Dotti is a prescription estrogen (estradiol) patch FDA-approved to relieve moderate to severe menopausal symptoms (like hot flashes), prevent postmenopausal osteoporosis, and treat low estrogen. The retail Dotti price averages $187.92 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box. With a free coupon for Dotti from SingleCare, purchase generic Dotti for as little as $51.57 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 08/03/2026
Dotti is a prescription estrogen (estradiol) patch FDA-approved to relieve moderate to severe menopausal symptoms (like hot flashes), prevent postmenopausal osteoporosis, and treat low estrogen. The retail Dotti price averages $187.92 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box. With a free coupon for Dotti from SingleCare, purchase generic Dotti for as little as $51.57 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Dotti Retail Price | Estradiol Retail Price | Estradiol SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $142.00 | $119.30 | $48.82 |
| Walmart | $65.84 | $83.90 | $65.99 |
| Walgreens | $144.96 | $56.02 | $38.13 |
| Kroger Pharmacy | $144.00 | $135.73 | $75.60 |
| Albertsons Pharmacy | $69.12 | $126.14 | $59.00 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Dotti is a prescription estrogen (estradiol) patch FDA-approved to relieve moderate to severe menopausal symptoms (like hot flashes), prevent postmenopausal osteoporosis, and treat low estrogen. The retail Dotti price averages $187.92 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box. With a free coupon for Dotti from SingleCare, purchase generic Dotti for as little as $51.57 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box.
Dotti costs $51.57 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box with a free Dotti coupon from SingleCare. However, you could lower this cost more depending on your Rx information. Use the dropdown menu above to enter your prescription information (i.e., form, dosage, quantity|quantity, dosage, form|quantity, form, dosage]) to find the most accurate price of Dotti with SingleCare at a pharmacy near you.
Purchasing Dotti without insurance will typically cost $187.92 per 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box. Purchasing the generic version of Dotti through SingleCare’s discount program can save money. SingleCare’s best price for generic Dotti is $51.57 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box.
Dotti is typically covered by health insurance, but coverage may vary. However, nearly all health insurance plans cover generic Dotti. If approval or cost is a problem, use a SingleCare Dotti coupon without insurance and pay only $51.57 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box.
Medicare Part D usually covers Dotti, but not always. Insurance providers that don’t cover Dotti almost certainly cover generic Dotti. Most Medicare drug plans impose quantity limits on Dotti. They also place Dotti and generic Dotti in their higher-cost copay tiers, so the out-of-pocket cost may be more than expected. If cost or coverage is a problem, use a SingleCare Dotti coupon instead of Medicare. The SingleCare cost may be lower.
Medicaid does not commonly cover Dotti, but some states do and they’re more likely to cover generic versions. Approval may require prior authorization. If Medicaid denies a Dotti prescription, use a SingleCare discount card at a participating pharmacy to purchase Dotti for a cash price as low as $51.57 for 1, 1 box (8 twice weekly patches), 0.05mg/24 hr box.
Generic estradiol patches are a lower-priced alternative to Dotti and can be purchased at a discount with a SingleCare drug coupon. They work similarly and are available in the same dosage strengths (0.025 mg/day, 0.0375 mg/day, 0.05 mg/day, 0.075 mg/day, and 0.1 mg/day).
SingleCare offers free coupons for Dotti and other estrogen patches. Sign up for SingleCare for free to get our lowest prices on Dotti and earn bonus savings on refills when you use SingleCare.
Another way to save money is to switch to generic estradiol patches. If these are still too expensive, switching to oral estradiol pills is the most cost-effective option, particularly with a SingleCare coupon. Always consult a healthcare professional for medical advice first.
Community clinics, 340B providers, Medicare Extra Help, or Medicaid can also help cover the cost of Dotti. However, some women may not meet the eligibility requirements for these programs.
Finally, compare prices at local pharmacies. Search for your medication on SingleCare’s website or app and enter your zip code to find the pharmacies with the lowest Dotti prices near you.
Generic estradiol patches are the cheapest way to get something very similar to Dotti, but they aren’t the lowest-priced way to get estradiol hormone replacement therapy. That would be generic estradiol pills or generic estradiol topical gels. These options have their own unique problems, including effectiveness, side effects, and safety concerns such as an increased risk of blood clots when using pills. A healthcare professional can give medical advice about the pros and cons of switching to a different type of estradiol treatment.
SingleCare coupons are accepted at most major pharmacies and grocery stores, such as Walgreens, Kroger, Walmart, CVS, Safeway, and more. Simply text, email, print, or save your free Dotti coupon to your mobile wallet and show your pharmacist at checkout.
Jeff Fortner, Pharm.D., focuses his practice and research on pharmaceutical compounding, patient-centered care in the community setting, and pharmacist-provided clinical services. He maintains a practice site at an independent community pharmacy that also specializes in non-sterile compounding and long-term care medication preparation. Dr. Fortner enjoys spending time with his wife and two young daughters, trying and sharing new craft beers, reading sci-fi/fantasy fiction, and cycling.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved