What is Acetazolamide Sodium: Uses, Warnings & Interactions

Updated May 6, 2025  •  Published Dec 30, 2020

Acetazolamide Sodium overview

BRAND NAMES:

  • acetaZOLAMIDE

Generic Names:

  • Acetazolamide

Uses:

  • Treats glaucoma, epilepsy, mountain sickness, and edema (swelling).

Therapeutic Classes:

  • Anticonvulsant, Antiglaucoma, Cardiovascular Agent, Musculoskeletal Agent, Renal-Urologic Agent, Urinary Stone Agent

Forms:

  • Tablet, Long Acting Capsule

How it’s taken:

  • By mouth

What is Acetazolamide Sodium used for?

What form(s) does Acetazolamide Sodium come in

  • Tablet

  • Long Acting Capsule

What are common Acetazolamide Sodium doses?

  • Tablet 125MG

  • Tablet 250MG

  • Bottle 25GM of

  • Bottle 100GM of

Common Acetazolamide Sodium prescriptions

  • acetaZOLAMIDE
    125mg tablet

  • acetaZOLAMIDE
    250mg tablet

How to take Acetazolamide Sodium

  • Your doctor will tell you how much to use and how often.

  • Use this medicine exactly as your doctor ordered.

  • May be taken with or without food.

  • Swallow the extended-release capsule whole. Do not chew, crush, or open.

  • You will need to go to the bathroom more often while you are taking this medicine. To keep from having to go too often during the night, take this medicine in the morning. If you use more than 1 dose a day, take your last dose before 6 p.m. (unless your doctor tells you differently).

  • You will need to go to the bathroom more often while you are taking this medicine. To keep from having to go too often during the night, take this medicine in the morning. If you use more than 1 dose a day, take your last dose before 6 p.m. (unless your doctor tells you differently).

  • Swallow the extended-release capsule whole. Do not chew, crush, or open.

  • Your doctor will tell you how much to use and how often.

  • Use this medicine exactly as your doctor ordered.

  • May be taken with or without food.

What to do if you miss a dose of Acetazolamide Sodium

  • You should not use two doses at the same time.

  • Use the missed dose as soon as you remember.

  • If it is almost time for your next dose, wait until then to use your medicine and skip the missed dose.

Acetazolamide Sodium contraindications

  • You should not use this medicine if you have had an allergic reaction to acetazolamide or related medicine such as methazolamide (Neptazane®) or dichlorphenamide (Daranide®).

Acetazolamide Sodium warnings

  • Check with your doctor before taking if you have lung, kidney, or liver disease, diabetes, gout, or a poorly working adrenal gland (Addison's disease).

  • Talk with your doctor before use if you are pregnant or breastfeeding.

  • If you use acetazolamide for seizures, do not stop taking this medicine suddenly. You may need to use smaller and smaller doses before completely stopping the medicine.

  • Acetazolamide can make you dizzy or drowsy. Be careful if you drive a car or operate machinery.

  • You may need to eat or drink foods containing potassium, such as citrus juices, oranges, or bananas, to prevent potassium loss while taking this medicine - check with your doctor.

  • This medicine may increase the level of sugar in your blood or urine, which can worsen diabetes.

  • Severe nausea or vomiting

  • Unusual bleeding or bruising

  • Pain in joints or lower back

Acetazolamide Sodium interactions

  • Make sure your doctor knows if you are taking aspirin, amphetamines (Dexedrine®), quinidine, or methenamine (Mandelamine®).

  • Talk with your doctor before use if you are pregnant or breastfeeding.

  • If you use acetazolamide for seizures, do not stop taking this medicine suddenly. You may need to use smaller and smaller doses before completely stopping the medicine.

  • Acetazolamide can make you dizzy or drowsy. Be careful if you drive a car or operate machinery.

  • You may need to eat or drink foods containing potassium, such as citrus juices, oranges, or bananas, to prevent potassium loss while taking this medicine - check with your doctor.

  • This medicine may increase the level of sugar in your blood or urine, which can worsen diabetes.

Acetazolamide Sodium side effects

Serious Side Effects

  • Unusual bleeding or bruising

  • Severe nausea or vomiting

  • Pain in joints or lower back

  • Irregular heartbeat

  • Trouble breathing

  • Skin rash, hives, or itching

  • Painful urination

  • Bloody stools or urine

  • Yellowing of skin or eyes

Less Serious Side Effects

  • Vision changes

  • Frequent urination

  • Dizziness, drowsiness, or lightheadedness

  • Numbness or tingling in hands, feet, or mouth

  • Nausea, vomiting, or diarrhea

  • Appetite loss or a metallic taste in mouth