What is Abilify Maintena: Uses, Warnings & Interactions

Updated May 6, 2025  •  Published Dec 30, 2020

Abilify Maintena overview

BRAND NAMES:

  • Abilify Maintena Dual-Chambered Syringe, Abilify Maintena Vial

Generic Names:

  • Abilify Maintena

Uses:

  • Treats schizophrenia, and agitation caused by schizophrenia or bipolar disorder.

Therapeutic Classes:

  • Antipsychotic

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Abilify Maintena used for?

What form(s) does Abilify Maintena come in

  • Injectable

What are common Abilify Maintena doses?

  • Prefilled Syringe 300MG

  • Prefilled Syringe 400MG

  • Suspension Reconstituted Er 300MG

  • Suspension Reconstituted Er 400MG

Common Abilify Maintena prescriptions

  • Abilify Maintena
    300mg prefilled syringe

  • Abilify Maintena
    400mg prefilled syringe

  • Abilify Maintena
    300mg suspension reconstituted er

  • Abilify Maintena
    400mg suspension reconstituted er

How to take Abilify Maintena

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.

  • Injection routeA nurse or other health provider will give you this medicine.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: This medicine needs to be given on a fixed schedule. Injection routeCall your doctor or pharmacist for instructions.

  • Injection routeA nurse or other health provider will give you this medicine.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.

  • Missed dose: This medicine needs to be given on a fixed schedule. Injection routeCall your doctor or pharmacist for instructions.

What to do if you miss a dose of Abilify Maintena

Abilify Maintena contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to aripiprazole.

Abilify Maintena warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have diabetes, heart failure, heart or blood vessel disease, heart rhythm problems, high or low blood pressure, high cholesterol, or a history of seizures, heart attack, or stroke.

  • For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.

  • This medicine may cause the following problems: Neuroleptic malignant syndrome (NMS), a neurologic disorder than can be life-threateningTardive dyskinesia (movement disorder that may become permanent)Changes in blood sugar levelsUnusual changes in behavior, such as gambling urges, binge or compulsive eating, compulsive shopping, or sexual urges

  • This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel lightheaded or dizzy.

  • You may get overheated more easily while you are receiving this medicine. Be careful when you exercise or you are outside in hot or humid weather. Drink plenty of water to stay hydrated.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Lightheadedness, dizziness, fainting

  • Seizures

  • Unusual moods or behavior, thoughts of hurting yourself

  • Unusual tiredness or sleepiness

Abilify Maintena interactions

  • Some medicines can affect how aripiprazole works. Tell your doctor if you are using any of the following: Carbamazepine, clarithromycin, fluoxetine, itraconazole, ketoconazole, paroxetine, quinidine, or rifampinBenzodiazepine or sedative medicine (including lorazepam)Blood pressure medicine

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • Do not drink alcohol while you are using this medicine.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel lightheaded or dizzy.

  • You may get overheated more easily while you are receiving this medicine. Be careful when you exercise or you are outside in hot or humid weather. Drink plenty of water to stay hydrated.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Abilify Maintena side effects

Serious Side Effects

  • Lightheadedness, dizziness, fainting

  • Unusual tiredness or sleepiness

  • Increased hunger or thirst, change in how much or how often you urinate

  • Seizures

  • Sweating, uneven heartbeat, muscle stiffness

  • Confusion, unusual behavior, depressed mood, or thoughts of hurting yourself or others

  • Jerky muscle movements that you cannot control (often in your face, tongue, or jaw)

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Anxiety, irritability, nervousness, restlessness, trouble sleeping

  • Compulsive behavior or intense urges you cannot control

  • Fever, chills, cough, sore throat, body aches

Less Serious Side Effects

  • Unusual weight gain

  • Headache

  • Nausea, vomiting

  • Redness, pain, swelling, or itching where the shot was given

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