Cortrosyn Coupons & Prices

Cosyntropin

Cortrosyn is a brand-name prescription injection used to test the adrenal gland's ability to produce cortisol, a hormone essential to regulating many of the body's most vital functions. Cosyntropin, the active ingredient in Cortrosyn, works just like a natural hormone in the body by stimulating cortisol production in the adrenal glands. Cortrosyn is administered as an intramuscular injection for rapid testing or a slow infusion (4-8 hours) for a more precise test of adrenal gland function. The cost of Cortrosyn is normally $142.31 at full price. A SingleCare Cortrosyn coupon reduces that price to $34.55. Ask the case manager at the hospital or clinic where you receive your Cortrosyn injection if they will accept a SingleCare Cortrosyn coupon. If they do, you might pay only $34.55 for your injection.

Set your location
Get alerted when the price
changes more than 10%

0.25 solution reconstituted0.25mgEdit

Unlock members-only prices.Free signup.

You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.

Cortrosyn coupon at Walgreens Pharmacy
$37.55
$ 34.55
$3 off with signupwith signup

Show this free card to your pharmacist.

Coupon card loading
Cortrosyn coupon at CVS Pharmacy
$76.71
$ 73.71
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Cortrosyn coupon at Publix Pharmacy
$78.01
$ 75.01
$3 off with signupwith signup
Cortrosyn coupon at Kroger Pharmacy
$81.84
$ 78.84
$3 off with signupwith signup
Cortrosyn coupon at Harris Teeter Pharmacy
$81.84
$ 78.84
$3 off with signupwith signup
Cortrosyn coupon at Walmart Neighborhood Market Pharmacy
$83.99
$ 80.99
$3 off with signupwith signup
$83.99
$ 80.99
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/20/2025

Members save the most

Save big on your prescriptions
with the free SingleCare app.
4.8 average rating
About Cortrosyn

Cortrosyn is a brand-name prescription injection used to test the adrenal gland's ability to produce cortisol, a hormone essential to regulating many of the body's most vital functions. Cosyntropin, the active ingredient in Cortrosyn, works just like a natural hormone in the body by stimulating cortisol production in the adrenal glands. Cortrosyn is administered as an intramuscular injection for rapid testing or a slow infusion (4-8 hours) for a more precise test of adrenal gland function. The cost of Cortrosyn is normally $142.31 at full price. A SingleCare Cortrosyn coupon reduces that price to $34.55. Ask the case manager at the hospital or clinic where you receive your Cortrosyn injection if they will accept a SingleCare Cortrosyn coupon. If they do, you might pay only $34.55 for your injection.

Cortrosyn Price History & Information

Price History for Cortrosyn (Brand) & Cosyntropin (Generic)

1 count, solution reconstituted, 0.25mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Cortrosyn (Brand) & Cosyntropin (Generic)

1 count, solution reconstituted, 0.25mg
PharmacyCortrosyn Retail PriceCosyntropin Retail PriceCosyntropin SingleCare Price
CVS Pharmacy-$99.99$76.71
Walmart-$95.76$83.99
Walgreens$173.69--
Kroger Pharmacy$127.99$154.49$81.84

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Cortrosyn

Cortrosyn is a brand-name prescription injection used to test the adrenal gland's ability to produce cortisol, a hormone essential to regulating many of the body's most vital functions. Cosyntropin, the active ingredient in Cortrosyn, works just like a natural hormone in the body by stimulating cortisol production in the adrenal glands. Cortrosyn is administered as an intramuscular injection for rapid testing or a slow infusion (4-8 hours) for a more precise test of adrenal gland function. The cost of Cortrosyn is normally $142.31 at full price. A SingleCare Cortrosyn coupon reduces that price to $34.55. Ask the case manager at the hospital or clinic where you receive your Cortrosyn injection if they will accept a SingleCare Cortrosyn coupon. If they do, you might pay only $34.55 for your injection.

Cortrosyn FAQs

How much does Cortrosyn cost without insurance?

Cortrosyn costs around $142.31 for uninsured customers, but this price might vary. With a SingleCare Cortrosyn coupon, you could pay only $34.55 for 1, 0.25mg solution reconstituted of Cortrosyn if the clinic, doctor's office, or hospital where you receive Cortrosyn injections will accept SingleCare.

How much does Cortrosyn cost with insurance?

Your copay for Cortrosyn with insurance will vary depending on your plan and the price charged for Cortrosyn by the hospital or clinic where you get your injection. It may happen, though, that Cortrosyn will be covered by your health insurance as a medical benefit rather than a prescription drug benefit. Ask the clinic, doctor's office, or hospital where you receive Cortrosyn injections if they will accept a SingleCare Cortrosyn coupon. If so, you could pay only $34.55 for an injection.

Does Medicare cover Cortrosyn and how much does it cost?

Cortrosyn is usually not covered by Medicare Part D and Medicare Advantage prescription drug plans, but may be covered under Medicare Part B as a medical benefit. No matter what your coverage, ask the clinic, doctor's office, or hospital where you receive Cortrosyn injections if they will accept a SingleCare Cortrosyn coupon; you could pay only $34.55.

Is there a generic of Cortrosyn?

Cortrosyn is a brand-name prescription drug with tetracosactide (cosyntropin) as the active ingredient. Generic cosyntropin is available from Sandoz and Mylan. You can search the SingleCare website or app for cosyntropin if you have any questions about it or need valuable savings coupons.

What is Cortrosyn?

Cortrosyn is a brand-name prescription injection used to test the adrenal gland's ability to produce cortisol, a hormone that is essential to many of the body's functions, such as regulating blood sugar, cell functions, reducing swelling, controlling water levels in the body, and memory function. Cortisol is also essential to the body's handling of stress. The pituitary gland produces a hormone, ACTH, which attaches to cells on the adrenal gland and activates cortisol production by the adrenal glands.

Sometimes the body does not produce enough cortisol. This can be a serious and sometimes life-threatening condition. It is caused by problems with either the pituitary gland or the adrenal glands. Cortrosyn is administered to find out if low cortisol is due to the adrenal glands. Tetracosactide, also known as cosyntropin, works just like ACTH and stimulates the adrenal glands to produce cortisol. The doctor then tests to see if the adrenal gland is producing the expected amount of cortisol.

Cortrosyn is administered as two intramuscular injections for rapid testing or a slow infusion (four to eight hours) for a more precise test of adrenal gland function.

What are the side effects of Cortrosyn?

The most common side effects of Cortrosyn are reactions to the infusion or injections, including itching, rash, redness, or irritation. These reactions should fade in one or two days. Cortrosyn stimulates cortisol production, the so-called stress hormone. As a result, the most common side effects of Cortrosyn are stress responses, such as high blood pressure, rapid heartbeat, palpitations, flushing, and anxiety. Cortrosyn also causes swelling, dizziness, and trouble breathing. Allergic reactions are rare. The patient will be monitored throughout the process and after.

Where are Cortrosyn coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.