Vyzulta is a prescription medication used to reduce eye pressure in people with open-angle glaucoma or ocular hypertension. It comes as an ophthalmic solution that contains the active ingredient latanoprostene bunod. Vyzulta works as a prostaglandin analog. No generic version of Vyzulta is currently available in the United States. The average cash price of Vyzulta is $347.33 for 2.50, 0.024% solution (quantity in ml)s. You may be able to lower the retail price of Vyzulta to $255.46 for 2.5, 0.024% solution (quantity in ml)s with a free SingleCare discount card at a participating pharmacy.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/18/2025
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Vyzulta is a prescription medication used to reduce eye pressure in people with open-angle glaucoma or ocular hypertension. It comes as an ophthalmic solution that contains the active ingredient latanoprostene bunod. Vyzulta works as a prostaglandin analog. No generic version of Vyzulta is currently available in the United States. The average cash price of Vyzulta is $347.33 for 2.50, 0.024% solution (quantity in ml)s. You may be able to lower the retail price of Vyzulta to $255.46 for 2.5, 0.024% solution (quantity in ml)s with a free SingleCare discount card at a participating pharmacy.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Vyzulta Retail Price | Vyzulta SingleCare Price |
|---|---|---|
| CVS Pharmacy | $307.93 | $284.40 |
| Walmart | $311.00 | $276.71 |
| Walgreens | $315.06 | $276.48 |
| Kroger Pharmacy | $311.00 | $257.51 |
| Albertsons Pharmacy | $321.70 | $279.58 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Vyzulta is a prescription medication used to reduce eye pressure in people with open-angle glaucoma or ocular hypertension. It comes as an ophthalmic solution that contains the active ingredient latanoprostene bunod. Vyzulta works as a prostaglandin analog. No generic version of Vyzulta is currently available in the United States. The average cash price of Vyzulta is $347.33 for 2.50, 0.024% solution (quantity in ml)s. You may be able to lower the retail price of Vyzulta to $255.46 for 2.5, 0.024% solution (quantity in ml)s with a free SingleCare discount card at a participating pharmacy.
Without insurance, the average retail price of Vyzulta is $347.33 for 2.50, 0.024% solution (quantity in ml)s. Prices can vary based on pharmacy location and prescribed quantity. It may be wise to check with your pharmacy for the most recent information on your prescription medication costs. SingleCare may help bring the cost down, with a Vyzulta coupon reducing the price to $255.46 for 2.5, 0.024% solution (quantity in ml)s.
The cost of Vyzulta with insurance can vary depending on the plan and your coverage stage, among other factors. You may be responsible for a copay or coinsurance amount based on your coverage stage. Consult your health insurance plan’s provider or your local pharmacist for detailed information about the cost of Vyzulta with your plan.
Some Medicare plans may cover Vyzulta. However, Vyzulta costs with Medicare will vary by plan, prescription, and coverage stage. Refer to your plan’s drug formulary to find out whether your Medicare Part D or Medicare Advantage plan covers Vyzulta. If Vyzulta is not covered by Medicare or if you have not met your plan’s deductible, you may have to pay the full price of $347.33 for 2.50, 0.024% solution (quantity in ml)s. With a SingleCare prescription discount card, you could owe as little as $255.46 for 2.5, 0.024% solution (quantity in ml)s.
A Vyzulta manufacturer coupon may be available to eligible commercially insured or cash-paying patients. In addition, a patient assistance program may be available that may help eligible patients receive Vyzulta at a discount or for free. Check with the manufacturer for eligibility requirements.
You may also be able to redeem savings using a SingleCare Vyzulta coupon. The card is free to download and could save you up to 80% on your prescription drugs at participating pharmacies. Visit the SingleCare website for more details.
A generic version of Vyzulta prescription drug is currently unavailable. The patent for Vyzulta as a brand-name drug expires in 2025. A generic version may not be available until late 2025 at the earliest.
Vyzulta is a brand-name drug manufactured by Bausch & Lomb Inc. It is FDA-approved to treat high pressure within the eyes (intraocular pressure) in individuals with open-angle glaucoma or ocular hypertension. High eye pressure can lead to a gradual loss of vision if left untreated. Vyzulta works by draining fluid (aqueous humor) from the eyes to maintain normal pressure. It is administered as an eye drop solution.
Vyzulta is approved for use by patients older than 16 years of age and is available as an ophthalmic solution. Vyzulta is typically administered as one drop in the affected eye or eyes once daily in the evening. The eye drops solution contains 0.24 mg of latanoprostene bunod per mL in either a 2.5 mL or 5 mL bottle.
Vyzulta should only be used as prescribed by a doctor or healthcare provider. Remove contact lenses before applying Vyzulta to the eyes. After using this prescription drug, wait several minutes for your vision to clear before driving or operating machinery.
Like any medication, Vyzulta may have side effects. The most common side effects of {{drug}} can include:
Eye redness
Eye irritation
Eye pain
Increased pigmentation (brown color) of the iris and eyelid skin
Growth of eyelashes
Eyelash changes are reversible upon discontinuing treatment. Other side effects may include blurred vision and a sensation of a foreign object in the eyes. Consult your doctor or healthcare provider for medical advice and additional information regarding other possible side effects of Vyzulta. Contact your healthcare provider if side effects occur, worsen, or persist after using Vyzulta.
Get emergency medical attention if you notice signs of an allergic reaction to Vyzulta. Signs and symptoms of an allergic reaction may include difficulty breathing, hives, and swelling of the face, lips, tongue, or throat.
Tell your healthcare provider if you are pregnant or plan to become pregnant. It is unknown whether Vyzulta will be harmful to an unborn baby. Tell your healthcare provider if you are breastfeeding as it is unknown if Vyzulta can pass into breast milk.
Tell your healthcare provider about any eye conditions you may have experienced in the past. You should also provide your healthcare provider with a list of medications that you are currently taking, such as other prescription medications, over-the-counter medications, herbal supplements, or vitamins.
As glaucoma is a chronic eye condition, Vyzulta is typically used as a long-term medication. However, the length of use of Vyzulta will depend on your healthcare provider’s instructions and the condition being treated. It's typically used once a day in the affected eye, in the evening. Always use this medication as directed by your healthcare provider.
Vyzulta is typically taken in the evening. The body makes less eye fluid (known as aqueous humor) at night. Using this medicine in the evening may help reduce the fluid even more when its production is already low, making it better at lowering pressure in the eye. Follow the instructions given by your healthcare provider or pharmacist regarding the timing and frequency of use.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
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© 2025 SingleCare Administrators. All rights reserved