Bufferin is a brand-name, over-the-counter pain relief medication to relieve headache, joint pain, muscle pain, arthritis, or the common cold. The active ingredient in Bufferin, aspirin, blocks the body's production of substances that cause swelling, pain, or fever. Bufferin price averages $8.97, but a SingleCare Bufferin coupon reduces the price of 30, 325mg tablets down to $6.45. You can use SingleCare coupons on over-the-counter products, like Bufferin, when prescribed by a physician.
Edit your dosage
14 tablet, 325mgEdit
Show this free card to your pharmacist.
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
Members save the most
4.8 average rating
Bufferin is a brand-name, over-the-counter pain relief medication to relieve headache, joint pain, muscle pain, arthritis, or the common cold. The active ingredient in Bufferin, aspirin, blocks the body's production of substances that cause swelling, pain, or fever. Bufferin price averages $8.97, but a SingleCare Bufferin coupon reduces the price of 30, 325mg tablets down to $6.45. You can use SingleCare coupons on over-the-counter products, like Bufferin, when prescribed by a physician.
Bufferin is a brand-name, over-the-counter pain relief medication to relieve headache, joint pain, muscle pain, arthritis, or the common cold. The active ingredient in Bufferin, aspirin, blocks the body's production of substances that cause swelling, pain, or fever. Bufferin price averages $8.97, but a SingleCare Bufferin coupon reduces the price of 30, 325mg tablets down to $6.45. You can use SingleCare coupons on over-the-counter products, like Bufferin, when prescribed by a physician.
On average, the price for Bufferin is $8.97 per 30, 325mg tablets. Bufferin prices vary by pharmacy, quantity, and dosage. SingleCare discounts are eligible on over-the-counter products prescribed by a doctor. With a prescription and a SingleCare coupon for Bufferin, Bufferin costs $6.45.
Bufferin is not covered by prescription drug insurance, so you will always pay full price for Bufferin rather than a copay price. With SingleCare, however, the Bufferin price is $6.45 per 30, 325mg tablets if accompanied by a doctor's prescription.
Because Bufferin is an inexpensive over-the-counter pain reliever with many less expensive generic alternatives, neither Medicare Advantage nor Medicare Part D cover Bufferin.
One option for Medicare-eligible patients with a prescription for Bufferin can be found with a SingleCare savings card. The cost of Bufferin with a SingleCare discount card is $6.45.
Bufferin is a brand name analgesic, but there are numerous brand-name and generic alternatives. Brand names include Kirkland, Equate, Up & Up, Sunmark, and dozens of others.
Bufferin is a brand-name, over-the-counter pain relief medication to relieve headache, joint pain, muscle pain, arthritis, or the common cold. The active ingredient in Bufferin, aspirin, belongs to a class of drugs called non-steroidal anti-inflammatory drugs. Aspirin blocks the body's production of substances that cause swelling, and so reduces symptoms associated with swelling, such as pain or fever.
Aspirin is also a blood thinner and prevents blood clots from forming in the bloodstream. Bufferin is sometimes advised or prescribed to patients as an “aspirin regimen” to prevent stroke, heart attack, lung blood clots, leg blood clots, or other blood clotting problems.
Aspirin's most common side effects are stomach upset, heartburn, and stomach pain. Other common side effects of Bufferin include drowsiness, headache, or trouble sleeping. Allergic reactions are rare and include skin rash. This is not a complete list of the Bufferin side effects.
SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
