Learn more about entacapone
Entacapone is an FDA-approved, generic drug used in patients with Parkinson's disease who are experiencing levodopa “end-of-dose” recurrence of symptoms. Parkinson's is a progressive brain disorder that results in too little dopamine, a chemical critical to transmitting nerve signals, in the brain. Levodopa (in combination with carbidopa) is prescribed to replace dopamine, but symptoms return eventually for some patients near the end of the levodopa dose. Entacapone blocks an enzyme that breaks down dopamine and levodopa, so symptoms don't recur before the next dose of levodopa. The price of Entacapone is $321.94. However, a SingleCare Entacapone coupon reduces that retail price to $36.75 per 90, 200mg tablets. Find out more about this and other ways to save money in our FAQs.
Edit your dosage
Get alerted when the price
changes more than 10%
changes more than 10%
30 tablet, 200mgEdit
$39.75
$ 36.75
$3 off with signupwith signup
Show this free card to your pharmacist.
$40.78
$ 37.78
$3 off with signupwith signup
$40.78
$ 37.78
$3 off with signupwith signup
$ 51.06
$59.98
$ 56.98
$3 off with signupwith signup
$ 58.22
$70.55
$ 67.55
$3 off with signupwith signup
$70.55
$ 67.55
$3 off with signupwith signup
$214.67
$ 211.67
$3 off with signupwith signup
About SingleCare Pricing
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
Members save the most
Save big on your prescriptions
with the free SingleCare app.
4.8 average ratingText a link to get the app
About Entacapone
Entacapone is an FDA-approved, generic drug used in patients with Parkinson's disease who are experiencing levodopa “end-of-dose” recurrence of symptoms. Parkinson's is a progressive brain disorder that results in too little dopamine, a chemical critical to transmitting nerve signals, in the brain. Levodopa (in combination with carbidopa) is prescribed to replace dopamine, but symptoms return eventually for some patients near the end of the levodopa dose. Entacapone blocks an enzyme that breaks down dopamine and levodopa, so symptoms don't recur before the next dose of levodopa. The price of Entacapone is $321.94. However, a SingleCare Entacapone coupon reduces that retail price to $36.75 per 90, 200mg tablets. Find out more about this and other ways to save money in our FAQs.
Learn more about entacapone
Entacapone Price History & Information
Price History for Entacapone
90 count, tablet, 200mgOur price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
Average 1-Month Prices for Entacapone
90 count, tablet, 200mg| Pharmacy | Entacapone Retail Price | Entacapone SingleCare Price |
|---|---|---|
| CVS Pharmacy | $334.80 | $26.10 |
| Walmart | $358.20 | $39.60 |
| Kroger Pharmacy | $408.60 | $40.50 |
| Albertsons Pharmacy | $347.40 | $63.90 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
About Entacapone
Entacapone is an FDA-approved, generic drug used in patients with Parkinson's disease who are experiencing levodopa “end-of-dose” recurrence of symptoms. Parkinson's is a progressive brain disorder that results in too little dopamine, a chemical critical to transmitting nerve signals, in the brain. Levodopa (in combination with carbidopa) is prescribed to replace dopamine, but symptoms return eventually for some patients near the end of the levodopa dose. Entacapone blocks an enzyme that breaks down dopamine and levodopa, so symptoms don't recur before the next dose of levodopa. The price of Entacapone is $321.94. However, a SingleCare Entacapone coupon reduces that retail price to $36.75 per 90, 200mg tablets. Find out more about this and other ways to save money in our FAQs.
Entacapone FAQs
How much does Entacapone cost without insurance?
At most pharmacies, the cash price of Entacapone without insurance will be $321.94. A SingleCare prescription savings card lowers that cost to $36.75 (price may vary depending on the quantity prescribed).
How much does Entacapone cost with insurance?
Copay costs of Entacapone differ depending on your insurance plan. With SingleCare, Entacapone costs as little as $36.75 for 90, 200mg tablets. Ask your pharmacist to compare your insurance copay to your price using a SingleCare prescription discount card. Your SingleCare price could be lower.
Does Medicare cover Entacapone and how much does it cost?
Medicare Part D and Medicare Advantage prescription drug insurance plans provide insurance coverage for generic Entacapone, but usually do not provide coverage for the brand-name version, Comtan. If you don't have Medicare, SingleCare offers a discount coupon for Entacapone that every month reduces the cost of Entacapone to $36.75.
What is the brand name of Entacapone?
Entacapone is a generic prescription drug and is the active ingredient in the brand name prescription drug, Comtan.
What is Entacapone?
Entacapone is a generic prescription drug used in people with Parkinson's disease who begin to experience “end-of-dose wearing off” with levodopa. Parkinson's disease is a progressive brain disorder that causes involuntary muscle movements (dyskinesia), muscle stiffness, tremor, loss of coordination, and difficulty walking or balancing due to a shortage of dopamine, an important chemical for transmitting signals between nerve cells.
Levodopa (in combination with carbidopa) is prescribed to replace dopamine, but eventually, symptoms return for some patients near the end of the levodopa dose, that is, the levodopa wears off before the next dose. Entacapone blocks an enzyme that breaks down dopamine and levodopa, so symptoms don't recur before the next dose of levodopa.
What are the side effects of Entacapone?
While not a complete list of side effects, the most common side effects of Entacapone are involuntary muscle movements, slow movements, dry mouth, diarrhea or constipation, discoloration of urine, drowsiness, lightheadedness, dizziness, sweating, nausea, vomiting, abdominal pain, back pain, gas, stiff muscles, and muscle weakness. Mental and mood changes include confusion, agitation, unusual thoughts, unusual behaviors, anxiety, and hallucinations. Allergic reactions are rare, but discontinue Entacapone and get emergency medical help if there is any sign of an allergic reaction, such as hives, facial swelling, or difficulty breathing.
Consult your doctor or healthcare professional for additional information and medical advice regarding Entacapone.
Where are Entacapone coupons from SingleCare accepted?
SingleCare is accepted at most national pharmacies and grocers, including the following:
Subscribe to our savings newsletter
Health education, drug info, wellness & more
By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.
