Actemra is an FDA-approved brand-name prescription drug used to treat rheumatoid arthritis, certain types of juvenile idiopathic arthritis, giant cell arteritis (inflammation of the arteries), and cytokine release syndrome. In all these conditions, the body's immune system mistakenly attacks cells in the joints or blood vessels, causing swelling, stiffness, and pain. The active ingredient in Actemra, tocilizumab, suppresses the immune system and “slows down” the body's attack on the joints and blood vessels. Actemra is classified as an interleukin-6 (IL-6) receptor antagonist. Actemra is usually administered by a healthcare professional, but a self-injecting Actemra pen is available by prescription. Actemra costs $6,453.57 at full price. A SingleCare Actemra coupon reduces that price to $2,599.39.
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Prices updated: 03/24/2026
Actemra is an FDA-approved brand-name prescription drug used to treat rheumatoid arthritis, certain types of juvenile idiopathic arthritis, giant cell arteritis (inflammation of the arteries), and cytokine release syndrome. In all these conditions, the body's immune system mistakenly attacks cells in the joints or blood vessels, causing swelling, stiffness, and pain. The active ingredient in Actemra, tocilizumab, suppresses the immune system and “slows down” the body's attack on the joints and blood vessels. Actemra is classified as an interleukin-6 (IL-6) receptor antagonist. Actemra is usually administered by a healthcare professional, but a self-injecting Actemra pen is available by prescription. Actemra costs $6,453.57 at full price. A SingleCare Actemra coupon reduces that price to $2,599.39.
Actemra is an FDA-approved brand-name prescription drug used to treat rheumatoid arthritis, certain types of juvenile idiopathic arthritis, giant cell arteritis (inflammation of the arteries), and cytokine release syndrome. In all these conditions, the body's immune system mistakenly attacks cells in the joints or blood vessels, causing swelling, stiffness, and pain. The active ingredient in Actemra, tocilizumab, suppresses the immune system and “slows down” the body's attack on the joints and blood vessels. Actemra is classified as an interleukin-6 (IL-6) receptor antagonist. Actemra is usually administered by a healthcare professional, but a self-injecting Actemra pen is available by prescription. Actemra costs $6,453.57 at full price. A SingleCare Actemra coupon reduces that price to $2,599.39.
At most pharmacies, the full cost of Actemra will be $6,453.57. That same prescription will cost $2,599.39 per 1, 20ml of 400mg/20ml vial using a SingleCare savings card, which you can use at specialty and participating pharmacies. However, Actemra is usually injected by a healthcare professional and is only available in pharmacies as a pen injection.
The copay cost of Actemra varies greatly depending on your health insurance plan and the dose prescribed. With SingleCare, Actemra costs. Ask your pharmacist to compare that SingleCare cost to your copay so that you get the best deal on your prescription.
Medicare Advantage and Medicare Part D prescription drug insurance plans usually do not provide coverage for Actemra. Actemra is most often injected by a healthcare provider, so Actemra will be covered under Medicare Part B. If you have a prescription for Actemra, consider using a SingleCare Actemra coupon for your prescription. With SingleCare, the price of Actemra is $2,599.39 for 1, 20ml of 400mg/20ml vial.
Actemra is a brand-name prescription drug with the active ingredient tocilizumab. Generic tocilizumab is not available at this time.
Actemra is a brand-name prescription medication used to treat active rheumatoid arthritis, certain types of juvenile idiopathic arthritis, and giant cell arteritis, a painful condition in which the arteries swell up, particularly the arteries at the top of the head. It can also treat cytokine release syndrome. These are all conditions in which the body's immune system mistakenly attacks tissues in the joints or arteries as if they were an infection, causing swelling, stiffness, and pain.
The active ingredient in Actemra, tocilizumab, interferes with the chemicals that “signal” the immune system to mount an attack, so the result is a slowing down or suppression of the immune system.
Actemra is injected by a healthcare provider by IV infusion or by using a prefilled syringe. However, a pen injector is available for purchase as a prescription drug. Actemra is injected once per week or every other week, and may be used alone or in combination with other medication(s).
Actemra suppresses the immune system and sometimes lowers white blood cell counts, the first line of defense against infections. So Actemra lowers the body's ability to prevent or fight infections, putting patients at a higher risk of infections, including severe and life-threatening infections. Patients with active infections should not take Actemra unless approved by the prescribing physician. Immune suppression also increases the risk of certain types of cancer.
Other side effects include headache, dizziness, itching, stomach cramps, sore throat, runny or stuffy nose, sinus pain, liver problems, and perforations of the stomach or intestines. Allergic reactions are rare but can be severe. If you have signs of an allergic reaction, such as swelling of the lips, tongue, or face, and/or difficulty breathing, get emergency medical treatment.
This is not a complete list of possible side effects. Consult with your prescribing physician and pharmacist for medical advice about possible side effects before starting on Actemra.
Ask your doctor before using Actemra if you have liver problems. Do not get a live vaccine while taking Actemra.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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