Dificid is a prescription antibiotic medication used to treat Clostridium difficile-associated diarrhea (CDAD), a severe intestinal condition caused by a resistant form of bacteria. It helps treat symptoms such as diarrhea, abdominal pain, and cramping. This medication works as a macrolide antibiotic that targets and kills Clostridium difficile bacteria in the intestines. For a standard supply of 20, 200mg tablets, the average retail price of Dificid is around $6,553.98. Use a SingleCare Dificid coupon and save on your total today by paying our lowest price of $1,788.11 per refill.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/06/2025
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Dificid is a prescription antibiotic medication used to treat Clostridium difficile-associated diarrhea (CDAD), a severe intestinal condition caused by a resistant form of bacteria. It helps treat symptoms such as diarrhea, abdominal pain, and cramping. This medication works as a macrolide antibiotic that targets and kills Clostridium difficile bacteria in the intestines. For a standard supply of 20, 200mg tablets, the average retail price of Dificid is around $6,553.98. Use a SingleCare Dificid coupon and save on your total today by paying our lowest price of $1,788.11 per refill.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Dificid Retail Price | Fidaxomicin Retail Price | Fidaxomicin SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $6125.00 | $5054.00 | $1791.20 |
| Walmart | - | $4265.00 | $4265.00 |
| Walgreens | $7334.40 | $4153.60 | $1911.20 |
| Kroger Pharmacy | $6246.00 | $5933.40 | $4454.20 |
| Albertsons Pharmacy | - | $4922.60 | $4459.20 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Dificid is a prescription antibiotic medication used to treat Clostridium difficile-associated diarrhea (CDAD), a severe intestinal condition caused by a resistant form of bacteria. It helps treat symptoms such as diarrhea, abdominal pain, and cramping. This medication works as a macrolide antibiotic that targets and kills Clostridium difficile bacteria in the intestines. For a standard supply of 20, 200mg tablets, the average retail price of Dificid is around $6,553.98. Use a SingleCare Dificid coupon and save on your total today by paying our lowest price of $1,788.11 per refill.
Without the necessary insurance coverage, you may end up paying as much as $6,553.98 for your Dificid prescription. To save on this cost, you could use a SingleCare Dificid coupon and pay a reduced cost of $1,788.11 for 20, 200mg tablets. These savings are redeemable at many local pharmacies, including Walmart, Kroger, Fry's, Harris Teeter, and Walgreens.
The average cost of Dificid with insurance tends to vary based on the type of health insurance plan you're enrolled in and the level of benefits you're entitled to. You may need to contact your insurance provider directly to get an accurate cost for your Dificid prescription. You can also save money and pay a discounted price of $1,788.11 for 20, 200mg tablets by using SingleCare's Dificid drug coupons. Redeem instant savings at a participating pharmacy near you.
Dificid is currently covered by many Medicare Part D and Medicare Advantage plans. Your average copay with Medicare coverage varies. Even with Medicare coverage, your prescription costs may still be too high.
Use SingleCare's savings cards to help lower your total Dificid cost. You may owe only $1,788.11 instead of $6,553.98 for 20, 200mg tablets of Dificid when you use SingleCare savings at participating drugstores like CVS, Kroger, and Walgreens.
Dificid is a brand-name prescription drug. A generic alternative is currently unavailable for this medication.
Dificid is a prescription antibiotic medication used to treat Clostridium difficile-associated diarrhea (CDAD), a severe intestinal condition caused by a form of resistant bacteria. Dificid helps to reduce symptoms such as diarrhea and abdominal pain. The active ingredient in this medication is fidaxomicin. It works by targeting and eliminating a strain of bacteria called Clostridium difficile.
The Dificid antibiotic works within your intestines and is usually not absorbed by your body. This medication is only meant to treat infections caused by C. difficile. It will not be effective against viral infections, such as the common cold. Consult your doctor or pharmacist before using this medication. Not taking Dificid as instructed could lead to decreased effectiveness of the medication.
Dificid is a brand name medication that comes in the form of an oral tablet that can be taken with or without food. The usual dose is 200 mg taken twice daily for 10 days. Continue using this medication as prescribed by your health care professional until the treatment is complete. Do not end your treatment early, especially if you notice that your symptoms have disappeared. Stopping treatment early may cause the infection to return and increase the risk of antibiotic resistance.
Common side effects that may result from the use of Dificid include vomiting, nausea, or abdominal pain. Inform your doctor if you experience these side effects or they persist or worsen.
Seek immediate medical attention if you experience serious side effects, such as black or bloody stool, vomit that resembles coffee grounds, unusual tiredness, or signs of an infection, such as chills and persistent sore throat. Allergic reactions to this medication are rare but should be reported immediately. Symptoms of an allergic or hypersensitivity reaction may include itching, rash, swelling, severe dizziness, and trouble breathing.
Other side effects not listed here may also occur as this is not a complete list. Consult your healthcare provider for medical advice on the risks and benefits of using Dificid.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved