What is Fosaprepitant Dimeglumine: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Fosaprepitant Dimeglumine overview

BRAND NAMES:

  • Emend Novaplus, PremierPro Rx Emend, Emend

Generic Names:

  • Fosaprepitant Dimeglumine

Uses:

  • Prevents nausea and vomiting caused by cancer treatment (chemotherapy).

Therapeutic Classes:

  • Antiemetic

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Fosaprepitant Dimeglumine used for?

What form(s) does Fosaprepitant Dimeglumine come in

  • Injectable

What are common Fosaprepitant Dimeglumine doses?

  • Solution Reconstituted 150MG

Common Fosaprepitant Dimeglumine prescriptions

  • Fosaprepitant Dimeglumine
    150mg solution reconstituted

How to take Fosaprepitant Dimeglumine

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeA nurse or other health provider will give you this medicine. The medicine must be given slowly, so the needle will have to stay for at least 30 minutes.

  • This medicine is usually given on the first day of your cancer treatment along with other medicines. This medicine is not for long-term use, but you may need to use it again if you have more cancer treatments.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • This medicine is usually given on the first day of your cancer treatment along with other medicines. This medicine is not for long-term use, but you may need to use it again if you have more cancer treatments.

  • Injection routeA nurse or other health provider will give you this medicine. The medicine must be given slowly, so the needle will have to stay for at least 30 minutes.

What to do if you miss a dose of Fosaprepitant Dimeglumine

Fosaprepitant Dimeglumine contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to fosaprepitant or aprepitant.

Fosaprepitant Dimeglumine warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease.

  • Birth control pills may not work as well while you are receiving this medicine. Use another form of birth control (including condoms, spermicides) during treatment and for 1 month after your last dose.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Warmth or redness in your face, neck, arms, or upper chest

Fosaprepitant Dimeglumine interactions

  • Also tell your doctor if you are using any of the following:Carbamazepine, clarithromycin, dexamethasone, diltiazem, itraconazole, ketoconazole, methylprednisolone, nefazodone, nelfinavir, phenytoin, rifampin, ritonavir, troleandomycinBlood thinner (including warfarin)Sedative (including alprazolam, midazolam, triazolam)

  • Tell your doctor about all cancer medicines you take. Some cancer medicines, including ifosfamide, vinblastine, and vincristine, can interact with this medicine and cause side effects.

  • You should not receive this medicine together with pimozide.

Fosaprepitant Dimeglumine side effects

Serious Side Effects

  • Fever, chills, headache, nausea, vomiting

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Warmth or redness in your face, neck, arms, or upper chest

Less Serious Side Effects

  • Diarrhea

  • Tiredness

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.