Atovaquone-Proguanil tablets are FDA-approved to treat or prevent malaria. Without insurance, the retail price of Atovaquone-Proguanil averages $244.85 per 30, 250-100mg tablets. A free coupon from SingleCare can lower the Atovaquone-Proguanil price to $45.64 for 30, 250-100mg tablets at certain participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 03/20/2026
Atovaquone-Proguanil tablets are FDA-approved to treat or prevent malaria. Without insurance, the retail price of Atovaquone-Proguanil averages $244.85 per 30, 250-100mg tablets. A free coupon from SingleCare can lower the Atovaquone-Proguanil price to $45.64 for 30, 250-100mg tablets at certain participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Atovaquone-Proguanil Hcl Retail Price | Atovaquone-Proguanil Hcl SingleCare Price |
|---|---|---|
| CVS Pharmacy | $189.00 | $54.41 |
| Walmart | $102.30 | $59.10 |
| Walgreens | $119.70 | $78.30 |
| Kroger Pharmacy | $214.50 | $79.20 |
| Albertsons Pharmacy | $182.70 | $92.70 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Atovaquone-Proguanil tablets are FDA-approved to treat or prevent malaria. Without insurance, the retail price of Atovaquone-Proguanil averages $244.85 per 30, 250-100mg tablets. A free coupon from SingleCare can lower the Atovaquone-Proguanil price to $45.64 for 30, 250-100mg tablets at certain participating pharmacies.
The generic version of Atovaquone-Proguanil costs $45.64 for 30, 250-100mg tablets with a free Atovaquone-Proguanil coupon from SingleCare. However, you could pay even less depending on your prescription details. Use the dropdown menu above to update your prescription details (i.e., generic/brand, quantity, dosage, form) to get the most accurate prices of Atovaquone-Proguanil with SingleCare near you.
The cash price of Atovaquone-Proguanil averages $244.85 per 30, 250-100mg tablets. A SingleCare savings card can significantly reduce that price. Our lowest price for Atovaquone-Proguanil is $45.64 for 30, 250-100mg tablets.
Atovaquone-Proguanil is almost always covered by health insurance without restrictions. The out-of-pocket cost should be modest. Insurance providers typically place Atovaquone-Proguanil in the lowest copay tiers, but other fees may apply. If cost or coverage is an issue, use a SingleCare Atovaquone-Proguanil coupon without insurance and buy Atovaquone-Proguanil for as little as $45.64 for 30, 250-100mg tablets.
Atovaquone-Proguanil is nearly always covered by Medicare drug plans, but may have restrictions. The out-of-pocket cost may be higher than expected because many plans place Atovaquone-Proguanil in their highest copay tiers. Other fees, such as deductibles or coinsurance, will add to the out-of-pocket cost. If the cost with Medicare is a surprise, ask the pharmacist to compare the out-of-pocket cost with Medicare to the cost using a SingleCare Atovaquone-Proguanil coupon. The SingleCare price may be lower.
Many people with Medicaid are covered for Atovaquone-Proguanil, but some states do not cover it. Talk to the pharmacist when filing the prescription. If coverage is denied, use a SingleCare discount coupon instead of Medicaid. SingleCare’s lowest price for Atovaquone-Proguanil is $45.64 for 30, 250-100mg tablets at certain pharmacies.
Malarone is the brand-name version of Atovaquone-Proguanil. The average retail price of Malarone is a few dollars higher than that of Atovaquone-Proguanil. With a SingleCare discount card, the price of Atovaquone-Proguanil can be as low as $45.64 for 30, 250-100mg tablets.
The most certain and immediate way to save money is to purchase Atovaquone-Proguanil using SingleCare’s savings program. In addition to coupon savings, routinely using SingleCare coupons can earn extra savings for people who enroll in SingleCare’s loyalty program.
Other ways to save money include:
Comparing pharmacy prices for Atovaquone-Proguanil
Applying to a nonprofit patient assistance program or a local 340B provider
Enrolling in Medicaid or Medicare Part D Extra Help
The cheapest alternatives to Atovaquone-Proguanil treatment are mefloquine, chloroquine, and Coaratem (artemether-lumefantrine). All these alternatives can be used to treat a P. falciparum malaria infection.
Only Atovaquone-Proguanil, mefloquine, and chloroquine can be used to prevent a P. falciparum infection in people traveling to malaria-endemic areas. Doxycycline, a commonly prescribed antibiotic, is another lower-priced FDA-approved drug for preventing P. falciparum malaria in short-term travelers. It is not fast-acting enough to treat malaria without a drug like chloroquine. This combination is still cheaper than Atovaquone-Proguanil, but not by much.
There are cheaper antimalarial drugs than these examples, like primaquine, but they are not effective against the same parasite as Atovaquone-Proguanil. Other alternative P. falciparum drugs cost more than Atovaquone-Proguanil. Keep in mind that healthcare providers prescribe antimalarial drugs based on the type of organism, possible drug resistance, and underlying health conditions. If paying for antimalarial treatment is challenging, ask the clinician for medical advice about cheaper alternatives and the possible trade-offs.
You can use SingleCare coupons at most major pharmacies and grocery stores, such as Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Atovaquone-Proguanil coupon to your digital wallet and show a pharmacist at the counter.
SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2026 SingleCare Administrators. All rights reserved
© 2026 SingleCare Administrators. All rights reserved