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Lidocaine-Prilocaine
Relieves pain. Also numbs the skin or genital area before certain medical procedures. This medicine is a topical anesthetic.
Anesthetic, Local, Anesthetic Combination
Cream, Thin Sheet
On the skin
Lidocaine-Prilocaine is prescribed to adults to numb an area of the body before an operation. This anesthetic is often applied to the penis and vagina before surgery to ensure that the patient doesn’t feel pain during the operation.
Cream
Thin Sheet
Box 1 Kit
Anodyne LPT
1 kit box
A nurse or other trained health professional will give you this medicine. The medicine is usually applied right before the medical procedure in a hospital or clinic.
You may be taught how to apply this medicine to yourself or your child at home before the medical procedure.
Your doctor will tell you how much medicine to use. Do not use more than directed. Do not use it for any other condition without first checking with your doctor. This medicine may cause unwanted effects if too much is used, because more of it is absorbed through the skin.
Do not get this medicine near or into your eyes. If it does get into your eyes, rinse with water or saline solution right away.
Do not apply this medicine to open wounds, burns, broken, or inflamed skin, or to a large area of skin unless directed by your doctor.
Topical application routeWash your hands with soap and water before and after you use this medicine.
Apply a thick layer of medicine to the area where numbness is needed. Do not spread the medicine on the skin.
Cover the medicine with a special bandage called an occlusive dressing. This will keep the medicine in place. Your doctor will give you the bandage or tell you what to use.
Seal the edges of the bandage to keep the medicine from leaking. Do not lift the bandage or disturb it. Keeping the medicine tightly covered helps it work properly.
For babies or young children, a second covering may be used to prevent them from touching the medicine.
Carefully watch your baby or child while the medicine is in place. Do not let them loosen or remove the bandage, touch the medicine, or put it in the mouth, eyes, nose, or ears.
Keep the bandage in place until you or your child arrive at the hospital or clinic.
Your doctor will remove the bandage and wipe the medicine off the skin before the medical procedure.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Topical application route: Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Topical application route: Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
This medicine is not right for everyone. Do not use it if you had an allergic reaction to lidocaine, prilocaine, or similar medicines.
Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, kidney disease, heart disease, heart rhythm problems, a blood disorder, G6PD, or lung or breathing problems.
This medicine may cause a rare, but serious blood problem called methemoglobinemia.
During the time that the skin feels numb, serious injury can occur. Be especially careful to avoid injury until the numbness wears off and you or your child have normal feeling in the area. Do not scratch or rub the area, and do not allow very hot or very cold objects to touch it.
Topical application route: Do not use this medicine to treat a skin problem your doctor has not examined.
Call your doctor if your symptoms do not improve or if they get worse.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Some medicines can affect how lidocaine/prilocaine works. Tell your doctor if you are using any of the following: Acetaminophen, chloroquine, metoclopramide, mexiletine, primaquine, quinine, sulfasalazine, tocainideCancer medicine (including cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase)Medicine for heart rhythm problems (including amiodarone, bretylium, dofetilide, sotalol)Medicine to treat an infection (including dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamide)Medicine to treat seizures (including phenobarbital, phenytoin, sodium valproate)Nitrate or nitrite medicine (including nitric oxide, nitroglycerin, nitroprusside, nitrous oxide)
Tell your doctor if you are also using a medicine to treat an abnormal heart rhythm such as amiodarone (Cordarone®), bretylium (Bretylol®), dofetilide (Tikosyn®), flecainide (Tambocor®), mexiletine (Mexitil®), propafenone (Rythmol®), quinidine (Cardioquin®, Quinaglute®, Quinidex®), sotalol (Betapace®), or tocainide (Tonocard®).
Topical application route: Do not use this medicine to treat a skin problem your doctor has not examined.
During the time that the skin feels numb, serious injury can occur. Be especially careful to avoid injury until the numbness wears off and you or your child have normal feeling in the area. Do not scratch or rub the area, and do not allow very hot or very cold objects to touch it.
Using too much of this medicine or using it on a large area of your skin can cause serious unwanted effects. Remove the cream and contact your doctor right away if you or your child have any of these symptoms: lightheadedness, dizziness, vision problems, an irregular or slow heartbeat, difficulty with breathing, or convulsions.
This medicine may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have a rash; itching; hoarseness; trouble with breathing; trouble with swallowing; or any swelling of the hands, face, or mouth after you receive the medicine.
This medicine may cause a rare, but serious blood problem called methemoglobinemia. Remove the cream and call your doctor right away if you or your child develop a blue or bluish purple color on the lips, fingernails, or skin, or have headaches, dizziness, fainting, sleepiness, or trouble with breathing.
Serious Side Effects
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Confusion, dizziness, sleepiness, lightheadedness
Hearing loss, ringing or buzzing in the ears (when applied into the middle ear)
Pale, gray, or blue lips, nails, or skin, dark urine, headache, unusual tiredness or weakness, fast heartbeat
Tremors or seizures
Troubled or shallow breathing
Less Serious Side Effects
Redness, itching, burning, or swelling where the patch is applied
Pale or red skin where the medicine was applied.
Swelling of the skin where the medicine was applied.
Health education, drug info, wellness & more
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Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved