Enstilar (calcipotriene and betamethasone dipropionate) is a topical medication containing a combination of a steroid and vitamin D analog. It is used to treat plaque psoriasis in adults and children over 12 years old. Enstilar helps reduce the thickening, redness, and scaling of the skin that occurs with psoriasis. It works by slowing down the growth of skin cells so that they do not build up and thicken. Enstilar is only available as a brand-name drug; there aren't any generic versions available. For a supply of 1, 60gm of 0.005-0.064% can, you should expect to pay an average cost of Enstilar around $1,832.06. You may be able to reduce this total to $1,159.20 by using a SingleCare Enstilar coupon at a participating neighborhood pharmacy.
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Prices updated: 05/04/2026
Enstilar (calcipotriene and betamethasone dipropionate) is a topical medication containing a combination of a steroid and vitamin D analog. It is used to treat plaque psoriasis in adults and children over 12 years old. Enstilar helps reduce the thickening, redness, and scaling of the skin that occurs with psoriasis. It works by slowing down the growth of skin cells so that they do not build up and thicken. Enstilar is only available as a brand-name drug; there aren't any generic versions available. For a supply of 1, 60gm of 0.005-0.064% can, you should expect to pay an average cost of Enstilar around $1,832.06. You may be able to reduce this total to $1,159.20 by using a SingleCare Enstilar coupon at a participating neighborhood pharmacy.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Enstilar Retail Price | Enstilar SingleCare Price |
|---|---|---|
| CVS Pharmacy | $1612.20 | $1217.40 |
| Walgreens | $1645.20 | $1411.80 |
| Kroger Pharmacy | $1640.40 | $1162.20 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Enstilar (calcipotriene and betamethasone dipropionate) is a topical medication containing a combination of a steroid and vitamin D analog. It is used to treat plaque psoriasis in adults and children over 12 years old. Enstilar helps reduce the thickening, redness, and scaling of the skin that occurs with psoriasis. It works by slowing down the growth of skin cells so that they do not build up and thicken. Enstilar is only available as a brand-name drug; there aren't any generic versions available. For a supply of 1, 60gm of 0.005-0.064% can, you should expect to pay an average cost of Enstilar around $1,832.06. You may be able to reduce this total to $1,159.20 by using a SingleCare Enstilar coupon at a participating neighborhood pharmacy.
If you do not have insurance coverage, Enstilar may cost around $1,832.06 or more. SingleCare can help you reduce the total cost of this prescription so you can save. Just use SingleCare's Enstilar coupon on your next Enstilar refill and pay a discounted total of just $1,159.20 for 1, 60gm of 0.005-0.064% can.
Prescription drug costs tend to vary based on the type of health insurance coverage that you're enrolled in. You may need to contact your health insurance provider directly to find out how much Enstilar costs under your coverage plan.
SingleCare's Enstilar discount cards may be much easier to use. A cost of $1,159.20 for 1, 60gm of 0.005-0.064% can is all you may have to pay for your Enstilar prescription when you use a SingleCare discount card at drugstores such as CVS Pharmacy and Walgreens.
Enstilar is covered by some Medicare insurance plans, but it can still be an expensive prescription drug. The average cost of Enstilar is $1,832.06. However, when you use a SingleCare Enstilar coupon, you could pay the lowest price of $1,159.20 for 1, 60gm of 0.005-0.064% can. SingleCare's savings coupons can be redeemed at pharmacies such as CVS, Kroger, Walgreens, and participating pharmacies.
Enstilar is a brand-name prescription drug. There is no generic alternative currently available.
Enstilar is an FDA-approved brand name drug used to treat the symptoms of psoriasis. It helps reduce redness, thickening, and scaling of the skin. Having healthy skin can help lower the risk of infection with psoriasis.
Enstilar contains a combination of betamethasone and calcipotriene. Betamethasone is a type of corticosteroid that helps to decrease inflammation, itching, and redness. Calcipotriene is a synthetic form of vitamin D that works by slowing the growth of skin cells.
Enstilar comes in the form of a topical foam spray, which is applied to the affected area of the skin. It is usually applied once daily to the affected area for up to four weeks. Consult your healthcare provider for the proper dosage requirements before using this medication. Do not apply this product to your groin area, face, or underarms.
Talk to your doctor or pharmacist before using Enstilar to learn about the possible side effects. Some common side effects of Enstilar include burning, itching, weight gain, redness, and irritation of the skin around areas where the medication is applied. Some people with psoriasis may experience serious side effects after using Enstilar. This medication may also cause hypopigmentation of the skin, or loss of color in the skin, especially in those with darker skin tones.
The use of Enstilar may also cause an increase in calcium levels in the blood (hypercalcemia). Contact your doctor immediately for professional medical advice if you notice signs of hypercalcemia, such as nausea, stomach upset, and unexplained constipation.
It’s possible to experience other side effects not listed here. Consult your health care professional for other possible Enstilar side effects, warnings, and precautions. Ask your doctor for medical advice before using this drug to ensure it’s the best treatment option for your condition.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
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