What is Clopidogrel? Uses, warnings & side effects

How to take Clopidogrel

• Your doctor will tell you how much medicine to use. Do not use more than directed.

• Please read the Medication Guide that comes with the prescription.

• Do not miss a dose, and do not stop taking clopidogrel until talking to the doctor.

• Take all other drugs prescribed by your doctor such as aspirin.

• Clopidogrel tablets can be taken with food or on an empty stomach.

• Swallow the tablet whole with a drink of water.

• Store clopidogrel tablets at room temperature.

What to do if you miss a dose of Clopidogrel

• Take a missed dose as soon as it’s remembered.

• If it’s almost time for the next dose, skip the missed dose and take the next dose at its scheduled time.

• Do not take two tablets to make up for a missed dose.

Clopidogrel contraindications - Who shouldn't take Clopidogrel?

• This medicine is not right for everyone. 

• Do not use it if you are:

  • Allergic to clopidogrel

  • Experiencing active bleeding such as an ulcer or hemorrhage

Clopidogrel warnings

• Tell all doctors, dentists, and other healthcare professionals treating you that you are taking clopidogrel, particularly before invasive procedures such as dental procedures.

• Before taking clopidogrel, tell your doctor if you are pregnant, breastfeeding, or have:

  • Bleeding problems

  • Bowel or stomach ulcers 

  • A history of bleeding problems

• When taking clopidogrel, tell the prescriber about any future surgical or dental procedures.

• This medicine can cause you to bleed and bruise more easily. Take precautions to avoid injury. Immediately inform the prescriber if you have symptoms of bleeding.

• This medicine may cause a rare but serious blood clotting condition called thrombotic thrombocytopenic purpura. Immediately contact the prescriber if you experience symptoms such as red spots or purple patches on the skin, pale skin, or fever.

• Do not stop taking clopidogrel suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Clopidogrel interactions & what to avoid when taking Clopidogrel

• Tell the prescriber about all prescription drugs, over-the-counter medications, and supplements being taken, particularly:

  • Aspirin

  • Nonsteroidal anti-inflammatory drugs (NSAIDs)

  • Other blood thinners including warfarin

  • Antidepressants called selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs)

  • Opioids including some diarrhea medications

  • Esomeprazole, omeprazole, repaglinide, rifampin

• Make sure other prescribers know you are taking clopidogrel before they prescribe new medications.

Find more information about clopidogrel interactions to avoid here.