What is Double Antibiotic: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Double Antibiotic overview

BRAND NAMES:

  • Double Antibiotic Ointment, Simply Neosporin, Polysporin

Generic Names:

  • Double Antibiotic

Uses:

  • Prevents infections caused by minor cuts, scrapes, and burns.

Therapeutic Classes:

  • Antibacterial Combination

Forms:

  • Ointment

How it’s taken:

  • On the skin

What is Double Antibiotic used for?

What form(s) does Double Antibiotic come in

  • Ointment

What are common Double Antibiotic doses?

  • Tube 14GM of 500-10000UNIT/GM

  • Tube 14.170000076293945GM of 500-10000UNIT/GM

  • Tube 28GM of 500-10000UNIT/GM

  • Tube 28.350000381469727GM of 500-10000UNIT/GM

  • Tube 28.399999618530273GM of 500-10000UNIT/GM

  • Packet 1 Ointment

Common Double Antibiotic prescriptions

  • Double Antibiotic
    1 ointment packet

  • Double Antibiotic
    14.2gm of 500-10000unit/gm tube

  • Double Antibiotic
    28.35gm of 500-10000unit/gm tube of ointment

  • Double Antibiotic
    28.4gm of 500-10000unit/gm tube of ointment

How to take Double Antibiotic

  • You may cover the treated area with a bandage.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Do not use this medicine in your eyes or over large areas of your body. Do not use it for longer than 7 days unless directed by your doctor.

  • Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

  • Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.

  • Clean your wound before you apply this medicine. Apply a small amount to the wound 1 to 3 times each day.

  • Missed dose:

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Topical application routeWash your hands with soap and water before and after you use this medicine.

  • Do not use this medicine in your eyes or over large areas of your body. Do not use it for longer than 7 days unless directed by your doctor.

  • Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Missed dose:

  • Clean your wound before you apply this medicine. Apply a small amount to the wound 1 to 3 times each day.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Topical application routeWash your hands with soap and water before and after you use this medicine.

  • You may cover the treated area with a bandage.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.

What to do if you miss a dose of Double Antibiotic

Double Antibiotic contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to bacitracin or polymyxin B.

Double Antibiotic warnings

  • Tell your doctor if you are pregnant or breastfeeding.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • This medicine is for use only on minor cuts or burns. Do not use it on an animal bite, deep or puncture wound, or a serious burn.

Double Antibiotic interactions

  • Topical application routeDo not put cosmetics or skin care products on the treated skin.

Double Antibiotic side effects

Serious Side Effects

  • Rash

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

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