What is Cortrosyn: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Cortrosyn overview

BRAND NAMES:

  • Cortrosyn, Cosyntropin Novaplus

Generic Names:

  • Cosyntropin

Uses:

  • Used as part of a medical test of the adrenal glands.

Therapeutic Classes:

  • Diagnostic Agent, Diagnostic Agent, Adrenocortical Function, Endocrine-Metabolic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Cortrosyn used for?

What form(s) does Cortrosyn come in

  • Injectable

What are common Cortrosyn doses?

  • Solution Reconstituted 0.25MG

Common Cortrosyn prescriptions

  • Cortrosyn
    0.25mg solution reconstituted

How to take Cortrosyn

  • Injection routeA nurse or other health provider will give you this medicine.

  • An IV injection is given through a small tube that is put in one of your veins, usually in your arm, wrist, or hand.

  • An IM injection is a shot given in the muscle of your upper arm, thigh, or buttocks.

  • If you miss your appointment for this test, call your doctor.

  • An IV injection is given through a small tube that is put in one of your veins, usually in your arm, wrist, or hand.

  • An IM injection is a shot given in the muscle of your upper arm, thigh, or buttocks.

  • Injection routeA nurse or other health provider will give you this medicine.

  • If you miss your appointment for this test, call your doctor.

What to do if you miss a dose of Cortrosyn

Cortrosyn contraindications

  • This medicine is not right for everyone. You should not receive this medicine if you have had an allergic reaction to cosyntropin.

Cortrosyn warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you are allergic to corticotropins.

Cortrosyn interactions

  • Tell your doctor if you are also using a diuretic (water pill).

Cortrosyn side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

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