Effaclar Duo is an over-the-counter acne spot gel. The active ingredients in Effaclar Duo are benzoyl peroxide and lipohydroxy acid, which combined kill bacteria, open pores, reduce skin swelling, and help remove excess or dead skin from the surface of affected areas. The retail price for Effaclar Duo is $38.55 at most major retailers and online stores. SingleCare discounts are eligible for over-the-counter products, like Effaclar Duo, when prescribed by a physician. With a prescription, a SingleCare Effaclar Duo coupon reduces the price of Effaclar Duo to $20.20 at major retailers, pharmacies, and supermarkets.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/12/2026
Effaclar Duo is an over-the-counter acne spot gel. The active ingredients in Effaclar Duo are benzoyl peroxide and lipohydroxy acid, which combined kill bacteria, open pores, reduce skin swelling, and help remove excess or dead skin from the surface of affected areas. The retail price for Effaclar Duo is $38.55 at most major retailers and online stores. SingleCare discounts are eligible for over-the-counter products, like Effaclar Duo, when prescribed by a physician. With a prescription, a SingleCare Effaclar Duo coupon reduces the price of Effaclar Duo to $20.20 at major retailers, pharmacies, and supermarkets.
Effaclar Duo is an over-the-counter acne spot gel. The active ingredients in Effaclar Duo are benzoyl peroxide and lipohydroxy acid, which combined kill bacteria, open pores, reduce skin swelling, and help remove excess or dead skin from the surface of affected areas. The retail price for Effaclar Duo is $38.55 at most major retailers and online stores. SingleCare discounts are eligible for over-the-counter products, like Effaclar Duo, when prescribed by a physician. With a prescription, a SingleCare Effaclar Duo coupon reduces the price of Effaclar Duo to $20.20 at major retailers, pharmacies, and supermarkets.
The price for Effaclar Duo averages around $38.55 at major retailers, but this price may vary by store and offers. With a SingleCare Effaclar Duo discount card, a prescription for 1, 40ml of 5.5% tube of Effaclar Duo costs $20.20. Before filling your next prescription, remember that a SingleCare savings card can save you as much as 80%.
Effaclar Duo is an over-the-counter facial acne treatment containing active ingredients widely available in other over-the-counter alternatives. Therefore, you will not find Effaclar Duo covered by insurance plans as you would a prescription drug with a copay. You can use a free Effaclar Duo coupon from SingleCare to save money on your prescription. The price of Effaclar Duo with a SingleCare savings card is only $20.20.
Because Effaclar Duo is a low-priced, over-the-counter acne remedy, no Medicare prescription drug plan covers purchases of Effaclar Duo. For Medicare patients with a prescription for Effaclar Duo, you’ll pay as little as $20.20 for 1, 40ml of 5.5% tube of Effaclar Duo with a SingleCare Effaclar Duo at major such as CVS, Longs Drugs, Fry's, and more.
Effaclar Duo is an acne spot treatment. Its active ingredients, benzoyl peroxide and lipohydroxy acid, are found separately and together in a wide range of over-the-counter brand-name and generic skin products. Search the SingleCare website or app to find information about and coupons for generic benzoyl peroxide was as well as other brand-name acne treatments.
Effaclar Duo is an over-the-counter spot gel to help treat and reduce facial acne. The active ingredients in Effaclar Duo are benzoyl peroxide and lipohydroxy acid.
Benzoyl peroxide is a widely used ingredient in over-the-counter and prescription acne medications. Benzoyl peroxide kills some of the bacteria that cause acne by increasing the amount of oxygen, toxic to the bacteria, in the skin. Benzoyl peroxide also opens pores, reduces skin swelling, and softens the outer layers of skin, making them easier to peel or rub off.
Lipohydroxy acid is another popular ingredient in acne and skin-care products that breaks down the connections between skin cells, allowing the outer surface of the skin to peel or rub off.
Benzoyl peroxide dries the skin. For this reason, Effaclar Duo also includes glycerin, a skin moisturizer that works by drawing moisture from the lower skin tissues to the outer layers of the skin.
As with any acne remedy, always wash and dry the affected area before applying Effaclar Duo. Apply Effaclar Duo sparingly only once or twice a day.
The active ingredients in Effaclar Duo produce few side effects, the most common being site reactions, such as skin irritation, burning, stinging, dry skin, peeling, flaking, redness, or allergic reactions, such as itchiness, rash, and swelling. You should discontinue Effaclar Duo if you experience any allergic reactions or if site reactions last too long.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved