What is Diprolene: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Diprolene overview

BRAND NAMES:

  • Diprolene, Diprolene AF, Diprolene AF

Generic Names:

  • Betamethasone Dipropionate Aug

Uses:

  • Relieves skin pain, swelling, and itching. This medicine is a corticosteroid.

Therapeutic Classes:

  • Corticosteroid, Very Strong

Forms:

  • Cream, Gel/Jelly, Lotion, Ointment

How it’s taken:

  • On the skin

What is Diprolene used for?

Diprolene is a topical steroid medication that reduces the actions of chemicals in the body that cause inflammation, redness, and swelling. It is used to treat several skin conditions including eczema, psoriasis, or allergic reactions.

What form(s) does Diprolene come in

  • Cream

  • Gel/Jelly

  • Lotion

  • Ointment

What are common Diprolene doses?

  • Tube 15GM of 0.05%

  • Tube 50GM of 0.05%

Common Diprolene prescriptions

  • Diprolene
    60ml of 0.05% bottle

  • Diprolene
    15gm of 0.05% tube

  • Diprolene
    50gm of 0.05% tube

How to take Diprolene

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • This medicine is not for long-term use. Do not use this medicine for longer than 2 weeks unless directed by your doctor.

  • Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.

  • Topical application routeWash your hands with soap and water before and after you use this medicine.

  • Topical application routeApply a thin layer of the medicine to the affected area. Rub it in gently.

  • Topical application routeDo not cover the treated area with a bandage unless directed by your doctor.

  • Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Topical application routeDo not cover the treated area with a bandage unless directed by your doctor.

  • Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Topical application routeWash your hands with soap and water before and after you use this medicine.

  • Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • This medicine is not for long-term use. Do not use this medicine for longer than 2 weeks unless directed by your doctor.

  • Topical application routeApply a thin layer of the medicine to the affected area. Rub it in gently.

What to do if you miss a dose of Diprolene

Diprolene contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to betamethasone or to other corticosteroids.

Diprolene warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell your doctor if you are pregnant or breastfeeding.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Diprolene interactions

  • Some medicines can affect how betamethasone works. Tell your doctor if you are using another steroid medicine, such as hydrocortisone, methylprednisolone, or prednisone.

  • Topical application routeDo not put cosmetics or skin care products on the treated skin.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Diprolene side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Headache and vision problems

  • Signs of skin infection, such as swelling, redness, warmth, pus, or oozing

  • Weight gain around your neck, upper back, face, or waist

Less Serious Side Effects

  • Itching or redness around your lips

  • Skin redness, pain, itching, irritation, discoloration, or dryness

  • Excessive hair growth

  • Increased thirst or appetite

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