Key takeaways
Synthroid without insurance costs about $214 for a 90-day supply. Generic levothyroxine and SingleCare coupons can bring the price down to as low as $10.
Generic levothyroxine works the same as brand-name Synthroid. Most insurance plans prefer to cover the generic.
SingleCare coupons work for both brand-name and generic Synthroid. Patients who must stay on the brand-name version can still save.
Synthroid (levothyroxine sodium) is a prescription thyroid hormone that treats an underactive thyroid gland (hypothyroidism) or slows the growth of thyroid cancer. There are no over-the-counter substitutes for prescription thyroid hormones, but patients can save money by switching to generic Synthroid, using a SingleCare discount card, comparing pharmacy prices, or exploring other savings strategies.
RELATED: What is Synthroid
How much does Synthroid cost without insurance?
Synthroid prices average $214 for a 90-day supply of 75 mcg tablets, or a little over $2 per tablet. Health insurance can help cover much of this cost, but copays and other out-of-pocket costs vary by insurance plan and its formulary.
Switching to generic Synthroid or another brand-name version of levothyroxine can lead to significant savings. Discount coupons can also help reduce the cost of Synthroid and its alternatives.
How much does generic Synthroid cost?
Switching to generic Synthroid (levothyroxine) can significantly reduce out-of-pocket costs. The price of levothyroxine without insurance is about $71 for 90, 75 mcg tablets. With a SingleCare savings card, the cost of levothyroxine can drop to as low as $10 at Walmart. In some cases, a healthcare provider may prescribe another brand-name alternative to Synthroid, such as Levoxyl, Tirosint, or Unithroid. Prices vary across these medications.
RELATED: Discount prescriptions with SingleCare
Compare Synthroid prices to related drugs |
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|---|---|---|---|
| Drug name | Price without insurance | SingleCare price | Savings options |
| Synthroid | $214 per 90, 75 mcg tablets | $155 per 90, 75 mcg tablets at Kroger | See latest prices |
| Generic Synthroid (levothyroxine) | $71 per 90, 75 mcg tablets of generic Synthroid | $10 per 90, 75 mcg tablets of at Walmart | See latest prices |
| Unithroid (levothyroxine) | $488 per 90, 75 mcg tablets | $13 per 90, 75 mcg tablets at Kroger | See latest prices |
| Levoxyl (levothyroxine) | $124 per 90, 75 mcg tablets | $13 per 90, 75 mcg tablets at Kroger | See latest prices |
| Tirosint (levothyroxine) | $217 per 30, 50 mcg capsules | $153 per 30, 50 mcg capsules at Kroger | See latest prices |
RELATED: Tirosint vs. Synthroid: differences, similarities & side effects
Synthroid costs by dose
Doses of Synthroid are very small and may change several times throughout thyroid replacement treatment. As a general rule, the retail price does not vary based on dosage strength. Pricing differences come down to whether the prescription is filled as brand-name or generic and which pharmacy fills it. Brand-name Synthroid runs about $155 for 90 tablets at most strengths with a SingleCare coupon, while generic levothyroxine drops to about $10. Pricing shifts slightly at the 300 mcg strength.
Compare Synthroid prices by strength |
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|---|---|---|
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(per 90 tablets) |
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| Strength | SingleCare price (brand-name) | Singdepend on (generic) |
| 25 mcg | $155 at Kroger | $a 10 at Walmart |
| 50 mcg | $155 at Kroger | $10 at Walmart |
| 75 mcg | $155 at Kroger | $10 at Walmart |
| 88 mcg | $155 at Kroger | $10 at Walmart |
| 100 mcg | $155 at Kroger | $10 at Walmart |
| 112 mcg | $155 at Kroger | $10 at Walmart |
| 125 mcg | $155 at Kroger | $10 at Walmart |
| 137 mcg | $155 at Kroger | $10 at Walmart |
| 150 mcg | $155 at Kroger | $10 at Walmart |
| 175 mcg | $155 at Kroger | $10 at Walmart |
| 200 mcg | $155 at Kroger | $10 at Walmart |
| 300 mcg | $155 at Harris Teeter | $29 at Kroger |
Is Synthroid covered by insurance?
Many health insurance plans cover Synthroid with a valid prescription, including Medicare Part D and Medicaid. As a brand-name medication, Synthroid is typically covered as a higher-tier drug. Most plans prefer to cover levothyroxine sodium, the generic version of Synthroid.
RELATED: Does Medicare cover Synthroid?
How to get Synthroid covered by insurance
Most health insurance plans cover a Synthroid prescription, but some do not. Even when Synthroid is covered, the insurance company may require prior authorization before approving the brand-name version over the generic. Generic levothyroxine is widely covered, so switching to the generic drug is often an option for patients who run into coverage issues. If the brand-name version is not covered, patients can ask for a formulary exception, which requires the prescriber to file paperwork with the patient’s health insurance provider to justify the prescription.
How to get Synthroid without insurance
Synthroid can be challenging to pay for over the long-term, especially for people without health insurance coverage. Manufacturer coupons, patient assistance programs, and manufacturer savings cards may help, though they usually have strict eligibility criteria. A more reliable way to save is to use a SingleCare discount card.
1. Use SingleCare’s prescription savings program
Enter your ZIP code on SingleCare’s Synthroid discount coupon page to find the lowest price at pharmacies near you. Present the coupon at the pharmacy counter to receive the discount.
Save up to 80% on Synthroid with SingleCare
Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.
2. Ask a healthcare provider about generic Synthroid
Generic levothyroxine is usually less expensive than brand-name Synthroid. However, there may be reasons why a healthcare provider prescribes brand-name Synthroid or a specific levothyroxine product, so ask the prescriber about the most appropriate option.
3. Compare prices
Prescription drug pricing varies between pharmacies, so price-shopping can lead to meaningful savings on a 90-day supply of Synthroid. The manufacturer’s Synthroid Delivers program is another option, offering consistent pricing and mail-order delivery directly from AbbVie.
4. Visit a community health clinic
Community health clinics can be a helpful resource for patients who are having trouble affording generic or brand-name Synthroid. Some clinics provide low-cost or free medical care, including prescription drugs, to eligible patients. Contact your city or county health department for help locating community health clinics, medical programs, and low-cost health insurance resources in your area.
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Jun. 3, 2026. Prices vary by pharmacy. Visit our coupon page for updated drug prices at pharmacies near you.
- Hypothyroidism, StatPearls
- Synthroid levothyroxine sodium tablet prescription drug information, DailyMed (NIH National Library of Medicine)
- Medically accurate: SingleCare’s Medical Review Board analyzes all of our content to confirm it’s in line with current medical advice.
- Evidence-based: Our content is sourced from reputable U.S.-based healthcare professionals and peer-reviewed research.
- Trustworthy: All of SingleCare’s content goes through a multi-phase review process by our writers, editors, and Medical Board in order to provide clear and credible information.