Dificid Coupons & Prices

Fidaxomicin

Dificid is a prescription antibiotic medication used to treat Clostridium difficile-associated diarrhea (CDAD), a severe intestinal condition caused by a resistant form of bacteria. It helps treat symptoms such as diarrhea, abdominal pain, and cramping. This medication works as a macrolide antibiotic that targets and kills Clostridium difficile bacteria in the intestines. For a standard supply of 20, 200mg tablets, the average retail price of Dificid is around $6,553.98. Use a SingleCare Dificid coupon and save on your total today by paying our lowest price of $1,788.11 per refill.

Set your location
Get alerted when the price
changes more than 10%

2 tablet200mgEdit

Unlock members-only prices.Free signup.

You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.

Dificid coupon at CVS Pharmacy
$1791.11
$ 1,788
$3 off with signupwith signup

Show this free card to your pharmacist.

Coupon card loading
Dificid coupon at Walgreens Pharmacy
$1905.53
$ 1,903
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Dificid coupon at Publix Pharmacy
$2922.01
$ 2,919
$3 off with signupwith signup
Dificid coupon at Kroger Pharmacy
$4454.18
$ 4,451
$3 off with signupwith signup
Dificid coupon at Harris Teeter Pharmacy
$4454.18
$ 4,451
$3 off with signupwith signup
Dificid coupon at Walmart Neighborhood Market Pharmacy
$4753.96
$ 4,751
$3 off with signupwith signup
$4753.96
$ 4,751
$3 off with signupwith signup
$ 4,755
$ 4,757

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/06/2025

Members save the most

Save big on your prescriptions
with the free SingleCare app.
4.8 average rating
About Dificid

Dificid is a prescription antibiotic medication used to treat Clostridium difficile-associated diarrhea (CDAD), a severe intestinal condition caused by a resistant form of bacteria. It helps treat symptoms such as diarrhea, abdominal pain, and cramping. This medication works as a macrolide antibiotic that targets and kills Clostridium difficile bacteria in the intestines. For a standard supply of 20, 200mg tablets, the average retail price of Dificid is around $6,553.98. Use a SingleCare Dificid coupon and save on your total today by paying our lowest price of $1,788.11 per refill.

Dificid Price History & Information

Price History for Dificid (Brand) & Fidaxomicin (Generic)

20 count, tablet, 200mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Dificid (Brand) & Fidaxomicin (Generic)

20 count, tablet, 200mg
PharmacyDificid Retail PriceFidaxomicin Retail PriceFidaxomicin SingleCare Price
CVS Pharmacy$6125.00$5054.00$1791.20
Walmart-$4265.00$4265.00
Walgreens$7334.40$4153.60$1911.20
Kroger Pharmacy$6246.00$5933.40$4454.20
Albertsons Pharmacy-$4922.60$4459.20

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Dificid

Dificid is a prescription antibiotic medication used to treat Clostridium difficile-associated diarrhea (CDAD), a severe intestinal condition caused by a resistant form of bacteria. It helps treat symptoms such as diarrhea, abdominal pain, and cramping. This medication works as a macrolide antibiotic that targets and kills Clostridium difficile bacteria in the intestines. For a standard supply of 20, 200mg tablets, the average retail price of Dificid is around $6,553.98. Use a SingleCare Dificid coupon and save on your total today by paying our lowest price of $1,788.11 per refill.

Dificid FAQs

How much does Dificid cost without insurance?

Without the necessary insurance coverage, you may end up paying as much as $6,553.98 for your Dificid prescription. To save on this cost, you could use a SingleCare Dificid coupon and pay a reduced cost of $1,788.11 for 20, 200mg tablets. These savings are redeemable at many local pharmacies, including Walmart, Kroger, Fry's, Harris Teeter, and Walgreens.

How much does Dificid cost with insurance?

The average cost of Dificid with insurance tends to vary based on the type of health insurance plan you're enrolled in and the level of benefits you're entitled to. You may need to contact your insurance provider directly to get an accurate cost for your Dificid prescription. You can also save money and pay a discounted price of $1,788.11 for 20, 200mg tablets by using SingleCare's Dificid drug coupons. Redeem instant savings at a participating pharmacy near you.

Does Medicare cover Dificid and how much does it cost?

Dificid is currently covered by many Medicare Part D and Medicare Advantage plans. Your average copay with Medicare coverage varies. Even with Medicare coverage, your prescription costs may still be too high.

Use SingleCare's savings cards to help lower your total Dificid cost. You may owe only $1,788.11 instead of $6,553.98 for 20, 200mg tablets of Dificid when you use SingleCare savings at participating drugstores like CVS, Kroger, and Walgreens.

Is there a generic of Dificid?

Dificid is a brand-name prescription drug. A generic alternative is currently unavailable for this medication.

What is Dificid?

Dificid is a prescription antibiotic medication used to treat Clostridium difficile-associated diarrhea (CDAD), a severe intestinal condition caused by a form of resistant bacteria. Dificid helps to reduce symptoms such as diarrhea and abdominal pain. The active ingredient in this medication is fidaxomicin. It works by targeting and eliminating a strain of bacteria called Clostridium difficile.

The Dificid antibiotic works within your intestines and is usually not absorbed by your body. This medication is only meant to treat infections caused by C. difficile. It will not be effective against viral infections, such as the common cold. Consult your doctor or pharmacist before using this medication. Not taking Dificid as instructed could lead to decreased effectiveness of the medication.

Dificid is a brand name medication that comes in the form of an oral tablet that can be taken with or without food. The usual dose is 200 mg taken twice daily for 10 days. Continue using this medication as prescribed by your health care professional until the treatment is complete. Do not end your treatment early, especially if you notice that your symptoms have disappeared. Stopping treatment early may cause the infection to return and increase the risk of antibiotic resistance.

What are the side effects of Dificid?

Common side effects that may result from the use of Dificid include vomiting, nausea, or abdominal pain. Inform your doctor if you experience these side effects or they persist or worsen.

Seek immediate medical attention if you experience serious side effects, such as black or bloody stool, vomit that resembles coffee grounds, unusual tiredness, or signs of an infection, such as chills and persistent sore throat. Allergic reactions to this medication are rare but should be reported immediately. Symptoms of an allergic or hypersensitivity reaction may include itching, rash, swelling, severe dizziness, and trouble breathing.

Other side effects not listed here may also occur as this is not a complete list. Consult your healthcare provider for medical advice on the risks and benefits of using Dificid.

Where are Dificid coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.