What is Heplisav-B: Uses, Warnings & Interactions

What is Heplisav-B: Uses, Warnings & Interactions

Updated May 14, 2025 • Published Dec 30, 2020

Check our best Heplisav-B prices

Heplisav-B overview

BRAND NAMES:

Heplisav-B

Generic Names:

Heplisav-B

Uses:

Prevents hepatitis B infection.

Therapeutic Classes:

Vaccine

Forms:

Injectable

How it’s taken:

By injection

What is Heplisav-B used for?

What form(s) does Heplisav-B come in

Injectable

What are common Heplisav-B doses?

Syringe 0.5ML of 20MCG/0.5ML

Common Heplisav-B prescriptions

Heplisav-B
0.5ml of 20mcg/0.5ml syringe
Heplisav-B
0.5ml of 20mcg/0.5ml vial

How to take Heplisav-B

Missed dose: Injection routeCall your doctor or pharmacist for instructions.
Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles. It is usually given in the shoulder area.
Injection routeA nurse or other health provider will give you this medicine.
Injection routeA nurse or other health provider will give you this medicine.
Missed dose: Injection routeCall your doctor or pharmacist for instructions.
Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles. It is usually given in the shoulder area.

What to do if you miss a dose of Heplisav-B

Heplisav-B contraindications

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to hepatitis B vaccine or to yeast.

Heplisav-B warnings

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Tell your doctor if you are pregnant or breastfeeding, or if you have an active infection (including hepatitis B) or a weak immune system.

Heplisav-B interactions

Some medicines may affect how hepatitis B vaccine works. Tell your doctor if you are receiving immune globulin.

Heplisav-B side effects

Serious Side Effects

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

Pain, itching, burning, swelling, or a lump under your skin where the shot was given