Enulose is a brand-name prescription medication primarily used to treat portal-systemic encephalopathy, a condition that causes a loss of brain function due to the build-up of ammonia in the bloodstream from liver disease. The active ingredient in Enulose, lactulose, reduces ammonia in the bloodstream. Lactulose is more commonly used to treat constipation, so the manufacturer of Enulose, Teva, markets Constulose, a lactulose drug specifically to treat chronic constipation. On average, Enulose costs $56.48 but you could pay $8.31 for 473, 10gm/15ml solution (quantity in ml)s with a free SingleCare Enulose coupon.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Enulose is a brand-name prescription medication primarily used to treat portal-systemic encephalopathy, a condition that causes a loss of brain function due to the build-up of ammonia in the bloodstream from liver disease. The active ingredient in Enulose, lactulose, reduces ammonia in the bloodstream. Lactulose is more commonly used to treat constipation, so the manufacturer of Enulose, Teva, markets Constulose, a lactulose drug specifically to treat chronic constipation. On average, Enulose costs $56.48 but you could pay $8.31 for 473, 10gm/15ml solution (quantity in ml)s with a free SingleCare Enulose coupon.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Enulose Retail Price | Lactulose Encephalopathy Retail Price | Lactulose Encephalopathy SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $33.11 | - | - |
| Walmart | - | $33.11 | $28.38 |
| Walgreens | - | $40.68 | $14.19 |
| Kroger Pharmacy | - | $33.11 | $9.46 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Enulose is a brand-name prescription medication primarily used to treat portal-systemic encephalopathy, a condition that causes a loss of brain function due to the build-up of ammonia in the bloodstream from liver disease. The active ingredient in Enulose, lactulose, reduces ammonia in the bloodstream. Lactulose is more commonly used to treat constipation, so the manufacturer of Enulose, Teva, markets Constulose, a lactulose drug specifically to treat chronic constipation. On average, Enulose costs $56.48 but you could pay $8.31 for 473, 10gm/15ml solution (quantity in ml)s with a free SingleCare Enulose coupon.
Patients can usually expect to pay $56.48 for 473, 10gm/15ml solution (quantity in ml)s of Enulose. Compare this price to the cost of Enulose with a SingleCare coupon: $8.31 for 473, 10gm/15ml solution (quantity in ml)s. For all your prescription needs, a SingleCare savings card can save you as much as 80% on your purchases.
Check with your pharmacist about your copay for a Enulose prescription, since it can vary based on your insurance plan. Also, ask your pharmacist to compare your copay to your cost using a SingleCare Enulose coupon. At $8.31 for your Enulose prescription of 473, 10gm/15ml solution (quantity in ml)s, your SingleCare price may be lower.
Enulose is usually covered by Medicare Part D and Medicare Advantage prescription drug plans. People with Medicare can use a SingleCare Enulose coupon instead and lower their cost to as little as $8.31 for 473, 10gm/15ml solution (quantity in ml)s.
Enulose is a branded generic prescription drug with lactulose. The manufacturer, Teva, also offers another branded version of lactulose, Constulose, which is prescribed to treat chronic constipation. Another branded generic, Kristalose, is oral solution lactulose from Cumberland Pharmaceuticals. Generic versions of Enulose are more commonly sold as lactulose.
Enulose is a branded generic prescription drug that removes ammonia from the bloodstream in patients with portal-systemic encephalopathy. Caused by liver the disease, the ammonia build-up interferes with brain function and may result in coma. Enulose reduces ammonia by 25%-50% in 75% of patients with the condition.
Enulose is sometimes prescribed off-label as a laxative to relieve constipation. It functions as an osmotic laxative, drawing water from the intestinal linings to build up the water content of stools and provide lubrication.
The active ingredient in Enulose, lactulose, is a synthetic sugar similar to lactose, a sugar naturally present in milk. As a laxative, lactulose makes the colon contents acidic and draws water out of the colon tissues which bulk up stools. The higher acid content in the colon also draws ammonia out of the bloodstream. The ammonia gets trapped in the colon and the laxative properties of lactulose expel it quickly from the colon. Enulose does not treat the underlying liver problem.
Enulose is taken as an oral solution, usually two to three tablespoons two to three times a day. daily, and takes one or two days to produce effects.
The World Health Organization lists lactulose as one of the most safe and effective essential medicines. Side effects of Enulose are relatively minimal and include upset stomach, diarrhea, bloating, gas, nausea, and vomiting. Allergic reactions are rare and include itching, hives, swelling and skin rash. Enulose is chemically similar to lactose, so patients with lactose intolerance or allergies will be more likely to suffer side effects or allergic reactions. This is not a complete list of side effects that may occur. If you have concerns or questions about side effects, consult with your prescribing physician.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved