Culturelle Immune Defense is a dietary supplement that can be taken to boost your immune system. This next-generation immune system support contains vitamins and minerals, antioxidants, and probiotics. It is also safe for use by adults and children 12 years and older. There is currently no generic version of Culturelle Immune Defense. However, 3, 10 capsules bottles of Culturelle Immune Defense can be purchased as an over-the-counter product for about $31.88. You can reduce the retail price of Culturelle Immune Defense when you use a SingleCare Culturelle Immune Defense coupon every time you shop at participating pharmacies and spend only $7.04 for 0.3, 100 tablets chewable bottle.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/07/2026
Culturelle Immune Defense is a dietary supplement that can be taken to boost your immune system. This next-generation immune system support contains vitamins and minerals, antioxidants, and probiotics. It is also safe for use by adults and children 12 years and older. There is currently no generic version of Culturelle Immune Defense. However, 3, 10 capsules bottles of Culturelle Immune Defense can be purchased as an over-the-counter product for about $31.88. You can reduce the retail price of Culturelle Immune Defense when you use a SingleCare Culturelle Immune Defense coupon every time you shop at participating pharmacies and spend only $7.04 for 0.3, 100 tablets chewable bottle.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Culturelle Immune Defense Retail Price | Culturelle Immune Defense SingleCare Price |
|---|---|---|
| Walmart | - | - |
| Walgreens | $15.00 | $14.70 |
| Kroger Pharmacy | - | - |
| Albertsons Pharmacy | - | - |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Culturelle Immune Defense is a dietary supplement that can be taken to boost your immune system. This next-generation immune system support contains vitamins and minerals, antioxidants, and probiotics. It is also safe for use by adults and children 12 years and older. There is currently no generic version of Culturelle Immune Defense. However, 3, 10 capsules bottles of Culturelle Immune Defense can be purchased as an over-the-counter product for about $31.88. You can reduce the retail price of Culturelle Immune Defense when you use a SingleCare Culturelle Immune Defense coupon every time you shop at participating pharmacies and spend only $7.04 for 0.3, 100 tablets chewable bottle.
The average cost of Culturelle Immune Defense without insurance may be around $31.88 or more. You can pay only $7.04 for Culturelle Immune Defense when you use a SingleCare Culturelle Immune Defense discount card with your purchase. These prescription savings can be redeemed at a number of popular drugstores such as CVS Pharmacy, Walmart, Kroger, and Walgreens.
How much you pay for Culturelle Immune Defense with insurance will depend on whether this dietary supplement is covered by your insurance plan. You can ask an insurance agent or healthcare provider about your insurance options but Culturelle Immune Defense retails for about $31.88. To save instantly on the cash price of Culturelle Immune Defense when you use a coupon for Culturelle Immune Defense from SingleCare. With our Culturelle Immune Defense coupon you pay the reduced price of $7.04 for your refill. Your pharmacist can help you to compare prices to find the lowest price for this immune system booster.
Medicare does not currently offer coverage for Culturelle Immune Defense. However, you can still save money on your out-of-pocket costs for Culturelle Immune Defense by using SingleCare as your copay. With our prescription savings card, you pay our lowest price of $7.04 for your Culturelle Immune Defense refill at your local drugstore.
Culturelle Immune Defense is a brand-name product that is manufactured by i-Health, Inc. Currently, there is not a generic version of Culturelle Immune Defense available in the United States. Other products under the Culturelle brand include Culturelle Probiotics Pro-Well and Culturelle Probiotics Digestive Health.
Culturelle Advanced Immune Defense is a dietary supplement that can be taken to boost your immune system. This next-generation immune system support contains vitamins and minerals such as vitamin C and Zinc, antioxidants, and probiotics such as lactobacillus GG and bifidobacterium. Probiotics also help to support digestive health. Culturelle Immune Defense is dairy-free, lactose-free, gluten-free, and preservative-free. Culturelle Immune Defense is also safe for use by adults and children 12 years and older. However, people with an immuno-deficiency disorder should use Culturelle Immune Defense unless you are directed by your healthcare provider.
Do not use Culturelle Immune Defense if you are allergic to any of its ingredients.
Before using Culturelle Immune Defense tell your doctor about any other medical conditions you may have or are being treated for. You should also tell your healthcare provider about all the medications you are using including all prescription drugs, over-the-counter medicines, and other supplements.
You should only use Culturelle Immune Defense as directed by your healthcare provider or according to the directions for use provided on the packaging. One Culturelle Immune Defense capsule is usually taken daily.
Keep Culturelle Immune Defense out of the reach of children and pets.
Common side effects of Culturelle Immune Defense include gas or bloating. If these side effects do not go away or get worse, contact your healthcare provider right away.
Although rare, you could get a serious allergic reaction to Culturelle Immune Defense. Signs of an allergic reaction include hives, rash, itching, peeling or blistered skin, trouble breathing, and swelling of your face, lips, throat, and tongue.
This is not a complete list of the possible side effects of Culturelle Immune Defense and others can occur. You can talk to your healthcare provider about any concerns you may have to ensure Culturelle Immune Defense is right for you. You may also report any side effects to the FDA.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved