What is Caffeine Citrate: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Caffeine Citrate overview

BRAND NAMES:

  • Caffeine Citrate Novaplus

Generic Names:

  • Caffeine Citrate

Uses:

  • Treats breathing problems in premature babies.

Therapeutic Classes:

  • Stimulant, Respiratory

Forms:

  • Liquid

How it’s taken:

  • By mouth

What is Caffeine Citrate used for?

Cafcit is an oral suspension used for the short term treatment of breathing problems in premature infants and to improve alertness in children. This drug is not for use by adults and may cause side effects such as restlessness, vomiting, nausea and dry skin.

What form(s) does Caffeine Citrate come in

  • Liquid

What are common Caffeine Citrate doses?

  • Vial 3ML of 20MG/ML

  • Vial 3ML of 60MG/3ML

Common Caffeine Citrate prescriptions

  • Caffeine Citrate
    3ml of 60mg/3ml vial

How to take Caffeine Citrate

  • Your child's doctor will tell you how much of this medicine to give and how often to give it. Do not give more medicine or give it more often than directed.

  • Each vial is for one use only. Throw away any leftover medicine after you have given the proper dose to your child.

  • Measure the medicine with a marked measuring spoon or medicine cup.

  • Missed dose: Give your child a dose as soon as you can. If it is almost time for your child's next dose, wait until then to give the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

  • Do not use the medicine if it has changed color or has anything floating in it. Throw the vial away and get a fresh one. Call your child's doctor or pharmacist for replacement instructions.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Each vial is for one use only. Throw away any leftover medicine after you have given the proper dose to your child.

  • Do not use the medicine if it has changed color or has anything floating in it. Throw the vial away and get a fresh one. Call your child's doctor or pharmacist for replacement instructions.

  • Your child's doctor will tell you how much of this medicine to give and how often to give it. Do not give more medicine or give it more often than directed.

  • Missed dose: Give your child a dose as soon as you can. If it is almost time for your child's next dose, wait until then to give the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

  • Measure the medicine with a marked measuring spoon or medicine cup.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Caffeine Citrate

Caffeine Citrate contraindications

  • This medicine is not right for everyone. Your child should not receive this medicine if he had an allergic reaction to caffeine.

Caffeine Citrate warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Unusual trouble sleeping, eating less than normal, irritability

  • Unusual body or muscle movements

  • Never give this medicine to a child it was not prescribed for.

  • Tell your child's doctor about any seizures, kidney problems, liver problems, blood sugar problems, or heart problems your child has had.

  • If your child continues to have breathing problems after receiving this medicine, call his doctor for instructions. Do not give more medicine.

  • Your child's blood will need to be checked at regular visits. Keep all appointments.

Caffeine Citrate interactions

  • Some medicines can affect how this medicine works. Tell your child's doctor if your child is also taking cimetidine, ketoconazole, phenobarbital, phenytoin, or theophylline, or if the child's mother consumed any caffeine within a few hours before giving birth.

  • If your child continues to have breathing problems after receiving this medicine, call his doctor for instructions. Do not give more medicine.

  • Your child's blood will need to be checked at regular visits. Keep all appointments.

  • Never give this medicine to a child it was not prescribed for.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Caffeine Citrate side effects

Serious Side Effects

  • Decrease or increase in the number of wet diapers in a day

  • Seizures

  • Fever

  • Unusual trouble sleeping, eating less than normal, irritability

  • Fast heartbeat

  • Bloated stomach, blood in the stools, feeding problems, yellow vomit, low body temperature

  • Unusual body or muscle movements

Less Serious Side Effects

  • Fussiness, restlessness, or excessive crying

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