Lubiprostone Coupons & Prices

Amitiza

Lubiprostone is a Gastrointestinal Chloride Channel Activators class drug that is manufactured by Par Health Usa. The typical counter price of Lubiprostone is $446.02 per 60, 24mcg capsules, but you can pay only $40.56 for 60, 24mcg capsules with your SingleCare card. Lubiprostone is a generic prescription; Amitiza is the brand variant of Lubiprostone.

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Lubiprostone coupon at CVS Pharmacy
$43.56
$ 40.56
$3 off with signupwith signup

Show this free card to your pharmacist.

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Lubiprostone coupon at Costco Pharmacy
$ 66.99

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Lubiprostone coupon at Food Lion Pharmacy
$ 68.31
Lubiprostone coupon at Publix Pharmacy
$ 75.29
Lubiprostone coupon at Walgreens Pharmacy
$79.86
$ 76.86
$3 off with signupwith signup
Lubiprostone coupon at Walmart Neighborhood Market Pharmacy
$110.45
$ 107.45
$3 off with signupwith signup
$110.45
$ 107.45
$3 off with signupwith signup
$128.76
$ 125.76
$3 off with signupwith signup
$128.76
$ 125.76
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Lubiprostone

Lubiprostone is a Gastrointestinal Chloride Channel Activators class drug that is manufactured by Par Health Usa. The typical counter price of Lubiprostone is $446.02 per 60, 24mcg capsules, but you can pay only $40.56 for 60, 24mcg capsules with your SingleCare card. Lubiprostone is a generic prescription; Amitiza is the brand variant of Lubiprostone.

Lubiprostone Price History & Information

Price History for Lubiprostone (Generic) & Amitiza (Brand)

60 count, capsule, 24mcg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Lubiprostone (Generic) & Amitiza (Brand)

60 count, capsule, 24mcg
PharmacyAmitiza Retail PriceLubiprostone Retail PriceLubiprostone SingleCare Price
CVS Pharmacy-$309.00$98.40
Walmart-$400.80$110.40
Walgreens-$163.80$130.20
Kroger Pharmacy$485.40$404.76$129.00
Albertsons Pharmacy-$384.00$209.40

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Lubiprostone

Lubiprostone is a Gastrointestinal Chloride Channel Activators class drug that is manufactured by Par Health Usa. The typical counter price of Lubiprostone is $446.02 per 60, 24mcg capsules, but you can pay only $40.56 for 60, 24mcg capsules with your SingleCare card. Lubiprostone is a generic prescription; Amitiza is the brand variant of Lubiprostone.

Lubiprostone FAQs

How much is Lubiprostone with SingleCare?

Lubiprostone costs $40.56 for 60, 24mcg capsules with a free Lubiprostone coupon from SingleCare.  But, you could reduce this cost more depending on your Rx information. Use the dropdown menu above to update your prescription details (i.e., brand/generic, form, dosage, quantity) to see the most accurate prices of Lubiprostone with SingleCare at your local pharmacies.

How much does Lubiprostone cost without insurance?

The average cash price of Lubiprostone without health insurance is $446.02 per 60, 24mcg capsules though you can save money using a SingleCare Lubiprostone coupon to pay just $40.56 for 60, 24mcg capsules of Lubiprostone. If you don’t have insurance can always use SingleCare for free Lubiprostone coupons. By using Lubiprostone, you typically reduce your price on your medication opposed to using Amitiza - the branded form of Lubiprostone, which usually costs much more than Lubiprostone. 

How much does Lubiprostone cost with insurance?

Every individual insurance drug plan is different and may or may not cover Lubiprostone. The cost of Lubiprostone with insurance coverage differs according to your plan - reach out to your insurance provider for particular formulary coverage and payment guidance. If your insurance does not include Lubiprostone, you can use SingleCare to get a better rate on Lubiprostone at your local pharmacies. Also, you can also use SingleCare cards if you have Medicare or Medicaid. In the event that Medicare or Medicaid doesn’t offer your Lubiprostone order, you can use SingleCare instead. Visit the SingleCare website or app to compare the lowest price of Lubiprostone with SingleCare versus your Lubiprostone price with insurance or Medicare.

How to use SingleCare for Lubiprostone

SingleCare is accepted at most major pharmacies and grocery stores, i.e., Walgreens, Kroger, Walmart, CVS, Safeway, and more. Simply text, email, print, or save your free Lubiprostone coupon to your mobile wallet and show your pharmacist when you pick up your prescription.

What is the brand name of Lubiprostone?

Lubiprostone is the generic version of Amitiza and is significantly cheaper than Amitiza. The SingleCare price for Lubiprostone is $40.56 per 60, 24mcg capsules, which usually is dramatically less expensive than the typical cost for Amitiza but has the same active ingredients.

Where are Lubiprostone coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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