Prilosec Coupons & Prices

Omeprazole

Prilosec is a prescription and over-the-counter combination drug that treats duodenal and gastric ulcers (sores) as well as GERD (gastroesophageal reflux disease) by reducing and neutralizing stomach acid. The retail price for Prilosec is $553.58 per 30, 10mg packets, but a SingleCare Prilosec coupon reduces the price of generic Prilosec to $5.78 for 30, 40mg capsules delayed release at major retailers, pharmacies, and supermarkets.

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Prilosec coupon at Kroger Pharmacy
$8.78
$ 5.78
$3 off with signupwith signup

Show this free card to your pharmacist.

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Prilosec coupon at Harris Teeter Pharmacy
$8.78
$ 5.78
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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and it's free to join

Prilosec coupon at Food Lion Pharmacy
$ 13.70
Prilosec coupon at Walgreens Pharmacy
$18.23
$ 15.23
$3 off with signupwith signup
Prilosec coupon at Costco Pharmacy
$ 16.66
Prilosec coupon at Publix Pharmacy
$21.00
$ 18.00
$3 off with signupwith signup
$25.23
$ 22.23
$3 off with signupwith signup
$ 23.59
$ 23.59

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Prilosec

Prilosec is a prescription and over-the-counter combination drug that treats duodenal and gastric ulcers (sores) as well as GERD (gastroesophageal reflux disease) by reducing and neutralizing stomach acid. The retail price for Prilosec is $553.58 per 30, 10mg packets, but a SingleCare Prilosec coupon reduces the price of generic Prilosec to $5.78 for 30, 40mg capsules delayed release at major retailers, pharmacies, and supermarkets.

Prilosec Price History & Information

Price History for Prilosec

30 count, packet, 10mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Prilosec

30 count, packet, 10mg
PharmacyPrilosec Retail PricePrilosec SingleCare Price
Walmart$543.00$480.60
Walgreens$548.10$481.80
Kroger Pharmacy$543.00$447.60

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Prilosec

Prilosec is a prescription and over-the-counter combination drug that treats duodenal and gastric ulcers (sores) as well as GERD (gastroesophageal reflux disease) by reducing and neutralizing stomach acid. The retail price for Prilosec is $553.58 per 30, 10mg packets, but a SingleCare Prilosec coupon reduces the price of generic Prilosec to $5.78 for 30, 40mg capsules delayed release at major retailers, pharmacies, and supermarkets.

Prilosec FAQs

How much does Prilosec cost without insurance?

You will pay an average of $553.58 for 30, 10mg packets of Prilosec without insurance, but only $5.78 per 30, 40mg capsules delayed release of generic Prilosec with a SingleCare Prilosec coupon.

How much does Prilosec cost with insurance?

Prilosec copay costs may vary depending on your insurance plan and the format prescribed. Over-the-counter Prilosec may not be covered by your health insurance. With SingleCare, generic Prilosec costs $5.78 per 30, 40mg capsules delayed release, so you should ask your pharmacist to compare your SingleCare price with your insurance Prilosec copay. A SingleCare discount card typically saves you up to 80% off on your prescription drugs, which may be lower than your copay.

Does Medicare cover Prilosec and how much does it cost?

Prilosec is usually not covered by Medicare prescription drug plans, but the generic version of Prilosec, omeprazole, is covered as a tablet, capsule, or oral solution. For patients without coverage, consider bringing your SingleCare Prilosec coupon to your pharmacist. With a SingleCare savings card, the price of generic Prilosec is only $5.78 30, 40mg capsules delayed release.

Is there a generic of Prilosec?

Prilosec is a brand-name prescription and over-the-counter drug and is available in both formulations as generic omeprazole. Over-the-counter omeprazole is widely available from generic brands such as Up & Up, Walgreens, Equate, and others. Generic prescription Prilosec is supplied by Apotex, Dr. Reddy's, Glenmark, Mylan, and dozens of other generic manufacturers.

What is Prilosec?

Prilosec (omeprazole) is a brand-name prescription and over-the-counter drug that treats gastric or duodenal ulcers, which are sores that form in the stomach (gastric ulcers) or at the place where the small intestine connects to the stomach (the duodenum). Prilosec is also used to relieve gastrointestinal reflux disease (GERD).

Gastic and duodenal ulcers are caused by a bacterial infection that changes the mucus that protects the stomach and duodenum linings from stomach acid. Without this protection, stomach acid irritates and damages the stomach and intestinal tissues. For ulcers, Prilosec is frequently prescribed with antibiotics (clarithromycin, amoxicillin) to control the underlying bacterial infection.

GERD is a condition in which stomach acid washes back into the esophagus, causing pain, burning, and discomfort.

Omeprazole is an “acid reducer” belonging to a class of drugs called proton-pump inhibitors. It blocks the production of acid by the stomach, and so reduces stomach acid.

Prilosec is taken as a capsule or oral suspension. Ulcers will typically take four to eight weeks to heal. GERD symptoms should subside in four weeks.

What are the side effects of Prilosec?

The most common side effects of Prilosec are stomach pain, nausea, diarrhea, headache, fever, cold symptoms, constipation, and gas. The most serious but rare side effects of Prilosec are low magnesium, kidney problems, and seizures. Allergic reactions are rare. Seek medical help if you notice signs of an allergic reaction such as hives, rash, trouble breathing, or facial swelling. This is not a complete list of possible side effects. Ask your doctor or pharmacist about possible side effects before taking this medicine.

Where are Prilosec coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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