Esomeprazole Magnesium is a commonly used stomach acid reducer that treats heartburn (over-the-counter Esomeprazole Magnesium) or serious medical problems like GERD, ulcers, esophagitis, or excessive stomach acid production (prescription Esomeprazole Magnesium). The average pharmacy price of a 90-day supply of prescription Esomeprazole Magnesium is $780.11 per 90, 40mg capsules delayed release. With SingleCare, the lowest price for Esomeprazole Magnesium is $20.89 for 90, 40mg capsules delayed release.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Esomeprazole Magnesium is a commonly used stomach acid reducer that treats heartburn (over-the-counter Esomeprazole Magnesium) or serious medical problems like GERD, ulcers, esophagitis, or excessive stomach acid production (prescription Esomeprazole Magnesium). The average pharmacy price of a 90-day supply of prescription Esomeprazole Magnesium is $780.11 per 90, 40mg capsules delayed release. With SingleCare, the lowest price for Esomeprazole Magnesium is $20.89 for 90, 40mg capsules delayed release.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Nexium Retail Price | Esomeprazole Magnesium Retail Price | Esomeprazole Magnesium SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $960.30 | $667.27 | $99.00 |
| Walmart | - | $273.30 | $63.12 |
| Walgreens | $963.00 | $515.70 | $253.80 |
| Kroger Pharmacy | $1042.20 | $745.39 | $24.30 |
| Albertsons Pharmacy | - | $639.00 | $60.30 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Esomeprazole Magnesium is a commonly used stomach acid reducer that treats heartburn (over-the-counter Esomeprazole Magnesium) or serious medical problems like GERD, ulcers, esophagitis, or excessive stomach acid production (prescription Esomeprazole Magnesium). The average pharmacy price of a 90-day supply of prescription Esomeprazole Magnesium is $780.11 per 90, 40mg capsules delayed release. With SingleCare, the lowest price for Esomeprazole Magnesium is $20.89 for 90, 40mg capsules delayed release.
Generic Esomeprazole Magnesium costs $20.89 for 90, 40mg capsules delayed release with a free Esomeprazole Magnesium coupon from SingleCare. But, you could lower this cost more depending on your prescription details. Use the dropdown menu above to update your prescription information (i.e., brand/generic, quantity, form, dosage) to get the most accurate prices of Esomeprazole Magnesium with SingleCare near you.
Without insurance coverage, the average cash price of Esomeprazole Magnesium is $780.11 for 90, 40mg capsules delayed release. Retail Esomeprazole Magnesium prices can vary by pharmacy, particularly for OTC Esomeprazole Magnesium. Instead of paying full price for Esomeprazole Magnesium, use a SingleCare Esomeprazole Magnesium coupon without insurance to lower the price of Esomeprazole Magnesium to as little as $20.89 for 90, 40mg capsules delayed release.
Prescription Esomeprazole Magnesium coverage varies by health plan, but OTC Esomeprazole Magnesium is almost never covered. When prescription Esomeprazole Magnesium is covered, the copay cost will vary based on the formulary. If coverage is denied or the out-of-pocket cost is high, use a SingleCare Esomeprazole Magnesium coupon. The lowest SingleCare Esomeprazole Magnesium price is $20.89 for 90, 40mg capsules delayed release.
Medicare drug plans typically cover prescription Esomeprazole Magnesium but do not cover the over-the-counter version. The out-of-pocket cost may be higher than usual because many plans place Esomeprazole Magnesium in their higher copay tiers. With a SingleCare discount coupon, the lowest price of Esomeprazole Magnesium is $20.89 for 90, 40mg capsules delayed release.
Medicaid coverage for Esomeprazole Magnesium varies by state and may include nonprescription Esomeprazole Magnesium. The out-of-pocket cost should be minimal, but there may be restrictions. Instead of Medicaid, a free coupon for Esomeprazole Magnesium from SingleCare can lower the price of Esomeprazole Magnesium to $20.89 for 90, 40mg capsules delayed release.
The brand-name version of prescription Esomeprazole Magnesium is Nexium. The brand-name version of over-the-counter Esomeprazole Magnesium is Nexium 24HR. Generic OTC Esomeprazole Magnesium is frequently packaged as “Acid Reducer.” These drugs can be purchased at a reduced price through SingleCare’s discount program.
Esomeprazole Magnesium is a lower-priced generic prescription drug. Comparing pharmacy prices can help you save money by finding the lowest price for Esomeprazole Magnesium. However, Esomeprazole Magnesium can be purchased for only $20.89 for 90, 40mg capsules delayed release with SingleCare’s savings program. Bonus savings on future refills or new prescription drugs can be earned by joining SingleCare’s bonus loyalty program.
Other ways of saving include enrolling in Medicaid or Medicare Part D Extra Help. Community resources are also available, including 340B clinics or hospitals that could sell Esomeprazole Magnesium at a government-subsidized price.
Both pantoprazole and omeprazole are proton pump inhibitors (PPIs) like esomeprazole, but the retail prices of the prescription versions are lower than Esomeprazole Magnesium. Other prescription medications that reduce stomach acid are H2 blockers like cimetidine and famotidine. They are often the cheapest prescription stomach acid reducers, but side effects may be different. Ask a healthcare professional before switching.
The cheapest alternative to prescription Esomeprazole Magnesium is any of the over-the-counter versions, but these may not be as effective. Ask a healthcare provider for advice. Generic versions of these drugs are comparably priced to each other, though the brand-name versions are slightly more expensive. Most can be purchased at a discount when using a SingleCare savings card at a participating pharmacy.
SingleCare is accepted at most major pharmacies and grocers, i.e., Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Esomeprazole Magnesium coupon to your mobile wallet and show your pharmacist when you pick up your prescription.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved