Ezetimibe-Simvastatin is a combination prescription drug that reduces “bad” cholesterol (LDL cholesterol) and fats (triglycerides) in the bloodstream, both of which increase the risk of stroke and heart attack. Ezetimibe-Simvastatin is prescribed to patients diagnosed with high cholesterol or who have inherited a high cholesterol condition. The active ingredients in Ezetimibe-Simvastatin both reduce the liver's production of cholesterol (simvastatin) and block the body's ability to absorb dietary cholesterol through the intestines (ezetimibe). Ezetimibe-Simvastatin's retail price is $771.93, but with a SingleCare Ezetimibe-Simvastatin coupon, the price is only $37.19. SingleCare Ezetimibe-Simvastatin coupons are welcomed at many local pharmacies, like CVS, Target, Kroger, and Harris Teeter, among others.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/20/2025
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Ezetimibe-Simvastatin is a combination prescription drug that reduces “bad” cholesterol (LDL cholesterol) and fats (triglycerides) in the bloodstream, both of which increase the risk of stroke and heart attack. Ezetimibe-Simvastatin is prescribed to patients diagnosed with high cholesterol or who have inherited a high cholesterol condition. The active ingredients in Ezetimibe-Simvastatin both reduce the liver's production of cholesterol (simvastatin) and block the body's ability to absorb dietary cholesterol through the intestines (ezetimibe). Ezetimibe-Simvastatin's retail price is $771.93, but with a SingleCare Ezetimibe-Simvastatin coupon, the price is only $37.19. SingleCare Ezetimibe-Simvastatin coupons are welcomed at many local pharmacies, like CVS, Target, Kroger, and Harris Teeter, among others.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Ezetimibe-Simvastatin Retail Price | Ezetimibe-Simvastatin SingleCare Price |
|---|---|---|
| CVS Pharmacy | $673.20 | $672.30 |
| Walmart | $534.60 | $77.40 |
| Walgreens | $609.30 | $72.00 |
| Kroger Pharmacy | $996.84 | $100.80 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Ezetimibe-Simvastatin is a combination prescription drug that reduces “bad” cholesterol (LDL cholesterol) and fats (triglycerides) in the bloodstream, both of which increase the risk of stroke and heart attack. Ezetimibe-Simvastatin is prescribed to patients diagnosed with high cholesterol or who have inherited a high cholesterol condition. The active ingredients in Ezetimibe-Simvastatin both reduce the liver's production of cholesterol (simvastatin) and block the body's ability to absorb dietary cholesterol through the intestines (ezetimibe). Ezetimibe-Simvastatin's retail price is $771.93, but with a SingleCare Ezetimibe-Simvastatin coupon, the price is only $37.19. SingleCare Ezetimibe-Simvastatin coupons are welcomed at many local pharmacies, like CVS, Target, Kroger, and Harris Teeter, among others.
You will pay an average of $771.93 for Ezetimibe-Simvastatin without insurance, but only $37.19 with a SingleCare Ezetimibe-Simvastatin coupon.
Ezetimibe-Simvastatin copay costs may vary greatly depending on the dosage and your insurance plan. With SingleCare, Ezetimibe-Simvastatin costs $37.19, so you should ask your pharmacist to compare your SingleCare price with your insurance Ezetimibe-Simvastatin copay. A SingleCare savings card typically saves you up to 80% off on your prescription drugs.
Ezetimibe-Simvastatin is usually covered by Medicare Advantage or Medicare Part D prescription drug plans, but the brand-name version, Vytorin, is not. For patients without Medicare, bring a SingleCare Ezetimibe-Simvastatin coupon to the pharmacy when you fill your prescription. With a SingleCare discount card, the price of Ezetimibe-Simvastatin is only $37.19, which may be lower than most insurance copays.
Ezetimibe-Simvastatin is a generic prescription cholesterol-reducing drug that is a generic alternative to brand-name Vytorin. Ezetimibe-Simvastatin is supplied by a host of generic manufacturers, including Amneal, Dr. Reddy's, ANI, Glenmark, and several others. If you have a prescription for Vytorin or want more information, just search the SingleCare website or app. You will also find savings coupons for Vytorin.
Ezetimibe-Simvastatin is a combination prescription drug that reduces “bad” cholesterol (LDL cholesterol) and fats (triglycerides) in the bloodstream, both of which increase the risk of stroke and heart attack. Ezetimibe-Simvastatin is prescribed to patients diagnosed with high cholesterol or who have inherited a high cholesterol condition (Homozygous Familial Hypercholesterolemia, or HoFH).
The active ingredients in Ezetimibe-Simvastatin both reduce the liver's production of cholesterol (simvastatin) and block the body's ability to absorb dietary cholesterol through the intestines (ezetimibe).
Statins, like simvastatin, block proteins that are critical for making LDL cholesterol in the liver. Statins may help reduce cholesterol plaques that have already formed in blood vessels. Ezetimibe also blocks a protein, one that is critical to the ability of the intestines to absorb cholesterol from food.
Ezetimibe-Simvastatin is taken as a tablet once daily in the evening with or without food.
The most common physical side effect of Ezetimibe-Simvastatin is muscle pain and cramping, which can range from mild weakness or soreness to severe pain. Consult with your physician if you experience serious muscle pain. Other physical side effects include but are not limited to headache, numbness, dizziness, diarrhea, nausea, vomiting, joint pain, back pain, trouble sleeping, and cold symptoms.
The most common mental or mood changes that result from taking Ezetimibe-Simvastatin are memory loss and confusion, which can range from mild mental fuzziness to severe enough to interfere with daily tasks. Less commonly, Ezetimibe-Simvastatin can also cause depression. These side effects improve when the medication is stopped. Consult with your prescribing physician if you experience confusion and memory loss while taking Ezetimibe-Simvastatin.
The most serious but less common side effects of Ezetimibe-Simvastatin are liver damage, muscle damage, and increased blood sugar. Severe muscle damage can cause kidney problems and kidney failure. It is not uncommon for a prescribing physician to perform blood tests before and after starting Ezetimibe-Simvastatin to monitor liver, muscle, and blood sugar problems.
Allergic reactions are rare. Get emergency medical help if you notice signs of an allergic reaction such as facial swelling, hives, rash, or trouble breathing.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved