What is Allegra-D Allergy & Congestion: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Allegra-D Allergy & Congestion overview

BRAND NAMES:

  • Allegra-D, Allegra-D 12 Hour, Allegra-D 12 Hour Allergy & Congestion, Allegra-D 24 Hour Allergy & Congestion, Allegra-D 24HR, Allergy Relief-D, Antihistamine & Nasal Decongestant, Leader 12HR Allergy and Congestion, Wal-Fex D

Generic Names:

  • Fexofenadine-Pseudoephed Er

Uses:

  • Treats allergy (hay fever) symptoms such as sneezing, runny or stuffy nose, itchy throat, and itchy or watery eyes. This medicine is a combination of an antihistamine and a decongestant.

Therapeutic Classes:

  • Antihistamine, Less-Sedating/Decongestant Combination, Antihistamine/Decongestant Combination

Forms:

  • Long Acting Tablet, 24 Hour Tablet

How it’s taken:

  • By mouth

What is Allegra-D Allergy & Congestion used for?

What form(s) does Allegra-D Allergy & Congestion come in

  • Long Acting Tablet

  • 24 Hour Tablet

What are common Allegra-D Allergy & Congestion doses?

  • Box 10 Tablets Extended Release 24 Hour

  • Box 10 Tablets Extended Release 12 Hour

  • Box 15 Tablets Extended Release 24 Hour

  • Box 20 Tablets Extended Release 12 Hour

  • Box 30 Tablets Extended Release 12 Hour

Common Allegra-D Allergy & Congestion prescriptions

  • Allegra-D Allergy & Congestion
    10 tablets extended release 12 hour bottle

  • Allegra-D Allergy & Congestion
    20 tablets extended release 12 hour bottle

  • Allegra-D Allergy & Congestion
    10 tablets extended release 12 hour box

  • Allegra-D Allergy & Congestion
    10 tablets extended release 24 hour box

  • Allegra-D Allergy & Congestion
    15 tablets extended release 24 hour box

  • Allegra-D Allergy & Congestion
    20 tablets extended release 12 hour box

  • Allegra-D Allergy & Congestion
    30 tablets extended release 12 hour box

  • Allegra-D Allergy & Congestion
    5 tablets extended release 24 hour box

How to take Allegra-D Allergy & Congestion

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Swallow the tablet whole. Do not crush, chew, or break the tablet.

  • Oral routeIt is best to take this medicine on an empty stomach.

  • This medicine is not for children under 12 years of age.

  • This medicine is not for children under 12 years of age.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Oral routeIt is best to take this medicine on an empty stomach.

  • Swallow the tablet whole. Do not crush, chew, or break the tablet.

What to do if you miss a dose of Allegra-D Allergy & Congestion

  • If you miss a dose or forget to use your medicine, use it as soon as you can. Then wait at least 12 hours before taking your next dose. Do not use two doses at the same time.

  • Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allegra-D Allergy & Congestion contraindications

  • You should not use this medicine if you have had an allergic reaction to fexofenadine or pseudoephedrine. Tell your doctor if you have ever had an allergic reaction to any drug. You should not use this medicine if you have narrow-angle glaucoma, severe hypertension, or severe heart disease, or if you are unable to urinate. You should not use this medicine if you have used an MAO inhibitor such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days.

Allegra-D Allergy & Congestion warnings

  • Make sure your doctor knows if you are pregnant or breast feeding.

  • Tell your doctor if you have diabetes, glaucoma, heart disease, high blood pressure, or an overactive thyroid. Make sure your doctor knows if you have kidney disease, or trouble urinating due to an enlarged prostate.

  • Decrease in how much or how often you urinate.

  • Fast, irregular, or pounding heartbeat.

  • Hallucinations.

  • Lightheadedness, fainting, or convulsions (seizures).

  • Problems with urination.

  • Severe weakness, dizziness, tremors, or trouble sleeping.

Allegra-D Allergy & Congestion interactions

  • Avoid drinking fruit juices such as apple juice, orange juice, and grapefruit juice while you are using this medicine.

  • Make sure your doctor knows about all other medicines you are using, especially erythromycin (E-Mycin®, E.E.S.®), digoxin (Lanoxin®), ketoconazole (Nizoral®), or medicine for high blood pressure.

  • Tell your doctor if you are using an antacid such as Maalox®. Certain antacids should not be taken together with fexofenadine/pseudoephedrine. Ask your doctor about how much time to allow between taking this medicine and taking an antacid.

  • Do not use any other allergy or cold medicines with fexofenadine/pseudoephedrine unless your doctor tells you to.

Allegra-D Allergy & Congestion side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Cough, sneezing, sore throat, chest congestion.

  • Decrease in how much or how often you urinate.

  • Fast, irregular, or pounding heartbeat.

  • Hallucinations.

  • Lightheadedness, fainting, or convulsions (seizures).

  • Severe weakness, dizziness, tremors, or trouble sleeping.

  • Problems with urination.

Less Serious Side Effects

  • Dry mouth, irritated throat.

  • Sweating or increased thirst.

  • Headache, drowsiness.

  • Feeling restless, anxious, fearful, or excited.

  • Nausea or upset stomach.

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