Cortrosyn is a brand-name prescription injection used to test the adrenal gland's ability to produce cortisol, a hormone essential to regulating many of the body's most vital functions. Cosyntropin, the active ingredient in Cortrosyn, works just like a natural hormone in the body by stimulating cortisol production in the adrenal glands. Cortrosyn is administered as an intramuscular injection for rapid testing or a slow infusion (4-8 hours) for a more precise test of adrenal gland function. The cost of Cortrosyn is normally $142.31 at full price. A SingleCare Cortrosyn coupon reduces that price to $34.55. Ask the case manager at the hospital or clinic where you receive your Cortrosyn injection if they will accept a SingleCare Cortrosyn coupon. If they do, you might pay only $34.55 for your injection.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/20/2025
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Cortrosyn is a brand-name prescription injection used to test the adrenal gland's ability to produce cortisol, a hormone essential to regulating many of the body's most vital functions. Cosyntropin, the active ingredient in Cortrosyn, works just like a natural hormone in the body by stimulating cortisol production in the adrenal glands. Cortrosyn is administered as an intramuscular injection for rapid testing or a slow infusion (4-8 hours) for a more precise test of adrenal gland function. The cost of Cortrosyn is normally $142.31 at full price. A SingleCare Cortrosyn coupon reduces that price to $34.55. Ask the case manager at the hospital or clinic where you receive your Cortrosyn injection if they will accept a SingleCare Cortrosyn coupon. If they do, you might pay only $34.55 for your injection.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Cortrosyn Retail Price | Cosyntropin Retail Price | Cosyntropin SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | - | $99.99 | $76.71 |
| Walmart | - | $95.76 | $83.99 |
| Walgreens | $173.69 | - | - |
| Kroger Pharmacy | $127.99 | $154.49 | $81.84 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Cortrosyn is a brand-name prescription injection used to test the adrenal gland's ability to produce cortisol, a hormone essential to regulating many of the body's most vital functions. Cosyntropin, the active ingredient in Cortrosyn, works just like a natural hormone in the body by stimulating cortisol production in the adrenal glands. Cortrosyn is administered as an intramuscular injection for rapid testing or a slow infusion (4-8 hours) for a more precise test of adrenal gland function. The cost of Cortrosyn is normally $142.31 at full price. A SingleCare Cortrosyn coupon reduces that price to $34.55. Ask the case manager at the hospital or clinic where you receive your Cortrosyn injection if they will accept a SingleCare Cortrosyn coupon. If they do, you might pay only $34.55 for your injection.
Cortrosyn costs around $142.31 for uninsured customers, but this price might vary. With a SingleCare Cortrosyn coupon, you could pay only $34.55 for 1, 0.25mg solution reconstituted of Cortrosyn if the clinic, doctor's office, or hospital where you receive Cortrosyn injections will accept SingleCare.
Your copay for Cortrosyn with insurance will vary depending on your plan and the price charged for Cortrosyn by the hospital or clinic where you get your injection. It may happen, though, that Cortrosyn will be covered by your health insurance as a medical benefit rather than a prescription drug benefit. Ask the clinic, doctor's office, or hospital where you receive Cortrosyn injections if they will accept a SingleCare Cortrosyn coupon. If so, you could pay only $34.55 for an injection.
Cortrosyn is usually not covered by Medicare Part D and Medicare Advantage prescription drug plans, but may be covered under Medicare Part B as a medical benefit. No matter what your coverage, ask the clinic, doctor's office, or hospital where you receive Cortrosyn injections if they will accept a SingleCare Cortrosyn coupon; you could pay only $34.55.
Cortrosyn is a brand-name prescription drug with tetracosactide (cosyntropin) as the active ingredient. Generic cosyntropin is available from Sandoz and Mylan. You can search the SingleCare website or app for cosyntropin if you have any questions about it or need valuable savings coupons.
Cortrosyn is a brand-name prescription injection used to test the adrenal gland's ability to produce cortisol, a hormone that is essential to many of the body's functions, such as regulating blood sugar, cell functions, reducing swelling, controlling water levels in the body, and memory function. Cortisol is also essential to the body's handling of stress. The pituitary gland produces a hormone, ACTH, which attaches to cells on the adrenal gland and activates cortisol production by the adrenal glands.
Sometimes the body does not produce enough cortisol. This can be a serious and sometimes life-threatening condition. It is caused by problems with either the pituitary gland or the adrenal glands. Cortrosyn is administered to find out if low cortisol is due to the adrenal glands. Tetracosactide, also known as cosyntropin, works just like ACTH and stimulates the adrenal glands to produce cortisol. The doctor then tests to see if the adrenal gland is producing the expected amount of cortisol.
Cortrosyn is administered as two intramuscular injections for rapid testing or a slow infusion (four to eight hours) for a more precise test of adrenal gland function.
The most common side effects of Cortrosyn are reactions to the infusion or injections, including itching, rash, redness, or irritation. These reactions should fade in one or two days. Cortrosyn stimulates cortisol production, the so-called stress hormone. As a result, the most common side effects of Cortrosyn are stress responses, such as high blood pressure, rapid heartbeat, palpitations, flushing, and anxiety. Cortrosyn also causes swelling, dizziness, and trouble breathing. Allergic reactions are rare. The patient will be monitored throughout the process and after.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved