Anucort HC is a prescription suppository that treats hemorrhoids and other inflammatory conditions of the anus and rectum. Its active ingredient is hydrocortisone, a topical corticosteroid that reduces swelling. Anucort HC is used two or three times a day for short periods (two to six weeks).
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Anucort-HC
Hydrocortisone acetate
Treats inflammation of the rectum and anus due to hemorrhoids, proctitis, ulcerative colitis, and similar inflammatory conditions
Topical corticosteroid, anti-inflammatory, anti-hemorrhoidal agent
Suppository
Into the rectum
Anucort-HC is used to treat inflamed hemorrhoids and radiation-induced proctitis. It is also used along with other drugs for ulcerative colitis, cryptitis, and other inflammatory conditions involving the rectum or anus.
Suppository
25 mg
For inflammatory conditions of the rectum or anus: 25 mg (one suppository) inserted into the rectum twice daily for two weeks
For more severe inflammatory conditions of the rectum or anus: 25 mg (one suppository) inserted into the rectum three times daily for six to eight weeks
Anucort-HC
12 suppository box
Anucort-HC
24 suppository box
Follow all the prescriber’s instructions.
Doses are inserted either twice daily or three times daily.
For twice daily dosing, insert a suppository once in the morning and once at night.
Detach one suppository from the strip.
To remove the suppository, hold it with the pointed end up.
Separate the tabs at the top and pull downwards for almost the full length of the suppository.
Gently remove the suppository. Only handle the suppository when you’re ready to insert it because it can easily melt.
Insert the pointed end into the anus and gently push the suppository into the rectum.
Store the suppositories in their foil wrap at room temperature.
Keep this medicine away from heat.
Do not freeze.
Ask the prescriber how to manage a missed dose.
Do not insert two suppositories to make up for a missed dose.
This medicine is not right for everyone.
Do not use it if you have had an allergic reaction to hydrocortisone.
Tell any doctor or other healthcare provider who treats you that you are using this medicine.
Keep all appointments with the prescriber.
Tell the prescriber if you are pregnant, breastfeeding, or have an active infection.
Anucort treatment may need to stop if an infection cannot be controlled by medications.
Anucort HC should only be used if a healthcare professional has performed a proctological examination.
Anucort HC may increase the risk of infections. If you experience symptoms of an infection, talk to your prescriber or other healthcare provider.
Anucort HC rarely causes serious side effects other than allergic reactions.
Contact the prescriber if any less serious side effect worsens or doesn’t go away.
Anucort HC may stain fabrics. Take necessary precautions.
Tell the prescriber about any drug that’s being taken, particularly other rectal medications or products.
As a topical medication, Anucort HC minimally interacts with other medications.
The Anucort HC prescribing information does not have any warnings or precautions about possible drug interactions.
Talk to a doctor if you notice any signs or symptoms of a possible serious side effect, including:
Rectal bleeding
Blood in the stools
Changes in mood or behavior
Heart rhythm abnormalities
Weakness, tiredness, nausea, vomiting, weight loss
Eye pain, vision changes
Infection: Sore throat, fever, painful urination, persistent anal irritation or redness
Allergic reaction: rash, itching, swelling of the face, tongue, or throat, trouble breathing
Rectal irritation, burning, or itching
Rectal or anal dryness
Folliculitis
Skin color changes
Anucort-HC, Kaiser Permanente
Anucort HC hydrocortisone acetate suppository prescribing information, DailyMed (NIH National Library of Medicine)
Hemorrhoidal HC drug summary, Prescriber’s Digital Reference (PDR)
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Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved