Lubiprostone Coupons & Prices

Amitiza

Lubiprostone is a Gastrointestinal Chloride Channel Activators class drug that is manufactured by Par Health Usa. The typical counter price of Lubiprostone is $440.17 per 60, 24mcg capsules, but you can pay $38.95 for 60, 24mcg capsules with the SingleCare coupon. Lubiprostone is a generic drug; Amitiza is the branded version of Lubiprostone.

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Lubiprostone coupon at CVS Pharmacy
$41.95
$ 38.95
$3 off with signupwith signup

Show this free card to your pharmacist.

This coupon is not insurance.
Lubiprostone coupon at Publix Pharmacy
$ 59.86
Lubiprostone coupon at Costco Pharmacy
$ 66.99
Lubiprostone coupon at Food Lion Pharmacy
$ 68.31
Lubiprostone coupon at Walgreens Pharmacy
$79.75
$ 76.75
$3 off with signupwith signup
Lubiprostone coupon at Walmart Neighborhood Market Pharmacy
$110.45
$ 107.45
$3 off with signupwith signup
$110.45
$ 107.45
$3 off with signupwith signup
$128.76
$ 125.76
$3 off with signupwith signup
$128.76
$ 125.76
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 03/20/2026

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About Lubiprostone

Lubiprostone is a Gastrointestinal Chloride Channel Activators class drug that is manufactured by Par Health Usa. The typical counter price of Lubiprostone is $440.17 per 60, 24mcg capsules, but you can pay $38.95 for 60, 24mcg capsules with the SingleCare coupon. Lubiprostone is a generic drug; Amitiza is the branded version of Lubiprostone.

Lubiprostone Price History & Information

Price History for Lubiprostone (Generic) & Amitiza (Brand)

60 count, capsule, 24mcg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Lubiprostone (Generic) & Amitiza (Brand)

60 count, capsule, 24mcg
PharmacyAmitiza Retail PriceLubiprostone Retail PriceLubiprostone SingleCare Price
CVS Pharmacy-$309.00$40.30
Walmart-$218.28$102.18
Walgreens$481.80$130.20$121.52
Kroger Pharmacy-$406.35$129.00
Albertsons Pharmacy$540.60$387.60$209.40

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Lubiprostone

Lubiprostone is a Gastrointestinal Chloride Channel Activators class drug that is manufactured by Par Health Usa. The typical counter price of Lubiprostone is $440.17 per 60, 24mcg capsules, but you can pay $38.95 for 60, 24mcg capsules with the SingleCare coupon. Lubiprostone is a generic drug; Amitiza is the branded version of Lubiprostone.

Lubiprostone FAQs

How much is Lubiprostone with SingleCare?

Lubiprostone costs $38.95 for 60, 24mcg capsules with a free Lubiprostone coupon from SingleCare.  But, you could reduce this cost more depending on your Rx information. Use the dropdown menu above to update your prescription details (i.e., brand/generic, form, dosage, quantity) to see the most accurate prices of Lubiprostone with SingleCare at your local pharmacies.

How much does Lubiprostone cost without insurance?

The average cash price of Lubiprostone without health insurance is $440.17 per 60, 24mcg capsules though you can save money using a SingleCare Lubiprostone coupon to pay $38.95 for 60, 24mcg capsules of Lubiprostone. If you don’t have access to insurance coverage can still use SingleCare for free Lubiprostone coupons. By getting Lubiprostone, you generally save on your medication instead of buying Amitiza - the branded form of Lubiprostone, which often costs much more than Lubiprostone. 

How much does Lubiprostone cost with insurance?

Each specific insurance plan is distinct and may or may not cover Lubiprostone. The cost of Lubiprostone with insurance coverage varies depending on your plan - contact your insurance provider for definitive formulary coverage and payment guidance. If your insurance does not cover Lubiprostone, you can use a SingleCare card to save on Lubiprostone at participating pharmacies. In addition, you can also use SingleCare discounts if you have Medicare or Medicaid. When Medicare or Medicaid doesn’t offer your Lubiprostone order, try SingleCare instead. Use the SingleCare website or app to review the lowest cost of Lubiprostone with SingleCare versus your Lubiprostone copay with insurance or Medicare.

How to use SingleCare for Lubiprostone

You can use SingleCare coupons at most major pharmacies and grocery stores, i.e., Walgreens, Kroger, Walmart, CVS, Safeway, and more. Text, email, print, or save your free Lubiprostone coupon to your mobile wallet and show your pharmacist at the counter.

What is the brand name of Lubiprostone?

Lubiprostone is the generic version of Amitiza and is significantly cheaper than Amitiza. The SingleCare price of Lubiprostone is $38.95 per 60, 24mcg capsules, which typically is much cheaper than the cost for Amitiza but has the same ingredients.

Where are Lubiprostone coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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