What is Euflexxa: Uses, Warnings & Interactions

What is Euflexxa: Uses, Warnings & Interactions

Updated May 14, 2025 • Published Jun 17, 2021

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Euflexxa overview

BRAND NAMES:

TriLURON, Durolane, Euflexxa, Gel-One, GelSyn-3, GenVisc 850, Hyalgan, Hymovis, Monovisc, TriVisc, Visco-3, Orthovisc, Supartz FX

Generic Names:

Euflexxa

Uses:

Treats severe pain in your knee due to osteoarthritis.

Therapeutic Classes:

Antirheumatic, Cartilaginous Defect Repair Agent, Musculoskeletal Agent

Forms:

Injectable

How it’s taken:

By injection

What is Euflexxa used for?

What form(s) does Euflexxa come in

Injectable

What are common Euflexxa doses?

Syringe 2ML of 20MG/2ML

Common Euflexxa prescriptions

Euflexxa
2ml of 20mg/2ml syringe

How to take Euflexxa

Your doctor will tell you how many injections you will need. This medicine is injected into your knee joint.
Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Euflexxa

Euflexxa contraindications

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to hyaluronic acid or if you have a bleeding disorder.

Euflexxa warnings

Rest your knee for 48 hours after you receive an injection. Do not do strenuous, weightbearing activities, such as jogging or tennis. Avoid activities that keep you standing for longer than 1 hour.
Tell your doctor if you are pregnant or breastfeeding, or if you have any allergies, including to birds, feathers, or eggs.

Euflexxa interactions

Tell your doctor if you are pregnant or breastfeeding, or if you have any allergies, including to birds, feathers, or eggs.
Rest your knee for 48 hours after you receive an injection. Do not do strenuous, weightbearing activities, such as jogging or tennis. Avoid activities that keep you standing for longer than 1 hour.

Euflexxa side effects

Serious Side Effects

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Pain, redness, or swelling where the medicine is injected

Less Serious Side Effects

Mild increase in pain or swelling in your knee
Pain, redness, or swelling where the medicine is injected