Bupropion SR Coupons & Prices

Wellbutrin Sr

Bupropion extended-release (sustained release) is a commonly-prescribed atypical antidepressant—an FDA-approved drug that treats depression but works differently than other antidepressants. On average, Bupropion SR costs $98.06 per 60, 150mg tablets without insurance. With SingleCare, Bupropion SR can cost as little as $6.20 for 60, 150mg tablets.

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Bupropion SR coupon at Kroger Pharmacy
$9.20
$ 6.20
$3 off with signupwith signup

Show this free card to your pharmacist.

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Bupropion SR coupon at Harris Teeter Pharmacy
$9.20
$ 6.20
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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and it's free to join

Bupropion SR coupon at Walmart Neighborhood Market Pharmacy
$ 15.00
Bupropion SR coupon at Walmart Pharmacy
$ 15.00
Bupropion SR coupon at Food Lion Pharmacy
$ 17.41
Bupropion SR coupon at Costco Pharmacy
$ 17.66
$ 18.29
$23.33
$ 20.33
$3 off with signupwith signup
$26.46
$ 23.46
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Bupropion SR

Bupropion extended-release (sustained release) is a commonly-prescribed atypical antidepressant—an FDA-approved drug that treats depression but works differently than other antidepressants. On average, Bupropion SR costs $98.06 per 60, 150mg tablets without insurance. With SingleCare, Bupropion SR can cost as little as $6.20 for 60, 150mg tablets.

Bupropion SR Price History & Information

Price History for Bupropion Hcl Er (Sr) (Generic) & Wellbutrin Sr (Brand)

60 count, tablet extended release 12 hour, 150mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Bupropion Hcl Er (Sr) (Generic) & Wellbutrin Sr (Brand)

60 count, tablet extended release 12 hour, 150mg
PharmacyWellbutrin Sr Retail PriceBupropion Hcl Er (Sr) Retail PriceBupropion Hcl Er (Sr) SingleCare Price
CVS Pharmacy$559.20$93.00$44.60
Walmart-$30.90$23.40
Walgreens$595.80$15.28$12.41
Kroger Pharmacy$596.40$91.50$7.97
Albertsons Pharmacy-$85.20$15.36

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Bupropion SR

Bupropion extended-release (sustained release) is a commonly-prescribed atypical antidepressant—an FDA-approved drug that treats depression but works differently than other antidepressants. On average, Bupropion SR costs $98.06 per 60, 150mg tablets without insurance. With SingleCare, Bupropion SR can cost as little as $6.20 for 60, 150mg tablets.

Bupropion SR FAQs

How much is Bupropion SR with SingleCare?

The generic of Bupropion SR costs $6.20 for 60, 150mg tablets with a free Bupropion SR coupon from SingleCare. However, you could pay less depending on your Rx details. Use the dropdown menu above to enter your prescription information (i.e., brand/generic, form, dosage, quantity) to get the most accurate prices of Bupropion SR with SingleCare at your local pharmacies.

How much does Bupropion SR cost without insurance?

A 30-day supply of Bupropion SR costs $98.06 for 60, 150mg tablets without insurance coverage. By using a SingleCare prescription discount coupon for Bupropion SR, you could pay as little as $6.20 for 60, 150mg tablets of Bupropion SR.

How much does Bupropion SR cost with insurance?

Health insurance usually covers Bupropion SR without restrictions to treat depression. Although usually placed in the lowest copay tiers, the insurance plan may have additional out-of-pocket fees, such as deductibles or co-insurance. Ask the pharmacist to compare the price of Bupropion SR with the SingleCare Bupropion SR price. It may be cheaper to forego insurance and buy Bupropion SR with SingleCare. 

Does Medicare cover Bupropion SR?

Medicare Part D and most Medicare Advantage drug plans cover Bupropion SR. If the out-of-pocket expense is higher than expected, use a SingleCare Bupropion SR coupon without insurance. With SingleCare’s savings program, Bupropion SR can cost as little as $6.20 for 60, 150mg tablets.

Does Medicaid cover Bupropion SR?

Most people on Medicaid are covered for Bupropion SR, but formularies vary between states. If coverage is denied, use a SingleCare Bupropion SR coupon to lower the cash price of Bupropion SR to as low as $6.20 for 60, 150mg tablets.

What is the brand name for Bupropion SR?

The brand-name version of Bupropion SR is Wellbutrin SR. It’s a premium-priced drug, so people with a prescription for Wellbutrin could switch to generic Bupropion SR or use a prescription drug discount coupon from SingleCare. 

Ways to save on Bupropion SR

Bupropion SR is a middle-priced generic drug that may be challenging to pay for month after month. The surest way to save money on Bupropion SR is to use a SingleCare savings card at a participating pharmacy. SingleCare’s lowest price for Bupropion SR is $6.20 for 60, 150mg tablets. SingleCare members who join SingleCare’s bonus loyalty program can earn additional savings on future prescription drug purchases every time they use SingleCare’s discount program. 

Prescription savings can also be found by comparing prescription prices among pharmacies to find the lowest Bupropion SR price.

Other ways of saving include enrolling in Medicaid or Medicare Part D Extra Help. Community resources are also available, including 340B clinics or hospitals that could sell Bupropion SR at a government-subsidized price.

Is there a cheaper alternative to Bupropion SR?

Other atypical antidepressants that are cheaper than Bupropion SR are trazodone and mirtazapine. Both are commonly used for depression, but will vary in effectiveness and common side effects.

The lowest-priced antidepressants are tricyclic antidepressants, such as amitriptyline. They are among the most affordable prescription drugs available. However, they aren’t used as much as other antidepressants because of problems with effectiveness and side effects. 

SSRIs (selective serotonin reuptake inhibitors) are the first-line treatment for major depressive disorder. If they haven’t been tried, both fluoxetine and paroxetine have lower retail prices than Bupropion SR. 

Over-the-counter drugs or supplements that can help mood cannot be substituted for prescription drugs that treat depression or similar mental health problems.

All these drugs can be purchased at low prices using SingleCare drug coupons. However, everyone’s situation is different. Ask a healthcare professional for medical advice before switching to a lower-priced antidepressant. 

How to use SingleCare for Bupropion SR

SingleCare coupons are accepted at most major pharmacies and grocers, i.e., Walgreens, Kroger, Walmart, CVS, Safeway, and more. You can text, email, print, or save your free Bupropion SR coupon to your digital wallet and show a pharmacist when you pick up your prescription. 

Where are Bupropion SR coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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