asking about alternative treatments may help reduce the cost.
Proctofoam HC is a prescription rectal foam that helps relieve swelling and itching in the anal region. It contains pramoxine, a local anesthetic that numbs the affected area, and hydrocortisone, a corticosteroid that reduces swelling, redness, and itching. Proctofoam HC is typically applied to the affected area three or four times daily. Prescription discounts and lower-cost alternatives may help make treatment more affordable.
Is there a generic form of Proctofoam HC?
Products with the same ingredients as Proctofoam HC are available as generic hydrocortisone–pramoxine ointments, creams, lotions, or suppositories. As a rectal foam, there is no generic version of Proctofoam HC. Both pramoxine and hydrocortisone can also be purchased as separate OTC topical products.
Does insurance cover Proctofoam HC?
Some commercial insurance, Medicare Part D, and Medicaid plans may cover Proctofoam HC, while others may not. Coverage, formulary placement, and copay amounts vary by plan. Hydrocortisone-pramoxine alternatives may also be covered, depending on the specific product and insurance formulary. Contact the insurance provider or review the plan’s drug list for current coverage details.
How much does Proctofoam HC cost without insurance?
Without insurance, Proctofoam HC costs around $274 for one 10-gram container of 1% hydrocortisone acetate and 1% pramoxine hydrochloride foam. According to the Proctofoam HC prescribing information, each container delivers at least 14 applications. When used three to four times daily, one container provides about four days of treatment at roughly $70 per day. The prescribing information recommends discontinuing treatment if symptoms do not improve within two to three weeks or if the condition worsens.
People concerned about the cost can ask a healthcare professional about prescription hydrocortisone-pramoxine in other forms, such as creams and suppositories. Some OTC hemorrhoid medications contain hydrocortisone or a rectal anesthetic such as lidocaine. Ask a healthcare professional before switching treatments.
Compare Proctofoam HC prices to related drugs |
|||
|---|---|---|---|
| Drug name | Price without insurance of brand-name drug | SingleCare price | Savings options |
| Proctofoam HC (hydrocortisone/pramoxine HCl) | $274 per 1, 10 gm can of 1-1% foam | $186 per 1, 10 gm can of 1-1% foam of brand-name Proctofoam HC at Kroger | See latest prices |
| Analpram HC (hydrocortisone/pramoxine HCl) | $391 per 1, 30 gm tube of 2.5-1% cream | $267 per 1, 30 gm tube of 2.5-1% cream of brand-name Analpram HC at Kroger | See latest prices |
| Hydrocortisone-pramoxine cream | $214 per 1, 30 gm tube of 2.5-1% cream | $130 per 1, 30 gm tube of 2.5-1% cream of generic hydrocortisone-pramoxine at Kroger | See latest prices |
| Hydrocortisone 2.5% cream | $25 per 1, 30 gm of 2.5% cream | $5 per 1, 30 gm of 2.5% cream of generic hydrocortisone at Kroger | See latest prices |
| Pramoxine 1% lotion | $31 per 1, 237 mL bottle of 1% lotion | $22 per 1, 237 mL bottle of generic pramoxine at Kroger | See latest prices |
How to get Proctofoam HC without insurance
Proctofoam HC can be expensive for people without health insurance. People with insurance may also pay the full retail price if the medication is not included in their plan’s formulary. However, there are several ways to lower the cost of Proctofoam HC without insurance, including using a free SingleCare prescription discount card, comparing pharmacy prices, and asking about lower-cost alternatives.
1. Save around $90 with a SingleCare savings card
With a SingleCare coupon, Proctofoam HC may cost about $186 for one 10-gram container of 1%-1% foam, nearly $90 less than the average retail price of $274. Prices vary by pharmacy and location, so check the Proctofoam HC coupons page for current prices near you and review the FAQs for more savings and drug information.
SingleCare is free to use and available to everyone. Registered members can save even more, and it’s fast and free to join.
Save up to 80% on Proctofoam HC with SingleCare
Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.
2. Ask the prescriber about generic hydrocortisone-pramoxine
Generic formulations of hydrocortisone-pramoxine may be less costly. They are available as rectal creams or suppositories. A 30-gram tube of generic hydrocortisone-pramoxine costs an average of $214 at full retail and $130 at Kroger with a free SingleCare coupon. Generic hydrocortisone-pramoxine will require a prescription, so ask the prescriber for medical advice about switching to the generic. Hydrocortisone and pramoxine generics may also be prescribed separately.
3. Ask the prescribing healthcare provider about OTC versions
There is no exact OTC equivalent to Proctofoam. However, it may be possible to use an OTC hydrocortisone cream and an OTC rectal anesthetic such as Recticare (lidocaine) instead of prescription Proctofoam HC. These products may cost less, but there are trade-offs. OTC hydrocortisone cream is available only in strengths of 1% or less, and using too much lidocaine can cause serious side effects if the drug enters the bloodstream. Discuss these differences with the prescriber before switching treatments.
4. Shop for the lowest price
Prices for Proctofoam HC and prescription hydrocortisone-pramoxine alternatives vary by pharmacy. Compare prices in your area before filling the prescription, then check whether a SingleCare coupon is available at a lower price.
Lea este artículo en español aquí.
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Aug. 11, 2026. Prices vary by pharmacy. Visit our coupon page for updated drug prices at pharmacies near you.
- Proctofoam HC prescribing information, DailyMed (NIH National Library of Medicine) (2025)
- Proctofoam HC product monograph, Duchesnay Inc. (2015)
- Medically accurate: SingleCare’s Medical Review Board analyzes all of our content to confirm it’s in line with current medical advice.
- Evidence-based: Our content is sourced from reputable U.S.-based healthcare professionals and peer-reviewed research.
- Trustworthy: All of SingleCare’s content goes through a multi-phase review process by our writers, editors, and Medical Board in order to provide clear and credible information.