Angiotensin receptor/neprilysin inhibitors: Uses, common brands, and safety info

Key takeaways

• Entresto is the only angiotensin receptor/neprilysin inhibitor (ARNI) currently available in pharmacies. It contains two ingredients: valsartan and sacubitril.

• Entresto can be used in addition to other medicines to reduce the risk of hospitalization and death in adults with certain types of heart failure. It is also used in children one year and older to treat certain types of heart failure. 

• Common side effects include low blood pressure, high potassium, cough, and dizziness. Entresto should not be taken by certain individuals, such as those who have had a previous allergic reaction to an ACE inhibitor or ARB, or those who are pregnant or breastfeeding.

• Consult your healthcare provider for more information and medical advice about your condition and treatment.