What is Aztreonam: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Aztreonam overview

BRAND NAMES:

  • Azactam, Aztreonam Novaplus, PremierPro Rx aztreonam

Generic Names:

  • Aztreonam

Uses:

  • Treats infections caused by bacteria. This medicine is an antibiotic.

Therapeutic Classes:

  • Antibiotic

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Aztreonam used for?

Aztreonam is a prescription drug used to treat certain bacterial infections of the blood, urinary tract, stomach, skin, or lower respiratory tract. It may also be used to treat after infections caused by bacteria as prescribed by your doctor. Aztreonam works to stop the bacteria in the infected area from growing and spreading.

What form(s) does Aztreonam come in

  • Injectable

What are common Aztreonam doses?

  • Solution Reconstituted 1GM

  • Solution Reconstituted 2GM

Common Aztreonam prescriptions

  • Aztreonam
    1gm solution reconstituted

  • Aztreonam
    2gm solution reconstituted

How to take Aztreonam

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into a muscle or through a needle placed in one of your veins.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into a muscle or through a needle placed in one of your veins.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Aztreonam

Aztreonam contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to aztreonam.

Aztreonam warnings

  • Tell your doctor if you are pregnant or breastfeeding, you have kidney or liver disease, or you had an allergic reaction to penicillin or any medicine to treat an infection (such as cefaclor, cephalexin, imipenem, meropenem).

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Chest pain, shortness of breath, trouble breathing, wheezing

  • Dark urine or pale stools

  • Nausea, vomiting, loss of appetite, or stomach pain

  • Numbness, tingling, pain, burning, weakness, or loss of feeling anywhere in your body

  • Seizure, confusion, lightheadedness, fainting

  • Swelling of your face, throat, or lips

  • Swelling, pain, or redness near where the needle is placed

  • Unusual bleeding, bruising, or weakness

  • Vomiting of blood or material that looks like coffee grounds

  • Warmth or redness in your face, neck, arms, or upper chest

  • Yellowing of your skin or the whites of your eyes

Aztreonam interactions

  • Some medicines can affect how aztreonam works. Tell your doctor if you are using furosemide or probenecid.

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Aztreonam side effects

Serious Side Effects

  • Chest pain, shortness of breath, trouble breathing, wheezing

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Bloody or black, tarry stools, or diarrhea that may contain blood

  • Change in how much or how often you urinate

  • Seizure, confusion, lightheadedness, fainting

  • Dark urine or pale stools

  • Unusual bleeding, bruising, or weakness

  • Nausea, vomiting, loss of appetite, or stomach pain

  • Vomiting of blood or material that looks like coffee grounds

  • Swelling of your face, throat, or lips

  • Warmth or redness in your face, neck, arms, or upper chest

  • Swelling, pain, or redness near where the needle is placed

  • Yellowing of your skin or the whites of your eyes

  • Numbness, tingling, pain, burning, weakness, or loss of feeling anywhere in your body

Less Serious Side Effects

  • Sores or white patches in your mouth or throat

  • Mild diarrhea, constipation, or upset stomach

  • Trouble sleeping

  • Muscle pain, or pain where the shot was given