Adapalene is a generic prescription drug approved by the FDA in the treatment of mild to moderate acne. This medication is classified as a retinoid and is similar to Vitamin A. Similar brand-name prescription medications include Differin. The average cash price of Adapalene is typically about $300.88. Customers can pay the lower price of $34.53 for 1, 45gm of 0.3% tube of gel when they use a SingleCare Adapalene coupon at their local CVS, Walmart, Kroger, and Walgreens.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 04/19/2026
Adapalene is a generic prescription drug approved by the FDA in the treatment of mild to moderate acne. This medication is classified as a retinoid and is similar to Vitamin A. Similar brand-name prescription medications include Differin. The average cash price of Adapalene is typically about $300.88. Customers can pay the lower price of $34.53 for 1, 45gm of 0.3% tube of gel when they use a SingleCare Adapalene coupon at their local CVS, Walmart, Kroger, and Walgreens.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Adapalene Retail Price | Adapalene SingleCare Price |
|---|---|---|
| CVS Pharmacy | $267.60 | $37.03 |
| Walmart | $250.87 | $48.60 |
| Walgreens | $300.15 | $65.66 |
| Kroger Pharmacy | $265.03 | $66.60 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Adapalene is a generic prescription drug approved by the FDA in the treatment of mild to moderate acne. This medication is classified as a retinoid and is similar to Vitamin A. Similar brand-name prescription medications include Differin. The average cash price of Adapalene is typically about $300.88. Customers can pay the lower price of $34.53 for 1, 45gm of 0.3% tube of gel when they use a SingleCare Adapalene coupon at their local CVS, Walmart, Kroger, and Walgreens.
If you do not have insurance coverage, the average retail cost for your Adapaleneprescription or refill may typically be around $300.88. Use a SingleCare Adapalene coupon at your local pharmacy and pay a discounted rate of $34.53 for 1, 45gm of 0.3% tube of gel. Remember to always bring your coupon to your local pharmacies including CVS Pharmacy, Kroger, Walmart Pharmacy, and Walgreens to save money on your prescription.
Depending on your type of insurance plan and level of coverage, the copay for Adapalene may vary. However, customers who use a SingleCare savings card can pay the reduced price of $34.53 for their prescription. Ask your local pharmacist to compare prices at checkout to maximize your savings.
Adapalene prescriptions may sometimes be covered by Medicare Part D and Medicare Advantage Plan. The Medicare copay can range from $15-$297. However, you may still save more with a SingleCare discount card at your local pharmacy. Customers can lower the price to $34.53 for 1, 45gm of 0.3% tube of gel of Adapalene with SingleCare.
Adapalene is the generic version while Differin is the brand-name version.
Adapalene is a generic medication approved by the FDA in the treatment of mild to moderate acne. This medication is classified as a retinoid and is similar to Vitamin A. Adapalene decreases the number and severity of pimples while increasing the healing of affected skin. It also relieves the acne symptoms of swelling and inflammation. This medication is recommended for children over the age of 12.
Always remember to read the instruction leaflet and to consult your dermatologist concerning the correct dosage and frequency for your medical condition. Adapalene is recommended to be applied once daily in the evening. It is a topical medicine and should avoid contact with mouth and eyes. Avoid contact with open wounds or skin that is dry, chapped, or sunburned. Always wash your hands and clean the area with a non-medicated skin cleanser Symptoms may appear to worsen at first before becoming better. Increasing dosage or frequency will not increase effectiveness. Consult your doctor before using Adapalene if you are pregnant or breastfeeding.
It is important to remember to consult your doctor about what medications and foods should be taken when using Adapalene in order to avoid side effects. The most common side effects include stinging, itching, redness, or dryness. Consult your doctor on how to treat side effects.
Severe allergic reactions to Adapalene are not common. However immediately contact your healthcare professional should you experience conjunctivitis, skin discoloration, dizziness, or trouble breathing. This is not a complete list of possible side effects. Seek medical advice before using Adapalene to determine if this drug is right for you.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved