What is Adcetris: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Adcetris overview

BRAND NAMES:

  • Adcetris

Generic Names:

  • Adcetris

Uses:

  • Treats cancer, including Hodgkin lymphoma, systemic anaplastic large cell lymphoma, peripheral T-cell lymphoma, and primary cutaneous anaplastic large cell lymphoma.

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Adcetris used for?

Adcetris is a cancer medication that works by interfering with the growth and spread of cancer cells in the body. It is used to treat adult patients with newly diagnosed Stage 3 or 4 classical Hodgkin lymphoma (cHL) in combination with chemotherapy.

What form(s) does Adcetris come in

  • Injectable

What are common Adcetris doses?

  • Solution Reconstituted 50MG

Common Adcetris prescriptions

  • Adcetris
    50mg solution reconstituted

How to take Adcetris

  • Missed dose: Injection routeCall your doctor or pharmacist for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will have to stay in place for at least 30 minutes.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • You may also receive other medicines (including fever medicine, allergy medicine, steroids, G-CSF) to help prevent possible allergic reactions to the injection.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • You may also receive other medicines (including fever medicine, allergy medicine, steroids, G-CSF) to help prevent possible allergic reactions to the injection.

  • Missed dose: Injection routeCall your doctor or pharmacist for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will have to stay in place for at least 30 minutes.

What to do if you miss a dose of Adcetris

Adcetris contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to brentuximab, or if you are pregnant.

Adcetris warnings

  • Injection routeThis medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Use an effective form of birth control during treatment with this medicine and for at least 6 months after your last dose. Male patients with female partners should use an effective form of birth control during treatment and for at least 6 months after the last dose.

  • Do not breastfeed during treatment with this medicine.

  • Tell your doctor if you have kidney disease, liver disease, diabetes, lung or breathing problems, or stomach or bowel problems.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • This medicine may cause the following problems: Peripheral neuropathy (nerve problem)Infusion reactionIncreased risk for serious infectionsTumor lysis syndrome (electrolyte and metabolic problem that can be life-threatening)Liver problemsProgressive multifocal leukoencephalopathy (brain infection that can be life-threatening)New or worsening lung problemsSerious skin reactionsStomach or bowel problems, including bleeding, blockage, perforation, or ulcersHigh blood sugar

  • Talk with your doctor before using this medicine if you plan to have children. Some men who use this medicine have become infertile (unable to have children).

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Severe stomach pain, bloody or black stools, vomiting of material that looks like coffee grounds

  • Unusual bleeding, bruising, or weakness

Adcetris interactions

  • Do not receive this medicine together with bleomycin.

  • Some medicines can affect how brentuximab works. Tell your doctor if you are using ketoconazole or rifampin.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • This medicine may cause the following problems: Peripheral neuropathy (a nerve problem)Infusion reactionLiver damageTumor lysis syndrome (electrolyte and metabolic problem that can be life-threatening)Progressive multifocal leukoencephalopathy (brain infection that can be life-threatening)New or worse lung problemsSerious skin reactionsStomach or bowel problems, including bleeding, blockage, perforation, or ulcers

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Adcetris side effects

Serious Side Effects

  • Difficult or painful urination, bloody or cloudy urine

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Unusual bleeding, bruising, or weakness

  • Fever of 100.5 degrees F or higher, chills, cough, sore throat, body aches

  • Severe stomach pain, bloody or black stools, vomiting of material that looks like coffee grounds

  • Trouble breathing, coughing up blood, headache

  • Confusion, changes in mood or behavior, problems with vision, speech, memory, or walking

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, or red skin rash

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Increased hunger or thirst, dry mouth, sweating

Less Serious Side Effects

  • Trouble sleeping

  • Constipation, diarrhea, mild stomach pain

  • Decreased weight

  • Tiredness

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