Prilosec is a prescription and over-the-counter combination drug that treats duodenal and gastric ulcers (sores) as well as GERD (gastroesophageal reflux disease) by reducing and neutralizing stomach acid. The retail price for Prilosec is $553.58 per 30, 10mg packets, but a SingleCare Prilosec coupon reduces the price of generic Prilosec to $5.78 for 30, 40mg capsules delayed release at major retailers, pharmacies, and supermarkets.
Edit your dosage
14 capsule delayed release, 10mgEdit
Unlock members-only prices.Free signup.
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.

Save an extra $3 on any eligible prescription! Sign up for free
Members can save even more
and it's free to join
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
Members save the most
Prilosec is a prescription and over-the-counter combination drug that treats duodenal and gastric ulcers (sores) as well as GERD (gastroesophageal reflux disease) by reducing and neutralizing stomach acid. The retail price for Prilosec is $553.58 per 30, 10mg packets, but a SingleCare Prilosec coupon reduces the price of generic Prilosec to $5.78 for 30, 40mg capsules delayed release at major retailers, pharmacies, and supermarkets.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Prilosec Retail Price | Prilosec SingleCare Price |
|---|---|---|
| Walmart | $543.00 | $480.60 |
| Walgreens | $548.10 | $481.80 |
| Kroger Pharmacy | $543.00 | $447.60 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Prilosec is a prescription and over-the-counter combination drug that treats duodenal and gastric ulcers (sores) as well as GERD (gastroesophageal reflux disease) by reducing and neutralizing stomach acid. The retail price for Prilosec is $553.58 per 30, 10mg packets, but a SingleCare Prilosec coupon reduces the price of generic Prilosec to $5.78 for 30, 40mg capsules delayed release at major retailers, pharmacies, and supermarkets.
You will pay an average of $553.58 for 30, 10mg packets of Prilosec without insurance, but only $5.78 per 30, 40mg capsules delayed release of generic Prilosec with a SingleCare Prilosec coupon.
Prilosec copay costs may vary depending on your insurance plan and the format prescribed. Over-the-counter Prilosec may not be covered by your health insurance. With SingleCare, generic Prilosec costs $5.78 per 30, 40mg capsules delayed release, so you should ask your pharmacist to compare your SingleCare price with your insurance Prilosec copay. A SingleCare discount card typically saves you up to 80% off on your prescription drugs, which may be lower than your copay.
Prilosec is usually not covered by Medicare prescription drug plans, but the generic version of Prilosec, omeprazole, is covered as a tablet, capsule, or oral solution. For patients without coverage, consider bringing your SingleCare Prilosec coupon to your pharmacist. With a SingleCare savings card, the price of generic Prilosec is only $5.78 30, 40mg capsules delayed release.
Prilosec is a brand-name prescription and over-the-counter drug and is available in both formulations as generic omeprazole. Over-the-counter omeprazole is widely available from generic brands such as Up & Up, Walgreens, Equate, and others. Generic prescription Prilosec is supplied by Apotex, Dr. Reddy's, Glenmark, Mylan, and dozens of other generic manufacturers.
Prilosec (omeprazole) is a brand-name prescription and over-the-counter drug that treats gastric or duodenal ulcers, which are sores that form in the stomach (gastric ulcers) or at the place where the small intestine connects to the stomach (the duodenum). Prilosec is also used to relieve gastrointestinal reflux disease (GERD).
Gastic and duodenal ulcers are caused by a bacterial infection that changes the mucus that protects the stomach and duodenum linings from stomach acid. Without this protection, stomach acid irritates and damages the stomach and intestinal tissues. For ulcers, Prilosec is frequently prescribed with antibiotics (clarithromycin, amoxicillin) to control the underlying bacterial infection.
GERD is a condition in which stomach acid washes back into the esophagus, causing pain, burning, and discomfort.
Omeprazole is an “acid reducer” belonging to a class of drugs called proton-pump inhibitors. It blocks the production of acid by the stomach, and so reduces stomach acid.
Prilosec is taken as a capsule or oral suspension. Ulcers will typically take four to eight weeks to heal. GERD symptoms should subside in four weeks.
The most common side effects of Prilosec are stomach pain, nausea, diarrhea, headache, fever, cold symptoms, constipation, and gas. The most serious but rare side effects of Prilosec are low magnesium, kidney problems, and seizures. Allergic reactions are rare. Seek medical help if you notice signs of an allergic reaction such as hives, rash, trouble breathing, or facial swelling. This is not a complete list of possible side effects. Ask your doctor or pharmacist about possible side effects before taking this medicine.
SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2025 SingleCare Administrators. All rights reserved
© 2025 SingleCare Administrators. All rights reserved